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Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2018-04, Vol.150, p.506-524

2018

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Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2016-10, Vol.59 (19), p.8967-9004

2016

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Discovery of in Vivo Chemical Probes for Treating Alzheimer’s Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors

ACS chemical neuroscience, 2019-03, Vol.10 (3), p.1765-1782

2019

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Impact of Scaffold Exploration on Novel Dual-Acting Histone Deacetylases and Phosphodiesterase 5 Inhibitors for the Treatment of Alzheimer’s Disease

ACS chemical neuroscience, 2017-03, Vol.8 (3), p.638-661

2017

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Synthesis of novel benzoxaborole-containing phenylalanine analogues

Tetrahedron letters, 2011-09, Vol.52 (38), p.4924-4926

2011

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Resin-based iron-manganese binary oxide for phosphate selective removal

Environmental science and pollution research international, 2023, Vol.30 (2), p.4642-4652

2023

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Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma

Journal of medicinal chemistry, 2021-03, Vol.64 (6), p.3392-3426

2021

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Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6518-6545

2018

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Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (1), p.6-10

2018

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Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Journal of medicinal chemistry, 2024-04, Vol.67 (7), p.5758-5782

2024

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Detailed Exploration around 4‑Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6546-6573

2018

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Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides

Bioorganic & medicinal chemistry letters, 2021-07, Vol.43, p.128089-128089, Article 128089

2021

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Multitarget Approach for the Treatment of Alzheimer’s Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles

ACS chemical neuroscience, 2019-09, Vol.10 (9), p.4076-4101

2019

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Visible-light-induced peroxymonosulfate activation over ZnFe2O4 fine nanoparticles for ofloxacin degradation

Elementa (Washington, D.C.), 2021-06, Vol.9 (1)

2021

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Photodecarboxylation of benzoyl-substituted biphenylacetic acids and photo-retro-Aldol reaction of related compounds in aqueous solution. Acid and base catalysis of reaction

Journal of photochemistry and photobiology. A, Chemistry., 2009-04, Vol.204 (1), p.52-62

2009

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Novel synthesis of isoxazoline indolizine amides for potential application to tropical diseases

Tetrahedron letters, 2014-03, Vol.55 (11), p.1936-1938

2014

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Design, Synthesis, and Biological Evaluation of Novel Matrix Metalloproteinase Inhibitors As Potent Antihemorrhagic Agents: From Hit Identification to an Optimized Lead

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2465-2488

2015

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Intramolecular charge transfer in photoexcited hydroxyterphenyls: Evidence for formation of terphenyl quinone methides in aqueous solution

Journal of photochemistry and photobiology. A, Chemistry., 2008-07, Vol.198 (1), p.26-33

2008

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Synthesis and antibacterial evaluation of a novel tricyclic oxaborole-fused fluoroquinolone

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.963-966

2013

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Using Vaccinia Virus as a Model System to Understand Microtubule-Based Transport

Xu, Amadeus Musheng

2022

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Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

ACS medicinal chemistry letters, 2018-05, Vol.9 (5), p.428-433

2018

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Photogeneration and Chemistry of Biphenyl Quinone Methides from Hydroxybiphenyl Methanols

Photochemistry and photobiology, 2006-01, Vol.82 (1), p.50-56

2006

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Photohydration and Photosolvolysis of Biphenyl Alkenes and Alcohols via Biphenyl Quinone Methide-type Intermediates and Diarylmethyl Carbocations

Journal of the American Chemical Society, 2003-10, Vol.125 (42), p.12961-12970

2003

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Excited state intramolecular redox reaction of 2-(hydroxymethyl)anthraquinone in aqueous solution

Chemical communications (Cambridge, England), 2002-01 (2), p.136-137

2002

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Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer’s Disease

Discovery of in Vivo Chemical Probes for Treating Alzheimer’s Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors

Impact of Scaffold Exploration on Novel Dual-Acting Histone Deacetylases and Phosphodiesterase 5 Inhibitors for the Treatment of Alzheimer’s Disease

Synthesis of novel benzoxaborole-containing phenylalanine analogues

Resin-based iron-manganese binary oxide for phosphate selective removal

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with In Vivo Efficacy in Multiple Myeloma

Discovery of Reversible DNA Methyltransferase and Lysine Methyltransferase G9a Inhibitors with Antitumoral in Vivo Efficacy

Identification of a 4-fluorobenzyl l-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases

Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis

Detailed Exploration around 4‑Aminoquinolines Chemical Space to Navigate the Lysine Methyltransferase G9a and DNA Methyltransferase Biological Spaces

Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides

Multitarget Approach for the Treatment of Alzheimer’s Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles

Visible-light-induced peroxymonosulfate activation over ZnFe2O4 fine nanoparticles for ofloxacin degradation

Photodecarboxylation of benzoyl-substituted biphenylacetic acids and photo-retro-Aldol reaction of related compounds in aqueous solution. Acid and base catalysis of reaction

Novel synthesis of isoxazoline indolizine amides for potential application to tropical diseases

Design, Synthesis, and Biological Evaluation of Novel Matrix Metalloproteinase Inhibitors As Potent Antihemorrhagic Agents: From Hit Identification to an Optimized Lead

Intramolecular charge transfer in photoexcited hydroxyterphenyls: Evidence for formation of terphenyl quinone methides in aqueous solution

Synthesis and antibacterial evaluation of a novel tricyclic oxaborole-fused fluoroquinolone

Using Vaccinia Virus as a Model System to Understand Microtubule-Based Transport

Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

Photogeneration and Chemistry of Biphenyl Quinone Methides from Hydroxybiphenyl Methanols

Photohydration and Photosolvolysis of Biphenyl Alkenes and Alcohols via Biphenyl Quinone Methide-type Intermediates and Diarylmethyl Carbocations

Excited state intramolecular redox reaction of 2-(hydroxymethyl)anthraquinone in aqueous solution

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