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Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer

Oncogene, 2009-12, Vol.28 (50), p.4409-4420

2009

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A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Nature, 2004-03, Vol.428 (6981), p.431-437

2004

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A Genetic Screen Identifies PITX1 as a Suppressor of RAS Activity and Tumorigenicity

Cell, 2005-06, Vol.121 (6), p.849-858

2005

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An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

Nature chemical biology, 2006-04, Vol.2 (4), p.202-206

2006

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Involvement of MINK, a Ste20 Family Kinase, in Ras Oncogene-Induced Growth Arrest in Human Ovarian Surface Epithelial Cells

Molecular cell, 2005-12, Vol.20 (5), p.673-685

2005

Volltextzugriff (PDF)

WS04-5 The TOPAZ study, a large-scale study in organoids derived from F508del homozygous cystic fibrosis patients treated with Orkambi

Journal of cystic fibrosis, 2019-06, Vol.18, p.S8-S8

2019

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ePS1.05 High reproducibility of Forskolin-induced swelling of intestinal organoids across three academic laboratories

Journal of cystic fibrosis, 2019-06, Vol.18, p.S40-S40

2019

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Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells

Cold Spring Harbor Symposia on Quantitative Biology, 2004, Vol.69, p.439-446

2004

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Perioperative management of diabetes in elective patients: a region-wide audit

British journal of anaesthesia : BJA, 2016-04, Vol.116 (4), p.501-506

2016

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A Homology Model for Rat Mu Class Glutathione S-Transferase 4-4

Chemical research in toxicology, 1996-01, Vol.9 (1), p.28-40

1996

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The core spliceosome as target and effector of non-canonical ATM signalling

Nature (London), 2015-07, Vol.523 (7558), p.53-58

2015

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Heterochromatin Protein 1 Is Recruited to Various Types of DNA Damage

The Journal of cell biology, 2009-05, Vol.185 (4), p.577-586

2009

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Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Nature cell biology, 2009-05, Vol.11 (5), p.604-615

2009

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Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo

Molecular cell, 2001-07, Vol.8 (1), p.213-224

2001

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Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action

Archives of toxicology, 2020-05, Vol.94 (5), p.1655-1671

2020

Volltextzugriff (PDF)

Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair

Human molecular genetics, 2007-06, Vol.16 (12), p.1478-1487

2007

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Altered association of transcriptionally active DNA with the nuclear-matrix after heat shock

International journal of radiation biology, 1999, Vol.75 (7), p.875-883

1999

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PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

The Journal of cell biology, 2012-10, Vol.199 (2), p.235-249

2012

Volltextzugriff (PDF)

The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest

Molecular and cellular biology, 2015-04, Vol.35 (7), p.1254-1268

2015

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Local UV-induced DNA damage in cell nuclei results in local transcription inhibition

EMBO reports, 2001-11, Vol.2 (11), p.1013-1017

2001

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Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3794

2022

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TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Nature communications, 2018-03, Vol.9 (1), p.1040-14, Article 1040

2018

Volltextzugriff (PDF)

Global Phosphoproteome Profiling Reveals Unanticipated Networks Responsive to Cisplatin Treatment of Embryonic Stem Cells

Molecular and Cellular Biology, 2011-12, Vol.31 (24), p.4964-4977

2011

Volltextzugriff (PDF)

Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation

Cancer research (Chicago, Ill.), 2005-11, Vol.65 (22), p.10298-10306

2005

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Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

The Journal of experimental medicine, 2010-02, Vol.207 (2), p.379-390

2010

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Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

A Genetic Screen Identifies PITX1 as a Suppressor of RAS Activity and Tumorigenicity

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

Involvement of MINK, a Ste20 Family Kinase, in Ras Oncogene-Induced Growth Arrest in Human Ovarian Surface Epithelial Cells

WS04-5 The TOPAZ study, a large-scale study in organoids derived from F508del homozygous cystic fibrosis patients treated with Orkambi

ePS1.05 High reproducibility of Forskolin-induced swelling of intestinal organoids across three academic laboratories

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells

Perioperative management of diabetes in elective patients: a region-wide audit

A Homology Model for Rat Mu Class Glutathione S-Transferase 4-4

The core spliceosome as target and effector of non-canonical ATM signalling

Heterochromatin Protein 1 Is Recruited to Various Types of DNA Damage

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Sequential Assembly of the Nucleotide Excision Repair Factors In Vivo

Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action

Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair

Altered association of transcriptionally active DNA with the nuclear-matrix after heat shock

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

The E3 Ubiquitin Ligase ARIH1 Protects against Genotoxic Stress by Initiating a 4EHP-Mediated mRNA Translation Arrest

Local UV-induced DNA damage in cell nuclei results in local transcription inhibition

Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Global Phosphoproteome Profiling Reveals Unanticipated Networks Responsive to Cisplatin Treatment of Embryonic Stem Cells

Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

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