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The role of inflammasomes in kidney disease

Nature reviews. Nephrology, 2019-08, Vol.15 (8), p.501-520

2019

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Gasdermins and pyroptosis in the kidney

Nature reviews. Nephrology, 2023-05, Vol.19 (5), p.337-350

2023

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Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

Journal of the American Society of Nephrology, 2018-04, Vol.29 (4), p.1165-1181

2018

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Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

Science (American Association for the Advancement of Science), 2010-10, Vol.330 (6002), p.362-366

2010

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The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

Journal of the American Society of Nephrology, 2010-10, Vol.21 (10), p.1732-1744

2010

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

Nature, 2008-03, Vol.452 (7183), p.103-107

2008

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Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

Nature medicine, 2012-04, Vol.18 (4), p.600-604

2012

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Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

Cell reports (Cambridge), 2018-11, Vol.25 (6), p.1525-1536.e7

2018

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The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

Cell reports (Cambridge), 2017-12, Vol.21 (13), p.3653-3661

2017

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Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk

Cell reports (Cambridge), 2020-10, Vol.33 (1), p.108233-108233, Article 108233

2020

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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

Blood, 2011-06, Vol.117 (24), p.6459-6468

2011

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Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

Journal of Virology, 2013-04, Vol.87 (7), p.3655-3667

2013

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NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways

Archives of biochemistry and biophysics, 2019-07, Vol.670, p.4-14

2019

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The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain

Molecular pharmacology, 2019-08, Vol.96 (2), p.259-271

2019

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AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis

The Journal of immunology (1950), 2021-12, Vol.207 (11), p.2799-2812

2021

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Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: toward a new therapy for BK virus infection

Transplantation, 2010-12, Vol.90 (12), p.1450

2010

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Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

Gastroenterology (New York, N.Y. 1943), 2010-08, Vol.139 (2), p.542-552.e3

2010

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Inflammasomes in the CNS

Nature reviews. Neuroscience, 2014-02, Vol.15 (2), p.84-97

2014

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Biochemical and structural aspects of the ATP‐binding domain in inflammasome‐forming human NLRP proteins

IUBMB life, 2013-10, Vol.65 (10), p.851-862

2013

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Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry

Kidney & blood pressure research, 2020-03, Vol.45 (2), p.233-248

2020

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Nucleotide-Binding Oligomerization Domain-Like Receptors and Inflammasomes in the Pathogenesis of Non-Microbial Inflammation and Diseases

Journal of innate immunity, 2012-01, Vol.4 (1), p.16-30

2012

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The Inflammasomes in Kidney Disease

Journal of the American Society of Nephrology, 2011-06, Vol.22 (6), p.1007-1018

2011

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Serum Protein Signatures Using Aptamer-Based Proteomics for Minimal Change Disease and Membranous Nephropathy

Kidney international reports, 2022-07, Vol.7 (7), p.1539-1556

2022

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A survey of patient perspectives on the research use of health information and biospecimens

BMC medical ethics, 2016-08, Vol.17 (1), p.48-48, Article 48

2016

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The role of inflammasomes in kidney disease

Gasdermins and pyroptosis in the kidney

Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome

The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition

Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9–dependent innate immune responses in the liver

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways

The Pore-Lipid Interface: Role of Amino-Acid Determinants of Lipophilic Access by Ivabradine to the hERG1 Pore Domain

AIM2 Suppresses Inflammation and Epithelial Cell Proliferation during Glomerulonephritis

Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: toward a new therapy for BK virus infection

Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

Inflammasomes in the CNS

Biochemical and structural aspects of the ATP‐binding domain in inflammasome‐forming human NLRP proteins

Detecting Proteomic Indicators to Distinguish Diabetic Nephropathy from Hypertensive Nephrosclerosis by Integrating Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging with High-Mass Accuracy Mass Spectrometry

The anti-sigma factor MucA of Pseudomonas aeruginosa: Dramatic differences of a mucA22 vs. a ΔmucA mutant in anaerobic acidified nitrite sensitivity of planktonic and biofilm bacteria in vitro and during chronic murine lung infection

Nucleotide-Binding Oligomerization Domain-Like Receptors and Inflammasomes in the Pathogenesis of Non-Microbial Inflammation and Diseases

The Inflammasomes in Kidney Disease

Serum Protein Signatures Using Aptamer-Based Proteomics for Minimal Change Disease and Membranous Nephropathy

A survey of patient perspectives on the research use of health information and biospecimens

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