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Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP

The Journal of physiology, 2020-11, Vol.598 (22), p.5165-5182

2020

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Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment

Aging cell, 2020-02, Vol.19 (2), p.e13086-n/a

2020

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Contractile properties of developing human fetal cardiac muscle

The Journal of physiology, 2016-01, Vol.594 (2), p.437-452

2016

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Translation of Cardiac Myosin Activation With 2-Deoxy-ATP to Treat Heart Failure Via an Experimental Ribonucleotide Reductase-Based Gene Therapy

JACC. Basic to translational science, 2016-12, Vol.1 (7), p.666-679

2016

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Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

JCI insight, 2020-10, Vol.5 (20)

2020

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Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate

JACC. Basic to translational science, 2019-11, Vol.4 (7), p.778-791

2019

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An optimized and simplified system of mouse embryonic stem cell cardiac differentiation for the assessment of differentiation modifiers

PloS one, 2014-03, Vol.9 (3), p.e93033-e93033

2014

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Viral-Mediated Gene Transfer to Mouse Primary Neural Progenitor Cells

Molecular therapy, 2002-01, Vol.5 (1), p.16-24

2002

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Gene Therapy for Nonischemic Cardiomyopathy: Moving Forward by Learning From Lessons of the Past

Journal of the American College of Cardiology, 2017-10, Vol.70 (14), p.1757-1759

2017

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Gene Therapy for Nonischemic Cardiomyopathy

Journal of the American College of Cardiology, 2017-10, Vol.70 (14), p.1757-1759

2017

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The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility

Biophysical journal, 2024-02, Vol.123 (3), p.266a-267a

2024

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Estimating the effect of danicamtiv on human cardiac function

Biophysical journal, 2024-02, Vol.123 (3), p.266a-266a

2024

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Simulating Cardiac Muscle Mutations in a Compliant Lattice with Commonly Used Assays

Biophysical journal, 2021-02, Vol.120 (3), p.250a-250a

2021

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Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations

Biophysical journal, 2024-02, Vol.123 (3), p.401a-402a

2024

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Abstract 911: New Promoters to Improve the Efficiency of Cardiac Gene Therapies Using 2 Deoxy-ATP

Circulation research, 2019-08, Vol.125 (Suppl_1)

2019

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Predicting underlying pathology in simulated cardiac muscle twitches

Biophysical journal, 2022-02, Vol.121 (3), p.380a-380a

2022

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Ribonucleotide reductase mediated regulation of mitochondrial activity in the adult heart

Biophysical journal, 2022-02, Vol.121 (3), p.396a-397a

2022

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DeoxyATP producing hiPSC derived cardiomyocyte to restore cardiac function in heart failure

Biophysical journal, 2022-02, Vol.121 (3), p.254a-254a

2022

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The biochemically defined super relaxed state of myosin-A paradox

The Journal of biological chemistry, 2024-01, Vol.300 (1), p.105565-105565, Article 105565

2024

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Hipsc Derived Cardiomyocytes Overexpressing Deoxy ATP to Restore Cardiac Function in Myocardial Infarction

Biophysical journal, 2021-02, Vol.120 (3), p.104a-104a

2021

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The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy

Biophysical journal, 2023-02, Vol.122 (3), p.121a-122a

2023

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A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

Cell, 2016-05, Vol.165 (5), p.1147-1159

2016

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Effects of Oxidative Damage and Telomerase Activity on Human Articular Cartilage Chondrocyte Senescence

The journals of gerontology. Series A, Biological sciences and medical sciences, 2004-04, Vol.59 (4), p.B324-B336

2004

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Ribonucleotide Reductase is Essential in Adult Cardiomyocytes

Biophysical journal, 2020-02, Vol.118 (3), p.257a-257a

2020

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Machine learning meets Monte Carlo methods for models of muscle's molecular machinery to classify mutations

The Journal of general physiology, 2023-05, Vol.155 (5), p.1

2023

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Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP

Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment

Contractile properties of developing human fetal cardiac muscle

Translation of Cardiac Myosin Activation With 2-Deoxy-ATP to Treat Heart Failure Via an Experimental Ribonucleotide Reductase-Based Gene Therapy

Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts

Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate

An optimized and simplified system of mouse embryonic stem cell cardiac differentiation for the assessment of differentiation modifiers

Viral-Mediated Gene Transfer to Mouse Primary Neural Progenitor Cells

Gene Therapy for Nonischemic Cardiomyopathy: Moving Forward by Learning From Lessons of the Past

Gene Therapy for Nonischemic Cardiomyopathy

The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility

Estimating the effect of danicamtiv on human cardiac function

Simulating Cardiac Muscle Mutations in a Compliant Lattice with Commonly Used Assays

Molecular dynamics models demonstrate alterations in troponin’s function caused by cardiomyopathy-associated mutations

Abstract 911: New Promoters to Improve the Efficiency of Cardiac Gene Therapies Using 2 Deoxy-ATP

Predicting underlying pathology in simulated cardiac muscle twitches

Ribonucleotide reductase mediated regulation of mitochondrial activity in the adult heart

DeoxyATP producing hiPSC derived cardiomyocyte to restore cardiac function in heart failure

The biochemically defined super relaxed state of myosin-A paradox

Hipsc Derived Cardiomyocytes Overexpressing Deoxy ATP to Restore Cardiac Function in Myocardial Infarction

The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

Effects of Oxidative Damage and Telomerase Activity on Human Articular Cartilage Chondrocyte Senescence

Ribonucleotide Reductase is Essential in Adult Cardiomyocytes

Machine learning meets Monte Carlo methods for models of muscle's molecular machinery to classify mutations

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