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Insight into the function of Group I and Group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders

Behavioural pharmacology, 2003-07, Vol.14 (4), p.257-277

2003

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Evaluation of peripheral versus central effects of GABA(B) receptor activation using a novel, positive allosteric modulator of the GABA(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

British journal of pharmacology, 2014-11, Vol.171 (21), p.4941

2014

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Evaluation of peripheral versus central effects of GABAB receptor activation using a novel, positive allosteric modulator of the GABAB receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

British journal of pharmacology, 2014-11, Vol.171 (21), p.4941-4954

2014

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Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro

The Journal of pharmacology and experimental therapeutics, 1997-12, Vol.283 (3), p.1285

1997

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1.139 ANTI-PARKINSONIAN EFFECTS OF ADX48621 A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR (NAM), IN THE RAT HALOPERIDOL INDUCED CATALEPSY MODEL

Parkinsonism & related disorders, 2012, Vol.18, p.S45-S45

2012

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5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

The Journal of pharmacology and experimental therapeutics, 1998-08, Vol.286 (2), p.913

1998

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Stepwise control of osteogenic differentiation by 5-HT2B receptor signaling: Nitric oxide production and phospholipase A2 activation

Cellular signalling, 2006-05, Vol.18 (5), p.628-639

2006

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2.231 ADX48621, A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR ALLEVIATES L-DOPA-INDUCED CHOREA AND DYSTONIA IN THE MPTP MACAQUE MODEL OF PARKINSON'S DISEASE

Parkinsonism & related disorders, 2012, Vol.18, p.S122-S122

2012

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Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1

Neuropharmacology, 2001, Vol.40 (1), p.20-27

2001

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Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist

The Journal of pharmacology and experimental therapeutics, 2002-09, Vol.302 (3), p.940

2002

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Characterization of [3H]Quisqualate Binding to Recombinant Rat Metabotropic Glutamate 1a and 5a Receptors and to Rat and Human Brain Sections

Journal of neurochemistry, 2000-12, Vol.75 (6), p.2590-2601

2000

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NADPH Oxidase and Extracellular Regulated Kinases 1/2 Are Targets of Prion Protein Signaling in Neuronal and Nonneuronal Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (23), p.13326-13331

2003

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Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors

Brain research, 2000-06, Vol.867 (1), p.165-172

2000

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Positive Allosteric Modulators of Metabotropic Glutamate 1 Receptor: Characterization, Mechanism of Action, and Binding Site

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (23), p.13402-13407

2001

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Stepwise control of osteogenic differentiation by 5-HT(2B) receptor signaling: nitric oxide production and phospholipase A2 activation

Cellular signalling, 2006-05, Vol.18 (5), p.628-639

2006

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Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor

The Journal of biological chemistry, 2003-03, Vol.278 (10), p.8340-8347

2003

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Evaluation of peripheral versus central effects of GABA B receptor activation using a novel, positive allosteric modulator of the GABA B receptor ADX 71943, a pharmacological tool compound with a fully peripheral activity profile

British journal of pharmacology, 2014-11, Vol.171 (21), p.4941-4954

2014

Volltextzugriff (PDF)

Evaluation of peripheral versus central effects of GABA sub(B) receptor activation using a novel, positive allosteric modulator of the GABA sub(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

British journal of pharmacology, 2014-11, Vol.171 (21), p.4941-4954

2014

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Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity

The Journal of neuroscience, 2002-08, Vol.22 (15), p.6713-6723

2002

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Pharmacological characterization of metabotropic glutamate receptors linked to the inhibition of adenylate cyclase activity in rat striatal slices

Neuropharmacology, 1997-07, Vol.36 (7), p.933-940

1997

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Developmental Changes in NMDA Receptor Glycine Affinity and Ifenprodil Sensitivity Reveal Three Distinct Populations of NMDA Receptors in Individual Rat Cortical Neurons

