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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

PloS one, 2018-05, Vol.13 (5), p.e0196791-e0196791

2018

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Targeting protein-protein interactions: Lessons from p53/MDM2

Biopolymers, 2007, Vol.88 (5), p.657-686

2007

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Purification of N-acetylgalactosamine-modified-oligonucleotides using orthogonal anion-exchange and mixed-mode chromatography approaches

Journal of Chromatography A, 2022-01, Vol.1661, p.462679, Article 462679

2022

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Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2299-2314

2015

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Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2299-2314

2015

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Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1

Journal of medicinal chemistry, 2016-03, Vol.59 (6), p.2704-2717

2016

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Purification of guanine-quadruplex using monolithic stationary phase under ion-exchange conditions

Journal of Chromatography A, 2020-12, Vol.1634, p.461633, Article 461633

2020

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antiangiogenic neurokinin-B/thromboxane A2 regulatory axis

The Journal of cell biology, 2006-09, Vol.174 (7), p.1047-1058

2006

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Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx‑V Peptide 5‑Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9500-9512

2018

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Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

Journal of medicinal chemistry, 2015-09, Vol.58 (17), p.6784-6802

2015

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PADLOC: A Powerful Tool to Assign Disulfide Bond Connectivities in Peptides and Proteins by NMR Spectroscopy

Analytical chemistry (Washington), 2012-01, Vol.84 (1), p.262-266

2012

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Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (21), p.4866-4871

2015

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Application of Microwave Irradiation to the Synthesis of 14-Helical β-Peptides

Organic letters, 2005-04, Vol.7 (8), p.1517-1520

2005

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Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease

Nucleic acid therapeutics, 2021-10, Vol.31 (5), p.324

2021

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Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx‑1 Peptide–Antibody Conjugates

ACS chemical biology, 2017-09, Vol.12 (9), p.2427-2435

2017

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Discovery of Tarantula Venom-Derived Na V 1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Journal of medicinal chemistry, 2018-11, Vol.61 (21), p.9500-9512

2018

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Liver-specific mitochondrial amidoxime-reducing component 1 (Mtarc1) knockdown protects the liver from diet-induced MASH in multiple mouse models

Hepatology communications, 2024-05, Vol.8 (5)

2024

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Exploration of Backbone Space in Foldamers Containing α- and β-Amino Acid Residues: Developing Protease-Resistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL

Chembiochem : a European journal of chemical biology, 2007-05, Vol.8 (8), p.903-916

2007

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Parallel synthesis of peptide libraries using microwave irradiation

Nature protocols, 2007-03, Vol.2 (3), p.624-631

2007

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Efficient Synthesis of a β-Peptide Combinatorial Library with Microwave Irradiation

Journal of the American Chemical Society, 2005-09, Vol.127 (38), p.13271-13280

2005

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Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates

ACS chemical biology, 2017-09, Vol.12 (9), p.2427-2435

2017

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Asymmetric Synthesis of a New Helix-Forming β-Amino Acid: trans-4-Aminopiperidine-3-carboxylic Acid

European journal of organic chemistry, 2003-02, Vol.2003 (4), p.721-726

2003

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Solid-phase peptide synthesis using microwave irradiation

Methods in molecular biology (Clifton, N.J.), 2011, Vol.716, p.73

2011

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Discovery of Tarantula Venom-Derived NaV 1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Journal of medicinal chemistry, 2018-10, Vol.61 (21)

2018

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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V

Targeting protein-protein interactions: Lessons from p53/MDM2

Purification of N-acetylgalactosamine-modified-oligonucleotides using orthogonal anion-exchange and mixed-mode chromatography approaches

Engineering Potent and Selective Analogues of GpTx-1, a Tarantula Venom Peptide Antagonist of the NaV1.7 Sodium Channel

Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel

Single Residue Substitutions That Confer Voltage-Gated Sodium Ion Channel Subtype Selectivity in the NaV1.7 Inhibitory Peptide GpTx‑1

Purification of guanine-quadruplex using monolithic stationary phase under ion-exchange conditions

antiangiogenic neurokinin-B/thromboxane A2 regulatory axis

Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx‑V Peptide 5‑Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3

PADLOC: A Powerful Tool to Assign Disulfide Bond Connectivities in Peptides and Proteins by NMR Spectroscopy

Sustained inhibition of the NaV1.7 sodium channel by engineered dimers of the domain II binding peptide GpTx-1

Application of Microwave Irradiation to the Synthesis of 14-Helical β-Peptides

Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease

Engineering Antibody Reactivity for Efficient Derivatization to Generate NaV1.7 Inhibitory GpTx‑1 Peptide–Antibody Conjugates

Discovery of Tarantula Venom-Derived Na V 1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

Liver-specific mitochondrial amidoxime-reducing component 1 (Mtarc1) knockdown protects the liver from diet-induced MASH in multiple mouse models

Exploration of Backbone Space in Foldamers Containing α- and β-Amino Acid Residues: Developing Protease-Resistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL

Parallel synthesis of peptide libraries using microwave irradiation

Engineering Na V 1.7 Inhibitory JzTx-V Peptides with a Potency and Basicity Profile Suitable for Antibody Conjugation To Enhance Pharmacokinetics

Efficient Synthesis of a β-Peptide Combinatorial Library with Microwave Irradiation

Engineering Antibody Reactivity for Efficient Derivatization to Generate Na V 1.7 Inhibitory GpTx-1 Peptide-Antibody Conjugates

Asymmetric Synthesis of a New Helix-Forming β-Amino Acid: trans-4-Aminopiperidine-3-carboxylic Acid

Solid-phase peptide synthesis using microwave irradiation

Discovery of Tarantula Venom-Derived NaV 1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced Pruritis

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