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Mechanisms linking circadian clocks, sleep, and neurodegeneration

Science (American Association for the Advancement of Science), 2016-11, Vol.354 (6315), p.1004-1008

2016

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Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

Nature neuroscience, 2015-06, Vol.18 (6), p.800-806

2015

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Association between circadian rhythms and neurodegenerative diseases

Lancet neurology, 2019-03, Vol.18 (3), p.307-318

2019

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The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration

Neurobiology of disease, 2020-06, Vol.139, p.104832-104832, Article 104832

2020

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Editorial overview: Introduction to neurobiology of disease

Current opinion in neurobiology, 2024-06, Vol.86, p.102875-102875, Article 102875

2024

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Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease

Experimental & molecular medicine, 2015-03, Vol.47 (3), p.e148-e148

2015

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Circadian clock disruption in neurodegenerative diseases: cause and effect?

Frontiers in pharmacology, 2015-02, Vol.6, p.29-29

Musiek, Erik S

2015

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Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer Disease

JAMA neurology, 2018-05, Vol.75 (5), p.582

2018

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Lecanamab Ushers in a New Era of Anti‐Amyloid Therapy for Alzheimer's Disease

Annals of neurology, 2023-05, Vol.93 (5), p.877-880

2023

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Aducanumab for Alzheimer disease: the amyloid hypothesis moves from bench to bedside

The Journal of clinical investigation, 2021-10, Vol.131 (20), p.1-4

2021

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Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease

Aging cell, 2020-02, Vol.19 (2), p.e13078-n/a

2020

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Possible Consequences of the Approval of a Disease-Modifying Therapy for Alzheimer Disease

JAMA neurology, 2021-02, Vol.78 (2), p.141

2021

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Regulation of amyloid-β dynamics and pathology by the circadian clock

The Journal of experimental medicine, 2018-04, Vol.215 (4), p.1059-1068

2018

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Time-restricted feeding and Alzheimer’s disease: you are when you eat

Trends in molecular medicine, 2023-12, Vol.29 (12), p.974-975

2023

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Dural lymphatics regulate clearance of extracellular tau from the CNS

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.11-11, Article 11

2019

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Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden

Scientific reports, 2022-02, Vol.12 (1), p.1796-1796, Article 1796

2022

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Chi3l1 /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

Science translational medicine, 2020-12, Vol.12 (574)

2020

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Aducanumab and the “post-amyloid” era of Alzheimer research?

Neuron (Cambridge, Mass.), 2021-10, Vol.109 (19), p.3045-3047

2021

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Circadian regulation of astrocyte function: implications for Alzheimer’s disease

Cellular and molecular life sciences : CMLS, 2020-03, Vol.77 (6), p.1049-1058

2020

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Targeting Sleep and Circadian Function in the Prevention of Alzheimer Disease

JAMA neurology, 2022-09, Vol.79 (9), p.835

2022

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Alzheimer's Disease and Sleep-Wake Disturbances: Amyloid, Astrocytes, and Animal Models

The Journal of neuroscience, 2018-03, Vol.38 (12), p.2901-2910

2018

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Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (20), p.e2220551120-e2220551120

2023

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Circadian clock protein Rev-erbα regulates neuroinflammation

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (11), p.5102-5107

2019

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Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Science translational medicine, 2016-02, Vol.8 (324), p.324ra16

2016

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Evaluating Circadian Dysfunction in Mouse Models of Alzheimer's Disease: Where Do We Stand?

Frontiers in neuroscience, 2020-07, Vol.14, p.703-703

2020

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Mechanisms linking circadian clocks, sleep, and neurodegeneration

Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

Association between circadian rhythms and neurodegenerative diseases

The wrinkling of time: Aging, inflammation, oxidative stress, and the circadian clock in neurodegeneration

Editorial overview: Introduction to neurobiology of disease

Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease

Circadian clock disruption in neurodegenerative diseases: cause and effect?

Circadian Rest-Activity Pattern Changes in Aging and Preclinical Alzheimer Disease

Lecanamab Ushers in a New Era of Anti‐Amyloid Therapy for Alzheimer's Disease

Aducanumab for Alzheimer disease: the amyloid hypothesis moves from bench to bedside

Inhibition of REV‐ERBs stimulates microglial amyloid‐beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer’s disease

Possible Consequences of the Approval of a Disease-Modifying Therapy for Alzheimer Disease

Regulation of amyloid-β dynamics and pathology by the circadian clock

Time-restricted feeding and Alzheimer’s disease: you are when you eat

Dural lymphatics regulate clearance of extracellular tau from the CNS

Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden

Chi3l1 /YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis

Aducanumab and the “post-amyloid” era of Alzheimer research?

Circadian regulation of astrocyte function: implications for Alzheimer’s disease

Targeting Sleep and Circadian Function in the Prevention of Alzheimer Disease

Alzheimer's Disease and Sleep-Wake Disturbances: Amyloid, Astrocytes, and Animal Models

Circadian clock protein BMAL1 broadly influences autophagy and endolysosomal function in astrocytes

Circadian clock protein Rev-erbα regulates neuroinflammation

Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Evaluating Circadian Dysfunction in Mouse Models of Alzheimer's Disease: Where Do We Stand?

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