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MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion

Clinical cancer research, 2019-08, Vol.25 (16), p.5107-5121

2019

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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

Immunity (Cambridge, Mass.), 2018-10, Vol.49 (4), p.764-779.e9

2018

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Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy

Gene therapy, 2019-02, Vol.26 (1-2), p.1-15

2019

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Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

Cell reports (Cambridge), 2014-07, Vol.8 (1), p.40-49

2014

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Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis

Journal of cellular physiology, 2006-08, Vol.208 (2), p.336-343

2006

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Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity

Molecular therapy. Oncolytics, 2022-06, Vol.25, p.174-188

2022

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Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling

Journal of investigative dermatology, 2011-02, Vol.131 (2), p.311-319

2011

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The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair

PloS one, 2011-11, Vol.6 (11), p.e27603-e27603

2011

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Abstract 3195: Intratumoral electroporation of plasmid IL-12 and CXCL9 with membrane-bound anti-CD3 elicits robust anti-tumor immunity

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3195-3195

2019

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Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

Nature communications, 2018-09, Vol.9 (1), p.3787-11, Article 3787

2018

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Abstract PR05: Lineage specifiers SOX2 and NKX2-1 inversely regulate lung tumor immune microenvironment

Cancer research (Chicago, Ill.), 2018-05, Vol.78 (10_Supplement), p.PR05-PR05

2018

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Abstract 5617: Combined intratumoral electroporation and allogeneic vaccination of Gp96-Ig/Fc-OX40L stimulates CD8 T cell cross-priming to tumor specific neoantigens and enhanced anti-tumor response

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5617-5617

2017

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Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity

Molecular cancer research, 2022-06, Vol.20 (6), p.983-995

2022

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Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells

Journal of investigative dermatology, 2008-03, Vol.128 (3), p.702-709

2008

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Abstract LB-396: Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of CXCL9 synergizes with IL-12 gene therapy (TAVO) to elicit robust anti-tumor immunity

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.LB-396-LB-396

2020

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Abstract LB-390: Intratumoral electroporation of plasmid-encoded IL-12 and membrane-bound anti-CD3 increases tumor immunogenicity and augments the function of T cell subsets

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.LB-390-LB-390

2020

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Sox2 cooperates with Lkb1 loss to promote squamous cell lung cancer

Journal of thoracic oncology, 2016-02, Vol.11 (2), p.S11-S11

2016

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1427 Comparative analysis of human immune subsets and Rituximab antitumor response across multiple NSG strains engrafted with human hematopoietic stem cells

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A1485-A1485

2022

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Abstract 1614: Intratumoral delivery of a P2A-linked bicistronic IL-12 construct leads to high intratumoral expression and systemic anti-tumor response

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1614-1614

2017

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Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development

Developmental biology, 2013-01, Vol.373 (2), p.373-382

2013

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Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid)

Immunotherapy, 2017-12, Vol.9 (16), p.1309-1321

2017

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Development of an adaptive electroporation system for intratumoral plasmid DNA delivery

Bioelectrochemistry (Amsterdam, Netherlands), 2018-08, Vol.122, p.191-198

2018

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Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model

Cancer Immunology, Immunotherapy, 2019-08, Vol.68 (8), p.1273-1286

2019

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Skin and hair: models for exploring organ regeneration

Human molecular genetics, 2008-04, Vol.17 (R1), p.R54-R59

2008

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MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

Characterization of abscopal effects of intratumoral electroporation-mediated IL-12 gene therapy

Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis

Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity

Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling

The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair

MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition

Abstract 3195: Intratumoral electroporation of plasmid IL-12 and CXCL9 with membrane-bound anti-CD3 elicits robust anti-tumor immunity

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

Abstract PR05: Lineage specifiers SOX2 and NKX2-1 inversely regulate lung tumor immune microenvironment

Abstract 5617: Combined intratumoral electroporation and allogeneic vaccination of Gp96-Ig/Fc-OX40L stimulates CD8 T cell cross-priming to tumor specific neoantigens and enhanced anti-tumor response

Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity

Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells

Abstract LB-396: Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of CXCL9 synergizes with IL-12 gene therapy (TAVO) to elicit robust anti-tumor immunity

Abstract LB-390: Intratumoral electroporation of plasmid-encoded IL-12 and membrane-bound anti-CD3 increases tumor immunogenicity and augments the function of T cell subsets

Sox2 cooperates with Lkb1 loss to promote squamous cell lung cancer

1427 Comparative analysis of human immune subsets and Rituximab antitumor response across multiple NSG strains engrafted with human hematopoietic stem cells

Abstract 1614: Intratumoral delivery of a P2A-linked bicistronic IL-12 construct leads to high intratumoral expression and systemic anti-tumor response

Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development

Melanoma treatment with intratumoral electroporation of tavokinogene telseplasmid (pIL-12, tavokinogene telseplasmid)

Development of an adaptive electroporation system for intratumoral plasmid DNA delivery

Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model

Skin and hair: models for exploring organ regeneration

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