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The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus

PloS one, 2013-03, Vol.8 (3), p.e60394

2013

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A Peptide Based on the Complementarity-Determining Region 1 of an Autoantibody Ameliorates Lupus by up-Regulating CD4⁺CD25⁺ cells and TGF-β

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (23), p.8810-8815

2006

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Therapeutic Vaccines in Autoimmunity

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (Suppl 2), p.14586-14592

2004

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In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice

PloS one, 2009-12, Vol.4 (12), p.e8447-e8447

2009

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The Suppression of Murine Lupus by a Tolerogenic Peptide Involves Foxp3-Expressing CD8 Cells That Are Required for the Optimal Induction and Function of Foxp3-Expressing CD4 Cells

The Journal of immunology (1950), 2008-09, Vol.181 (5), p.3243-3251

2008

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Prof. Michael Sela (1924–2022)

European journal of immunology, 2022-10, Vol.52 (10), p.1539-1540

2022

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Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus

Journal of autoimmunity, 2014-11, Vol.54, p.60-71

2014

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The Mechanism by which a Peptide Based on Complementarity-Determining Region-1 of a Pathogenic Anti-DNA Auto-Ab Ameliorates Experimental Systemic Lupus Erythematosus

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (3), p.1148-1153

2001

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A Dual Altered Peptide Ligand Down-Regulates Myasthenogenic T Cell Responses by Up-Regulating CD25- and CTLA-4-Expressing CD4+T Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-05, Vol.100 (11), p.6676-6681

2003

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A 50-KDa ERK-Like Protein Is Up-Regulated by a Dual Altered Peptide Ligand That Suppresses Myasthenia Gravis-Associated Responses

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (48), p.18232-18237

2006

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The Nature of the Active Suppression of Responses Associated with Experimental Autoimmune Myasthenia Gravis by a Dual Altered Peptide Ligand Administered by Different Routes

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (22), p.12642-12647

2001

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A novel tolerogenic peptide, hCDR1, for the specific treatment of systemic lupus erythematosus

Autoimmunity reviews, 2010-11, Vol.10 (1), p.22-26

2010

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Down-Regulation of Myasthenogenic T Cell Responses by a Dual Altered Peptide Ligand via CD4+CD25+-Regulated Events Leading to Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (6), p.2028-2033

2005

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Indoleamine-2,3-dioxygenase in murine and human systemic lupus erythematosus: Down-regulation by the tolerogeneic peptide hCDR1

Clinical immunology (Orlando, Fla.), 2018-12, Vol.197, p.34-39

2018

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role of CD8⁺CD28⁻ regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17459-17464

2007

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Suppression of Myasthenogenic Responses of a T Cell Line by a Dual Altered Peptide Ligand by Induction of CD4+CD25+Regulatory Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (29), p.10285-10290

2005

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The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients

Clinical immunology (Orlando, Fla.), 2018-07, Vol.192, p.85-91

2018

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Bcl-xL affects the development of functional CD4 Tregs

Arthritis research & therapy, 2010-01, Vol.12 (4), p.405-405

2010

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Bcl-xL is required for the development of functional regulatory CD4 cells in lupus-afflicted mice following treatment with a tolerogenic peptide

Journal of autoimmunity, 2010-03, Vol.34 (2), p.87-95

2010

Volltextzugriff (PDF)

Modulation of Murine Systemic Lupus Erythematosus with Peptides Based on Complementarity Determining Regions of a Pathogenic Anti-DNA Monoclonal Antibody

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (9), p.4620-4625

1997

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Oral Administration of a Dual Analog of Two Myasthenogenic T Cell Epitopes down-Regulates Experimental Autoimmune Myasthenia Gravis in Mice

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (5), p.2168-2173

2000

Volltextzugriff (PDF)

The Tolerogenic Peptide, hCDR1, Down-Regulates the Expression of Interferon-[alpha] in Murine and Human Systemic Lupus Erythematosus

