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Reducing target binding affinity improves the therapeutic index of anti-MET antibody-drug conjugate in tumor bearing animals

PloS one, 2024-04, Vol.19 (4), p.e0293703-e0293703

2024

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Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Blood, 2009-05, Vol.113 (21), p.5277-5286

2009

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Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

Gut, 2014-12, Vol.63 (12), p.1951-1959

2014

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High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

The Journal of nutritional biochemistry, 2012-12, Vol.23 (12), p.1600-1608

2012

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Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry

Blood, 2007-08, Vol.110 (3), p.1048-1054

2007

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Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Haematologica (Roma), 2014-09, Vol.99 (9), p.1516-1524

2014

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Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency

British journal of haematology, 2009-03, Vol.144 (5), p.789-793

2009

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An apolipoprotein A-I mimetic dose-dependently increases the formation of preβ1 HDL in human plasma

Journal of lipid research, 2008-03, Vol.49 (3), p.581-587

2008

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Lessons learned from the COVID-19 pandemic and its impact on bioanalysis and drug development

Bioanalysis, 2021-08, Vol.13 (15), p.1205-1211

2021

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Lessons learned from the COVID pandemic and its impact on bioanalysis and drug development

Bioanalysis, 2021-06

2021

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A Dual-Monoclonal Sandwich ELISA Specific for Hepcidin-25

Clinical chemistry (Baltimore, Md.), 2010-11, Vol.56 (11), p.1725-1732

2010

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Engineered FcRn Binding Fusion Peptides Significantly Enhance the Half‐Life of a Fab Domain in Cynomolgus Monkeys

Biotechnology journal, 2019-03, Vol.14 (3), p.e1800007-n/a

2019

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Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose

Drug metabolism and disposition, 2015-10, Vol.43 (10), p.1477-1483

2015

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Growth differentiation factor 15 in anaemia of chronic disease, iron deficiency anaemia and mixed type anaemia

British journal of haematology, 2010-02, Vol.148 (3), p.449-455

2010

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Behavioral, biochemical, and genetic analysis of iron metabolism in high-intensity blood donors

Transfusion (Philadelphia, Pa.), 2008-10, Vol.48 (10), p.2197-2204

2008

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Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery

Current topics in medicinal chemistry, 2002-01, Vol.2 (1), p.53-66

2002

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High-throughput chromatographic approaches to liquid chromatographic/tandem mass spectrometric bioanalysis to support drug discovery and development

Analytica Chimica Acta, 2004-04, Vol.509 (1), p.1-9

2004

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Effects of flow rate on high-throughput quantitative analysis of protein-precipitated plasma using liquid chromatography/tandem mass spectrometry

Rapid communications in mass spectrometry, 2002-01, Vol.16 (6), p.537-543

2002

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Development of an Ion-Pair Reverse-Phase Liquid Chromatographic/Tandem Mass Spectrometry Method for the Determination of an 18-Mer Phosphorothioate Oligonucleotide in Mouse Liver Tissue

European journal of mass spectrometry (Chichester, England), 2005-01, Vol.11 (2), p.209-215

2005

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Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

The Journal of pharmacology and experimental therapeutics, 1999-04, Vol.289 (1), p.85

1999

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Superdonors Have Decreased Iron Stores but Can Repeatedly Donate Whole Blood through Use of Iron Supplements and Decreased Serum Hepcidin Concentration

Blood, 2007-11, Vol.110 (11), p.2887-2887

2007

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An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma

Journal of lipid research, 2008-03, Vol.49 (3), p.581

2008

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Advances in High Throughput Quantitative Drug Discovery Bioanalysis

Integrated Strategies for Drug Discovery Using Mass Spectrometry, 2005, p.315-358

2005

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A Novel Virus Causes Scale Drop Disease in Lates calcarifer

PLoS pathogens, 2015-08, Vol.11 (8), p.e1005074-e1005074

2015

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Reducing target binding affinity improves the therapeutic index of anti-MET antibody-drug conjugate in tumor bearing animals

Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

High-fat diet causes iron deficiency via hepcidin-independent reduction of duodenal iron absorption

Quantitation of hepcidin from human and mouse serum using liquid chromatography tandem mass spectrometry

Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency

An apolipoprotein A-I mimetic dose-dependently increases the formation of preβ1 HDL in human plasma

Lessons learned from the COVID-19 pandemic and its impact on bioanalysis and drug development

Lessons learned from the COVID pandemic and its impact on bioanalysis and drug development

A Dual-Monoclonal Sandwich ELISA Specific for Hepcidin-25

Engineered FcRn Binding Fusion Peptides Significantly Enhance the Half‐Life of a Fab Domain in Cynomolgus Monkeys

Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose

Growth differentiation factor 15 in anaemia of chronic disease, iron deficiency anaemia and mixed type anaemia

Behavioral, biochemical, and genetic analysis of iron metabolism in high-intensity blood donors

Recent advances in use of LC/MS/MS for quantitative high-throughput bioanalytical support of drug discovery

High-throughput chromatographic approaches to liquid chromatographic/tandem mass spectrometric bioanalysis to support drug discovery and development

Effects of flow rate on high-throughput quantitative analysis of protein-precipitated plasma using liquid chromatography/tandem mass spectrometry

Development of an Ion-Pair Reverse-Phase Liquid Chromatographic/Tandem Mass Spectrometry Method for the Determination of an 18-Mer Phosphorothioate Oligonucleotide in Mouse Liver Tissue

Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters

Superdonors Have Decreased Iron Stores but Can Repeatedly Donate Whole Blood through Use of Iron Supplements and Decreased Serum Hepcidin Concentration

An apolipoprotein A-I mimetic dose-dependently increases the formation of prebeta1 HDL in human plasma

Advances in High Throughput Quantitative Drug Discovery Bioanalysis

A Novel Virus Causes Scale Drop Disease in Lates calcarifer

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