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Ras Conformational Ensembles, Allostery, and Signaling

Chemical reviews, 2016-06, Vol.116 (11), p.6607-6665

2016

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Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers

Biochemical journal, 2016-06, Vol.473 (12), p.1719-1732

2016

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Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation

eLife, 2020-03, Vol.9

2020

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A fluorescence‐based sensor for calibrated measurement of protein kinase stability in live cells

Protein science, 2024-06, Vol.33 (6), p.e5023-n/a

2024

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The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

Molecular cancer research, 2015-09, Vol.13 (9), p.1265-1273

2015

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Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

PloS one, 2020-01, Vol.15 (1), p.e0227520

2020

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Breakage of the oligomeric CaMKII hub by the regulatory segment of the kinase

eLife, 2020-09, Vol.9

2020

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The structural network of Interleukin-10 and its implications in inflammation and cancer

BMC genomics, 2014-05, Vol.15 Suppl 4 (S4), p.S2-S2, Article S2

2014

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Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

PloS one, 2021-08, Vol.16 (8), p.e0256640

2021

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PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization

The journal of physical chemistry. B, 2017-06, Vol.121 (24), p.5917-5927

2017

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GTP-Dependent K-Ras Dimerization

Structure (London), 2015-07, Vol.23 (7), p.1325-1335

2015

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Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

Proceedings of the National Academy of Sciences - PNAS, 2022-10, Vol.119 (40), p.e2210990119

2022

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Advances in template-based protein docking by utilizing interfaces towards completing structural interactome

Current opinion in structural biology, 2015-12, Vol.35, p.87-92

2015

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Overcoming clinical BCR-ABL1 compound mutant resistance with combined ponatinib and asciminib therapy

Cancer cell, 2024-09, Vol.42 (9), p.1486-1488

2024

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K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?

Expert opinion on therapeutic targets, 2016-07, Vol.20 (7), p.831-842

2016

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Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling

Journal of molecular biology, 2020-02, Vol.432 (4), p.1199-1215

2020

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Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation

Expert review of proteomics, 2015-11, Vol.12 (6), p.669-682

2015

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Drug discovery targeting SARS-CoV-2 membrane fusion

Biophysical journal, 2023-02, Vol.122 (3), p.322a-322a

2023

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Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP

Biophysical journal, 2015-09, Vol.109 (6), p.1227-1239

2015

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Plasma membrane regulates Ras signaling networks

Cellular logistics, 2015-10, Vol.5 (4), p.e1136374-e1136374

2015

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Elucidating Structural Details of Ras-Effector Interactions

International Journal of Advances in Engineering and Pure Sciences, 2019-03, Vol.31 (1), p.90-99

2019

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Interaction of the MR and GR in the nucleus and at DNA

Endocrine Abstracts, 2015-10

2015

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Ras Conformational Ensembles, Allostery, and Signaling

Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers

Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation

A fluorescence‐based sensor for calibrated measurement of protein kinase stability in live cells

The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Breakage of the oligomeric CaMKII hub by the regulatory segment of the kinase

The structural network of Interleukin-10 and its implications in inflammation and cancer

Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization

GTP-Dependent K-Ras Dimerization

Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

Advances in template-based protein docking by utilizing interfaces towards completing structural interactome

Overcoming clinical BCR-ABL1 compound mutant resistance with combined ponatinib and asciminib therapy

K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?

Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling

Principles of K-Ras effector organization and the role of oncogenic K-Ras in cancer initiation through G1 cell cycle deregulation

Drug discovery targeting SARS-CoV-2 membrane fusion

Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP

Plasma membrane regulates Ras signaling networks

Elucidating Structural Details of Ras-Effector Interactions

Interaction of the MR and GR in the nucleus and at DNA

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