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Biochemistry of nicotine metabolism and its relevance to lung cancer

The Journal of biological chemistry, 2021-01, Vol.296, p.100722, Article 100722

Murphy, Sharon E.

2021

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Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6

Chemical research in toxicology, 2017-01, Vol.30 (1), p.410-419

Murphy, Sharon E

2017

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Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival

PloS one, 2008-02, Vol.3 (2), p.e1651

2008

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Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

PloS one, 2019-06, Vol.14 (6), p.e0218386-e0218386

2019

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Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study

PloS one, 2017-05, Vol.12 (5), p.e0178435

2017

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CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

Carcinogenesis (New York), 2017-04, Vol.38 (4), p.411-418

2017

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Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein

PloS one, 2019-01, Vol.14 (1), p.e0210104

2019

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Predicting nicotine metabolism across ancestries using genotypes

BMC genomics, 2022-09, Vol.23 (1), p.663-663, Article 663

2022

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Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

PloS one, 2019-04, Vol.14 (4), p.e0215853-e0215853

2019

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Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home

PloS one, 2015-03, Vol.10 (3), p.e0120023

2015

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Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study

International journal of cancer, 2016-05, Vol.138 (9), p.2161-2171

2016

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Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.2990-2995

2009

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Assessing tobacco smoke exposure in pregnancy from self-report, urinary cotinine and NNAL: a validation study using the New Hampshire Birth Cohort Study

BMJ open, 2022-02, Vol.12 (2), p.e054535-e054535

2022

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The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European–Americans

Pharmacogenetics and genomics, 2011-07, Vol.21 (7), p.403-416

2011

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Cytochrome P450 Enzymes as Catalysts of Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Tobacco Specific Carcinogen

Chemical research in toxicology, 2005-02, Vol.18 (2), p.95-110

2005

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Nicotine Metabolism in Three Ethnic/Racial Groups with Different Risks of Lung Cancer

Cancer epidemiology, biomarkers & prevention, 2008-12, Vol.17 (12), p.3526-3535

2008

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Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype

The Journal of pharmacology and experimental therapeutics, 2010-01, Vol.332 (1), p.202

2010

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CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changes

PloS one, 2013-11, Vol.8 (11), p.e79700-e79700

2013

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Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations

Clinical epigenetics, 2018-08, Vol.10 (1), p.110-110, Article 110

2018

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CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

The Journal of pharmacology and experimental therapeutics, 2007-11, Vol.323 (2), p.570

2007

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Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

JNCI : Journal of the National Cancer Institute, 2019-08, Vol.111 (8), p.811-819

2019

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Similar Exposure to a Tobacco-Specific Carcinogen in Smokeless Tobacco Users and Cigarette Smokers

Cancer epidemiology, biomarkers & prevention, 2007-08, Vol.16 (8), p.1567-1572

2007

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Similar Uptake of Lung Carcinogens by Smokers of Regular, Light, and Ultralight Cigarettes

Cancer epidemiology, biomarkers & prevention, 2005-03, Vol.14 (3), p.693-698

2005

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Relationships between Cigarette Consumption and Biomarkers of Tobacco Toxin Exposure

Cancer epidemiology, biomarkers & prevention, 2005-12, Vol.14 (12), p.2963-2968

2005

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Evaluation of Toxicant and Carcinogen Metabolites in the Urine of E-Cigarette Users Versus Cigarette Smokers

Nicotine & tobacco research, 2015-06, Vol.17 (6), p.704-709

2015

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Biochemistry of nicotine metabolism and its relevance to lung cancer

Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6

Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage

Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein

Predicting nicotine metabolism across ancestries using genotypes

Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation

Elevated levels of mercapturic acids of acrolein and crotonaldehyde in the urine of Chinese women in Singapore who regularly cook at home

Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study

Urinary Levels of Tobacco-Specific Nitrosamine Metabolites in Relation to Lung Cancer Development in Two Prospective Cohorts of Cigarette Smokers

Assessing tobacco smoke exposure in pregnancy from self-report, urinary cotinine and NNAL: a validation study using the New Hampshire Birth Cohort Study

The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European–Americans

Cytochrome P450 Enzymes as Catalysts of Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Tobacco Specific Carcinogen

Nicotine Metabolism in Three Ethnic/Racial Groups with Different Risks of Lung Cancer

Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype

CYP2B6 non-coding variation associated with smoking cessation is also associated with differences in allelic expression, splicing, and nicotine metabolism independent of common amino-acid changes

Association of internal smoking dose with blood DNA methylation in three racial/ethnic populations

CYP2A13: variable expression and role in human lung microsomal metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Racial/Ethnic Differences in Lung Cancer Incidence in the Multiethnic Cohort Study: An Update

Similar Exposure to a Tobacco-Specific Carcinogen in Smokeless Tobacco Users and Cigarette Smokers

Similar Uptake of Lung Carcinogens by Smokers of Regular, Light, and Ultralight Cigarettes

Relationships between Cigarette Consumption and Biomarkers of Tobacco Toxin Exposure

Evaluation of Toxicant and Carcinogen Metabolites in the Urine of E-Cigarette Users Versus Cigarette Smokers

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