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Discovery and Structure–Activity Relationships of Pyrrolone Antimalarials

Journal of medicinal chemistry, 2013-04, Vol.56 (7), p.2975-2990

2013

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Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

Journal of antimicrobial chemotherapy, 2007-06, Vol.59 (6), p.1194-1196

2007

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Antimycobacterial activities of novel fluoroquinolones

Biomedicine & pharmacotherapy, 2009-01, Vol.63 (1), p.27-35

2009

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Synthesis, Antiviral and Cytotoxic Activity of 6-Bromo-2,3-disubstituted-4(3H)-quinazolinones

Biological and Pharmaceutical Bulletin, 2003, Vol.26(9), pp.1278-1282

2003

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Synthesis, antimycobacterial activities and phototoxic evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic acid derivatives

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2008-09, Vol.4 (5), p.482-491

2008

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Discovery and optimisation studies of antimalarial phenotypic hits

European journal of medicinal chemistry, 2015-10, Vol.103, p.530-538

2015

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Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.409-423

2022

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Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids

European journal of medicinal chemistry, 2009, Vol.44 (1), p.345-358

2009

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Antimycobacterial Activities of Novel 1-(Cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic Acid

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.6232-6239

2007

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Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno-[3,2-c]pyridin-3-yl derivatives

European journal of medicinal chemistry, 2010, Vol.45 (1), p.120-123

2010

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Novel ofloxacin derivatives: Synthesis, antimycobacterial and toxicological evaluation

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1229-1236

2008

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Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

ACS infectious diseases, 2017-01, Vol.3 (1), p.18-33

2017

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Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2- a]quinoline-6-carboxylic acid

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (6), p.3408-3418

2008

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Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents

ChemMedChem, 2013-09, Vol.8 (9), p.1537-1544

2013

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Antitubercular activities of novel benzothiazolo naphthyridone carboxylic acid derivatives endowed with high activity toward multi-drug resistant tuberculosis

Biomedicine & pharmacotherapy, 2009-01, Vol.63 (1), p.11-18

2009

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Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl‑l‑cysteine Synthetase (CoaB) Activity

ACS infectious diseases, 2021-06, Vol.7 (6), p.1666-1679

2021

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Synthesis and antimycobacterial evaluation of newer 1-cyclopropyl-1,4-dihydro-6-fluoro-7-(substituted secondary amino)-8-methoxy-5-(sub)-4-oxoquinoline-3-carboxylic acids

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (5), p.2558-2569

2008

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Antimycobacterial and phototoxic evaluation of novel 6-fluoro/nitro-4-oxo-7-(sub)-4H-[1,3]thiazeto [3,2-a]quinoline-3-carboxylic acid

International journal of antimicrobial agents, 2008-04, Vol.31 (4), p.337-344

2008

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Aromatic amino analogues of artemisinin: synthesis and in vivo antimalarial activity

Medicinal chemistry research, 2010-07, Vol.19 (6), p.524-532

2010

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Discovery of novel antitubercular 2,10-dihydro-4a H-chromeno[3,2- c]pyridin-3-yl derivatives

European journal of medicinal chemistry, 2010, Vol.45 (1), p.120-123

2010

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Synthesis and in-vitro Antimycobacterial Evaluation of 1-(Cyclopropyl/2,4-difluorophenyl/tert-butyl)-1,4-dihydro- 8-methyl-6-nitro-4-oxo-7-(substituted secondary amino)quinoline-3-carboxylic acids

Archiv der Pharmazie (Weinheim), 2009-02, Vol.342 (2), p.100-112

2009

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Synthesis, anti-HIV and antitubercular activities of nelfinavir diester derivatives

Biomedicine & pharmacotherapy, 2008-01, Vol.62 (1), p.1-5

2008

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Synthesis, anti-HIV and antitubercular activities of nelfinavir diester derivatives : Human and animal retrovirruses

Biomedicine & pharmacotherapy, 2008, Vol.62 (1), p.1-5

2008

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Discovery and Structure–Activity Relationships of Pyrrolone Antimalarials

Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth

Antimycobacterial activities of novel fluoroquinolones

Synthesis, Antiviral and Cytotoxic Activity of 6-Bromo-2,3-disubstituted-4(3H)-quinazolinones

Synthesis, antimycobacterial activities and phototoxic evaluation of 5H-thiazolo[3,2-a]quinoline-4-carboxylic acid derivatives

Discovery and optimisation studies of antimalarial phenotypic hits

Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target

Synthesis and antimycobacterial activities of novel 6-nitroquinolone-3-carboxylic acids

Antimycobacterial Activities of Novel 1-(Cyclopropyl/tert-butyl/4-fluorophenyl)-1,4-dihydro- 6-nitro-4-oxo-7-(substituted secondary amino)-1,8-naphthyridine-3-carboxylic Acid

Discovery of novel antitubercular 2,10-dihydro-4aH-chromeno-[3,2-c]pyridin-3-yl derivatives

Novel ofloxacin derivatives: Synthesis, antimycobacterial and toxicological evaluation

Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis

Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2- a]quinoline-6-carboxylic acid

Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents

2‑Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

Antitubercular activities of novel benzothiazolo naphthyridone carboxylic acid derivatives endowed with high activity toward multi-drug resistant tuberculosis

Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl‑l‑cysteine Synthetase (CoaB) Activity

Synthesis and antimycobacterial evaluation of newer 1-cyclopropyl-1,4-dihydro-6-fluoro-7-(substituted secondary amino)-8-methoxy-5-(sub)-4-oxoquinoline-3-carboxylic acids

Antimycobacterial and phototoxic evaluation of novel 6-fluoro/nitro-4-oxo-7-(sub)-4H-[1,3]thiazeto [3,2-a]quinoline-3-carboxylic acid

Aromatic amino analogues of artemisinin: synthesis and in vivo antimalarial activity

Discovery of novel antitubercular 2,10-dihydro-4a H-chromeno[3,2- c]pyridin-3-yl derivatives

Synthesis and in-vitro Antimycobacterial Evaluation of 1-(Cyclopropyl/2,4-difluorophenyl/tert-butyl)-1,4-dihydro- 8-methyl-6-nitro-4-oxo-7-(substituted secondary amino)quinoline-3-carboxylic acids

Synthesis, anti-HIV and antitubercular activities of nelfinavir diester derivatives

Synthesis, anti-HIV and antitubercular activities of nelfinavir diester derivatives : Human and animal retrovirruses

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