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Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

Blood, 2010-06, Vol.115 (25), p.5241-5248

2010

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Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes

Nature biotechnology, 2003-08, Vol.21 (8), p.891-896

2003

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Cerebrovascular Thromboprophylaxis in Mice by Erythrocyte-Coupled Tissue-Type Plasminogen Activator

Circulation (New York, N.Y.), 2008-09, Vol.118 (14), p.1442-1449

2008

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Pro-thrombotic State Induced by Post-translational Modification of Fibrinogen by Reactive Nitrogen Species

The Journal of biological chemistry, 2004-03, Vol.279 (10), p.8820-8826

2004

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Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress

American Journal of Physiology: Cell Physiology, 2003-11, Vol.285 (5), p.C1339-C1347

2003

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The glycocalyx protects erythrocyte-bound tissue-type plasminogen activator from enzymatic inhibition

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.158-164

2007

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Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature

Blood, 2008-02, Vol.111 (4), p.1999-2006

2008

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Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia

American journal of physiology. Lung cellular and molecular physiology, 2006-11, Vol.291 (5), p.L1050-L1058

2006

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Fibrin affinity of erythrocyte-coupled tissue-type plasminogen activators endures hemodynamic forces and enhances fibrinolysis in vivo

The Journal of pharmacology and experimental therapeutics, 2006-03, Vol.316 (3), p.1130-1136

2006

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Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile

Journal of controlled release, 2009-11, Vol.139 (3), p.190-196

2009

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Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature

The Journal of pharmacology and experimental therapeutics, 2002-03, Vol.300 (3), p.777-786

2002

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Cell‐selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting

The FASEB journal, 2001-02, Vol.15 (2), p.416-426

2001

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Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis

The Journal of pharmacology and experimental therapeutics, 2010-03, Vol.332 (3), p.1022-1031

2010

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Human complement receptor type 1–directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysis

Blood, 2006-09, Vol.108 (6), p.1895-1902

2006

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tPA regulates pulmonary vascular activity through NMDA receptors

American journal of physiology. Lung cellular and molecular physiology, 2011-09, Vol.301 (3), p.L307-L314

2011

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Blood clearance and activity of erythrocyte-coupled fibrinolytics

The Journal of pharmacology and experimental therapeutics, 2005-03, Vol.312 (3), p.1106-1113

2005

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ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface

Blood, 2003-05, Vol.101 (10), p.3977-3984

2003

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Vascular Immunotargeting to Endothelial Surface in a Specific Macrodomain in Alveolar Capillaries

American journal of respiratory and critical care medicine, 2001-10, Vol.164 (7), p.1295-1302

2001

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Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets

Blood, 2003-08, Vol.102 (3), p.926-933

2003

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Characterization of endothelial internalization and targeting of antibody-enzyme conjugates in cell cultures and in laboratory animals

Methods in molecular biology (Clifton, N.J.), 2004, Vol.283, p.21

2004

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Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury : Targeting to Thrombomodulin, But Not to PECAM-1, Causes Pulmonary Thrombosis and Neutrophil Transmigration

The American journal of pathology, 2002-03, Vol.160 (3), p.1155-1169

2002

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Platelets inhibit the lysis of pulmonary microemboli

American journal of physiology. Lung cellular and molecular physiology, 2002-03, Vol.282 (3), p.529-L539

2002

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Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress

American Journal of Physiology: Cell Physiology, 2003-11, Vol.54 (5), p.C1339-C1347

2003

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Platelets inhibit the lysis of pulmonary microemboli

American journal of physiology. Lung cellular and molecular physiology, 2002-03, Vol.26 (3), p.L529-L539

2002

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Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury

The American journal of pathology, 2002-03, Vol.160 (3), p.1155-1169

2002

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Sustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation

Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes

Cerebrovascular Thromboprophylaxis in Mice by Erythrocyte-Coupled Tissue-Type Plasminogen Activator

Pro-thrombotic State Induced by Post-translational Modification of Fibrinogen by Reactive Nitrogen Species

Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress

The glycocalyx protects erythrocyte-bound tissue-type plasminogen activator from enzymatic inhibition

Prophylactic thrombolysis by thrombin-activated latent prourokinase targeted to PECAM-1 in the pulmonary vasculature

Dissociation between alveolar transmigration of neutrophils and lung injury in hyperoxia

Fibrin affinity of erythrocyte-coupled tissue-type plasminogen activators endures hemodynamic forces and enhances fibrinolysis in vivo

Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile

Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature

Cell‐selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting

Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis

Human complement receptor type 1–directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysis

tPA regulates pulmonary vascular activity through NMDA receptors

Blood clearance and activity of erythrocyte-coupled fibrinolytics

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface

Vascular Immunotargeting to Endothelial Surface in a Specific Macrodomain in Alveolar Capillaries

Antithrombotic thrombocytes: ectopic expression of urokinase-type plasminogen activator in platelets

Characterization of endothelial internalization and targeting of antibody-enzyme conjugates in cell cultures and in laboratory animals

Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury : Targeting to Thrombomodulin, But Not to PECAM-1, Causes Pulmonary Thrombosis and Neutrophil Transmigration

Platelets inhibit the lysis of pulmonary microemboli

Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress

Platelets inhibit the lysis of pulmonary microemboli

Vascular Immunotargeting of Glucose Oxidase to the Endothelial Antigens Induces Distinct Forms of Oxidant Acute Lung Injury

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