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PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems

PLoS computational biology, 2018-02, Vol.14 (2), p.e1005991-e1005991

2018

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MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids

Journal of the American Society for Mass Spectrometry, 2018-03, Vol.29 (3), p.516-526

2018

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Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer

Nature communications, 2023-04, Vol.14 (1), p.2140-2140, Article 2140

2023

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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Clinical and translational science, 2021-09, Vol.14 (5), p.1659-1680

2021

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A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice

Nature communications, 2019-12, Vol.10 (1), p.5681-19, Article 5681

2019

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Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach

Scientific reports, 2021-01, Vol.11 (1), p.1710-1710, Article 1710

2021

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A high-content image-based method for quantitatively studying context-dependent cell population dynamics

Scientific reports, 2016-07, Vol.6 (1), p.29752, Article 29752

2016

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Leveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid Tumors

PLoS computational biology, 2016-08, Vol.12 (8), p.e1005077-e1005077

2016

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VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

Molecular oncology, 2021-10, Vol.15 (10), p.2801-2817

2021

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Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance

Cancers, 2020-05, Vol.12 (6), p.1393

2020

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Imaging-Based Machine Learning Analysis of Patient-Derived Tumor Organoid Drug Response

Frontiers in oncology, 2021-12, Vol.11, p.771173-771173

2021

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Multiplexed imaging and effluent analysis to monitor cancer cell intravasation using a colorectal cancer-on-chip

STAR protocols, 2021-12, Vol.2 (4), p.100984-100984, Article 100984

2021

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Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes

Molecular cancer therapeutics, 2009-10, Vol.8 (10), p.2882-2893

2009

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A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models

SLAS discovery, 2024-06, Vol.29 (4), p.100163-100163, Article 100163

2024

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Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

iScience, 2021-05, Vol.24 (5), p.102509-102509, Article 102509

2021

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Predictive Modeling of Drug Response in Non-Hodgkin's Lymphoma

PloS one, 2015-06, Vol.10 (6), p.e0129433

2015

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Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

Journal for immunotherapy of cancer, 2020-11, Vol.8 (2), p.e001714

2020

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Organs-on-chips: a decade of innovation

Trends in biotechnology (Regular ed.), 2023-03, Vol.41 (3), p.278-280

2023

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The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

Cancer informatics, 2015-01, Vol.2015 (Suppl. 4), p.19-31

2015

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CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value

Journal for immunotherapy of cancer, 2024-01, Vol.12 (1), p.e007939

2024

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Evolutionary Modeling of Combination Treatment Strategies To Overcome Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

Molecular pharmaceutics, 2011-12, Vol.8 (6), p.2069-2079

2011

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Donepezil and flight simulator performance: effects on retention of complex skills

Neurology, 2002-07, Vol.59 (1), p.123

2002

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Clocking cancer: the circadian clock as a target in cancer therapy

Oncogene, 2021-05, Vol.40 (18), p.3187-3200

2021

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Understanding patient-derived tumor organoid growth through an integrated imaging and mathematical modeling framework

PLoS computational biology, 2024-08, Vol.20 (8), p.e1012256

2024

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MALDI-MSI of Immunotherapy: Mapping the EGFR-Targeting Antibody Cetuximab in 3D Colon-Cancer Cell Cultures

Analytical chemistry (Washington), 2018-12, Vol.90 (24), p.14156-14164

2018

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PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems

MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids

Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice

Impact of tumor-parenchyma biomechanics on liver metastatic progression: a multi-model approach

A high-content image-based method for quantitatively studying context-dependent cell population dynamics

Leveraging Hypoxia-Activated Prodrugs to Prevent Drug Resistance in Solid Tumors

VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance

Imaging-Based Machine Learning Analysis of Patient-Derived Tumor Organoid Drug Response

Multiplexed imaging and effluent analysis to monitor cancer cell intravasation using a colorectal cancer-on-chip

Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes

A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip models

Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread

Predictive Modeling of Drug Response in Non-Hodgkin's Lymphoma

Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer

Organs-on-chips: a decade of innovation

The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells

CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value

Evolutionary Modeling of Combination Treatment Strategies To Overcome Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

Donepezil and flight simulator performance: effects on retention of complex skills

Clocking cancer: the circadian clock as a target in cancer therapy

Understanding patient-derived tumor organoid growth through an integrated imaging and mathematical modeling framework

MALDI-MSI of Immunotherapy: Mapping the EGFR-Targeting Antibody Cetuximab in 3D Colon-Cancer Cell Cultures

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