PloS one, 2013-03, Vol.8 (3), p.e60394

2013

Volltextzugriff (PDF)

Characteristics and pathogenic role of anti-β2-glycoprotein I single-chain Fv domains: induction of experimental antiphospholipid syndrome

International immunology, 1999-12, Vol.11 (12), p.1917-1926

1999

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Induction of hippocampal neurogenesis by a tolerogenic peptide that ameliorates lupus manifestations

Journal of neuroimmunology, 2011-03, Vol.232 (1), p.151-157

2011

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T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency

The journal of clinical endocrinology and metabolism, 2009-12, Vol.94 (12), p.5117-5124

2009

Volltextzugriff (PDF)

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The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus

A Peptide Based on the Complementarity-Determining Region 1 of an Autoantibody Ameliorates Lupus by up-Regulating CD4⁺CD25⁺ cells and TGF-β

Therapeutic Vaccines in Autoimmunity

In vivo dynamical interactions between CD4 Tregs, CD8 Tregs and CD4+ CD25- cells in mice

The Suppression of Murine Lupus by a Tolerogenic Peptide Involves Foxp3-Expressing CD8 Cells That Are Required for the Optimal Induction and Function of Foxp3-Expressing CD4 Cells

Prof. Michael Sela (1924–2022)

Novel approaches to the development of targeted therapeutic agents for systemic lupus erythematosus

The Mechanism by which a Peptide Based on Complementarity-Determining Region-1 of a Pathogenic Anti-DNA Auto-Ab Ameliorates Experimental Systemic Lupus Erythematosus

A Dual Altered Peptide Ligand Down-Regulates Myasthenogenic T Cell Responses by Up-Regulating CD25- and CTLA-4-Expressing CD4+T Cells

A 50-KDa ERK-Like Protein Is Up-Regulated by a Dual Altered Peptide Ligand That Suppresses Myasthenia Gravis-Associated Responses

The Nature of the Active Suppression of Responses Associated with Experimental Autoimmune Myasthenia Gravis by a Dual Altered Peptide Ligand Administered by Different Routes

A novel tolerogenic peptide, hCDR1, for the specific treatment of systemic lupus erythematosus

Down-Regulation of Myasthenogenic T Cell Responses by a Dual Altered Peptide Ligand via CD4+CD25+-Regulated Events Leading to Apoptosis

Indoleamine-2,3-dioxygenase in murine and human systemic lupus erythematosus: Down-regulation by the tolerogeneic peptide hCDR1

role of CD8⁺CD28⁻ regulatory cells in suppressing myasthenia gravis-associated responses by a dual altered peptide ligand

Suppression of Myasthenogenic Responses of a T Cell Line by a Dual Altered Peptide Ligand by Induction of CD4+CD25+Regulatory Cells

The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients

Bcl-xL affects the development of functional CD4 Tregs

Bcl-xL is required for the development of functional regulatory CD4 cells in lupus-afflicted mice following treatment with a tolerogenic peptide

Modulation of Murine Systemic Lupus Erythematosus with Peptides Based on Complementarity Determining Regions of a Pathogenic Anti-DNA Monoclonal Antibody

Oral Administration of a Dual Analog of Two Myasthenogenic T Cell Epitopes down-Regulates Experimental Autoimmune Myasthenia Gravis in Mice

The Tolerogenic Peptide, hCDR1, Down-Regulates the Expression of Interferon-[alpha] in Murine and Human Systemic Lupus Erythematosus

Characteristics and pathogenic role of anti-β2-glycoprotein I single-chain Fv domains: induction of experimental antiphospholipid syndrome

Induction of hippocampal neurogenesis by a tolerogenic peptide that ameliorates lupus manifestations

T Cell Responses to Steroid Cytochrome P450 21-Hydroxylase in Patients with Autoimmune Primary Adrenal Insufficiency

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