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Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Nucleic acids research, 2019-07, Vol.47 (12), p.6029

2019

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Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report

Arteriosclerosis, thrombosis, and vascular biology, 2016-09, Vol.36 (9), p.1753

2016

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Endothelial cell CD36 optimizes tissue fatty acid uptake

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4329-4342

2018

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Loss of Hepatic Angiotensinogen Attenuates Sepsis-Induced Myocardial Dysfunction

Circulation research, 2021-08, Vol.129 (5), p.547-564

2021

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ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

The Journal of clinical investigation, 2016-08, Vol.126 (8), p.2855-2866

2016

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Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

Circulation research, 2013-05, Vol.112 (11), p.1479-1490

2013

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In memoriam Dr Linda “Kirt” Curtiss

Journal of lipid research, 2021-01, Vol.62, p.100076, Article 100076

2021

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CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins

The Journal of clinical investigation, 2021-11, Vol.131 (22), p.1-16

2021

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Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report

Arteriosclerosis, thrombosis, and vascular biology, 2019-02, Vol.39 (2), p.150

2019

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(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis

Circulation research, 2018-03, Vol.122 (5), p.730-741

2018

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Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

Journal of lipid research, 2021-01, Vol.62, p.100101-100101, Article 100101

2021

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Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

The Journal of experimental medicine, 2008-02, Vol.205 (2), p.373-383

2008

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Antisense Oligonucleotide Lowers Plasma Levels of Apolipoprotein (a) and Lipoprotein (a) in Transgenic Mice

Journal of the American College of Cardiology, 2011-04, Vol.57 (15), p.1611-1621

2011

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Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice

Circulation (New York, N.Y.), 2008-08, Vol.118 (7), p.743-753

2008

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Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

Bioscience reports, 2019-01, Vol.39 (1), p.1

2019

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Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease

Pharmacological research, 2017-11, Vol.125 (Pt A), p.57-71

2017

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Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2427

2022

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A high fat diet does not stimulate blood pressure dependence on chemerin in the Sprague-Dawley rat

American heart journal plus, 2022-10, Vol.22, p.100205-100205, Article 100205

2022

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Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat

Biomedicines, 2022-07, Vol.10 (7), p.1635

2022

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Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

Journal of lipid research, 2013-03, Vol.54 (3), p.602-614

2013

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Chemerin as a Driver of Hypertension: A Consideration

American journal of hypertension, 2020-11, Vol.33 (11), p.975-986

2020

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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Nature immunology, 2013-08, Vol.14 (8), p.812

2013

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Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice[S]

Journal of lipid research, 2011-05, Vol.52 (5), p.885-896

2011

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Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering

JCI insight, 2022-07, Vol.7 (13)

2022

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Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice

Journal of lipid research, 2013-10, Vol.54 (10), p.2647-2657

2013

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Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle

Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report

Endothelial cell CD36 optimizes tissue fatty acid uptake

Loss of Hepatic Angiotensinogen Attenuates Sepsis-Induced Myocardial Dysfunction

ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

In memoriam Dr Linda “Kirt” Curtiss

CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins

Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report

(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis

Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events

Antisense Oligonucleotide Lowers Plasma Levels of Apolipoprotein (a) and Lipoprotein (a) in Transgenic Mice

Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice

Antisense oligonucleotides targeting angiotensinogen: insights from animal studies

Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease

Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation

A high fat diet does not stimulate blood pressure dependence on chemerin in the Sprague-Dawley rat

Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

Chemerin as a Driver of Hypertension: A Consideration

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice[S]

Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice

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