The Journal of neuroscience, 1998-03, Vol.18 (6), p.1935-1943

1998

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In Vitro Binding Properties in Rat Brain of [3H]Ro 25‐6981, a Potent and Selective Antagonist of NMDA Receptors Containing NR2B Subunits

Journal of neurochemistry, 1998-05, Vol.70 (5), p.2147-2155

1998

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One-step purification of the serotonin transporter located at the human platelet plasma membrane

The Journal of biological chemistry, 1992-06, Vol.267 (16), p.11344-11351

1992

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The 5-HT2B Receptor Controls the Overall 5-HT Transport System in the 1C11 Serotonergic Cell Line

Annals of the New York Academy of Sciences, 1998-12, Vol.861 (1), p.247-247

1998

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Increase of human platelet serotonin uptake by atypical histamine receptors

American journal of physiology. Regulatory, integrative and comparative physiology, 1994-02, Vol.266 (2), p.526-R536

1994

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Insight into the function of Group I and Group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders

Evaluation of peripheral versus central effects of GABA(B) receptor activation using a novel, positive allosteric modulator of the GABA(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

Evaluation of peripheral versus central effects of GABAB receptor activation using a novel, positive allosteric modulator of the GABAB receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro

1.139 ANTI-PARKINSONIAN EFFECTS OF ADX48621 A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR (NAM), IN THE RAT HALOPERIDOL INDUCED CATALEPSY MODEL

5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential

Stepwise control of osteogenic differentiation by 5-HT2B receptor signaling: Nitric oxide production and phospholipase A2 activation

2.231 ADX48621, A MGLUR5 NEGATIVE ALLOSTERIC MODULATOR ALLEVIATES L-DOPA-INDUCED CHOREA AND DYSTONIA IN THE MPTP MACAQUE MODEL OF PARKINSON'S DISEASE

Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1

Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist

Characterization of [3H]Quisqualate Binding to Recombinant Rat Metabotropic Glutamate 1a and 5a Receptors and to Rat and Human Brain Sections

NADPH Oxidase and Extracellular Regulated Kinases 1/2 Are Targets of Prion Protein Signaling in Neuronal and Nonneuronal Cells

Reducing conditions differentially affect the functional and structural properties of group-I and -II metabotropic glutamate receptors

Positive Allosteric Modulators of Metabotropic Glutamate 1 Receptor: Characterization, Mechanism of Action, and Binding Site

Stepwise control of osteogenic differentiation by 5-HT(2B) receptor signaling: nitric oxide production and phospholipase A2 activation

Mutational Analysis and Molecular Modeling of the Allosteric Binding Site of a Novel, Selective, Noncompetitive Antagonist of the Metabotropic Glutamate 1 Receptor

Evaluation of peripheral versus central effects of GABA B receptor activation using a novel, positive allosteric modulator of the GABA B receptor ADX 71943, a pharmacological tool compound with a fully peripheral activity profile

Evaluation of peripheral versus central effects of GABA sub(B) receptor activation using a novel, positive allosteric modulator of the GABA sub(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile

Severe Impairment of NMDA Receptor Function in Mice Carrying Targeted Point Mutations in the Glycine Binding Site Results in Drug-Resistant Nonhabituating Hyperactivity

Pharmacological characterization of metabotropic glutamate receptors linked to the inhibition of adenylate cyclase activity in rat striatal slices

Developmental Changes in NMDA Receptor Glycine Affinity and Ifenprodil Sensitivity Reveal Three Distinct Populations of NMDA Receptors in Individual Rat Cortical Neurons

In Vitro Binding Properties in Rat Brain of [3H]Ro 25‐6981, a Potent and Selective Antagonist of NMDA Receptors Containing NR2B Subunits

One-step purification of the serotonin transporter located at the human platelet plasma membrane

The 5-HT2B Receptor Controls the Overall 5-HT Transport System in the 1C11 Serotonergic Cell Line

Increase of human platelet serotonin uptake by atypical histamine receptors

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