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Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives

Current pharmaceutical design, 2004-04, Vol.10 (9), p.967

Mourão, Paulo A S

2004

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Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae

The Journal of biological chemistry, 1999-03, Vol.274 (12), p.7656-7667

1999

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A carbohydrate-based mechanism of species recognition in sea urchin fertilization

Brazilian journal of medical and biological research, 2007-01, Vol.40 (1), p.5-17

Mourao, PAS

2007

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Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

The Journal of biological chemistry, 2004-05, Vol.279 (20), p.20824-20835

2004

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Structural and hemostatic activities of a sulfated galactofucan from the brown alga Spatoglossum schroederi. An ideal antithrombotic agent?

The Journal of biological chemistry, 2005-12, Vol.280 (50), p.41278-41288

2005

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Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans?

Glycobiology (Oxford), 2002-10, Vol.12 (10), p.573-580

2002

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Structure and anticoagulant activity of sulfated galactans. Isolation of a unique sulfated galactan from the red algae Botryocladia occidentalis and comparison of its anticoagulant action with that of sulfated galactans from invertebrates

The Journal of biological chemistry, 2000-09, Vol.275 (38), p.29299-29307

2000

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Structure and anticoagulant activity of a sulfated galactan from the red alga, Gelidium crinale. Is there a specific structural requirement for the anticoagulant action?

Carbohydrate research, 2005-09, Vol.340 (12), p.2015-2023

2005

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Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity

Glycobiology (Oxford), 2005-04, Vol.15 (4), p.369-381

2005

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Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides

Glycobiology (Oxford), 2005-12, Vol.15 (12), p.1376-1385

2005

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Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant action

The Journal of biological chemistry, 1996-09, Vol.271 (39), p.23973-23984

1996

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Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities

Journal of molecular graphics & modelling, 2007-07, Vol.26 (1), p.391-399

2007

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Occurrence of sulfated galactans in marine angiosperms: evolutionary implications

Glycobiology (Oxford), 2005-01, Vol.15 (1), p.11-20

2005

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The structure of sulfated polysaccharides ensures a carbohydrate-based mechanism for species recognition during sea urchin fertilization

The International journal of developmental biology, 2008, Vol.52 (5-6), p.551

2008

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Searching for Alternatives to Heparin: Sulfated Fucans from Marine Invertebrates

Trends in Cardiovascular Medicine, 1999-11, Vol.9 (8), p.225-232

1999

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Structure/function studies of anticoagulant sulphated polysaccharides using NMR

Journal of biotechnology, 2000-01, Vol.77 (1), p.123-135

2000

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The nontoxic mushroom Auricularia auricula contains a polysaccharide with anticoagulant activity mediated by antithrombin

Thrombosis research, 2003, Vol.112 (3), p.151-158

2003

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Sulfated Fucans from the Egg Jellies of the Closely Related Sea Urchins Strongylocentrotus droebachiensis and Strongylocentrotus pallidus Ensure Species-specific Fertilization

The Journal of biological chemistry, 2002-01, Vol.277 (1), p.379-387

2002

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Ultrastructure of acidic polysaccharides from the cell walls of brown algae

Journal of structural biology, 2004-03, Vol.145 (3), p.216-225

2004

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Dermatan sulfate is the predominant antithrombotic glycosaminoglycan in vessel walls: Implications for a possible physiological function of heparin cofactor II

Biochimica et biophysica acta, 2005-04, Vol.1740 (1), p.45-53

2005

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Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans

Blood coagulation & fibrinolysis, 2004-01, Vol.15 (1), p.45-54

2004

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A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis

Molecular cancer research, 2002-12, Vol.1 (2), p.96-102

2002

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Highly sulfated dermatan sulfates from Ascidians. Structure versus anticoagulant activity of these glycosaminoglycans

The Journal of biological chemistry, 1998-10, Vol.273 (43), p.27848-27857

1998

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A 2-sulfated, 3-linked α- l-galactan is an anticoagulant polysaccharide

Carbohydrate research, 2002-11, Vol.337 (21), p.2231-2238

2002

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Antithrombotic activity of a fucosylated chondroitin sulphate from echinoderm: sulphated fucose branches on the polysaccharide account for its antithrombotic action

British journal of haematology, 1998-06, Vol.101 (4), p.647-652

1998

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Use of sulfated fucans as anticoagulant and antithrombotic agents: future perspectives

Structure and anticoagulant activity of sulfated fucans. Comparison between the regular, repetitive, and linear fucans from echinoderms with the more heterogeneous and branched polymers from brown algae

A carbohydrate-based mechanism of species recognition in sea urchin fertilization

Antithrombin-mediated anticoagulant activity of sulfated polysaccharides: different mechanisms for heparin and sulfated galactans

Structural and hemostatic activities of a sulfated galactofucan from the brown alga Spatoglossum schroederi. An ideal antithrombotic agent?

Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans?

Structure and anticoagulant activity of sulfated galactans. Isolation of a unique sulfated galactan from the red algae Botryocladia occidentalis and comparison of its anticoagulant action with that of sulfated galactans from invertebrates

Structure and anticoagulant activity of a sulfated galactan from the red alga, Gelidium crinale. Is there a specific structural requirement for the anticoagulant action?

Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity

Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides

Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant action

Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities

Occurrence of sulfated galactans in marine angiosperms: evolutionary implications

The structure of sulfated polysaccharides ensures a carbohydrate-based mechanism for species recognition during sea urchin fertilization

Searching for Alternatives to Heparin: Sulfated Fucans from Marine Invertebrates

Structure/function studies of anticoagulant sulphated polysaccharides using NMR

The nontoxic mushroom Auricularia auricula contains a polysaccharide with anticoagulant activity mediated by antithrombin

Sulfated Fucans from the Egg Jellies of the Closely Related Sea Urchins Strongylocentrotus droebachiensis and Strongylocentrotus pallidus Ensure Species-specific Fertilization

Ultrastructure of acidic polysaccharides from the cell walls of brown algae

Dermatan sulfate is the predominant antithrombotic glycosaminoglycan in vessel walls: Implications for a possible physiological function of heparin cofactor II

Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans

A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis

Highly sulfated dermatan sulfates from Ascidians. Structure versus anticoagulant activity of these glycosaminoglycans

A 2-sulfated, 3-linked α- l-galactan is an anticoagulant polysaccharide

Antithrombotic activity of a fucosylated chondroitin sulphate from echinoderm: sulphated fucose branches on the polysaccharide account for its antithrombotic action

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