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Molecular mechanisms of cell death in neurological diseases

Cell death and differentiation, 2021-07, Vol.28 (7), p.2029-2044

2021

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Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

CNS drugs, 2016-03, Vol.30 (3), p.227-243

2016

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The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

Cell death & disease, 2021-01, Vol.12 (1), p.133-133, Article 133

2021

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Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

Human molecular genetics, 2015-03, Vol.24 (6), p.1655-1669

2015

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Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

Nature communications, 2014-03, Vol.5 (1), p.3455-3455, Article 3455

2014

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Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

PloS one, 2013-06, Vol.8 (6), p.e67433

2013

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CuII(atsm) Attenuates Neuroinflammation

Frontiers in neuroscience, 2018-09, Vol.12, p.668-668

2018

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The PKA paradox: Is Bim the answer?

Cell cycle (Georgetown, Tex.), 2011-03, Vol.10 (5), p.729-730

2011

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Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Acta neuropathologica communications, 2014-02, Vol.2 (1), p.25-25, Article 25

2014

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TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Human molecular genetics, 2017-05, Vol.26 (9), p.1732-1746

2017

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The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

Cell death and differentiation, 2023-04, Vol.30 (4), p.1033-1046

2023

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BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Cell death and differentiation, 2022-07, Vol.29 (7), p.1335-1348

2022

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Metabolic Plasticity of Glioblastoma Cells in Response to DHODH Inhibitor BAY2402234 Treatment

Metabolites, 2024-07, Vol.14 (8), p.413

2024

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Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

Cell death and differentiation, 2023-04, Vol.30 (4), p.1096-1096

2023

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Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P‑Glycoprotein Mediated Efflux

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.711-723

2018

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Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

EMBO reports, 2011-01, Vol.12 (1), p.77-83

2011

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Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

Blood advances, 2023-04, Vol.7 (8), p.1560-1571

2023

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Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

Scientific reports, 2017-11, Vol.7 (1), p.14953-10, Article 14953

2017

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Cu II (atsm) Attenuates Neuroinflammation

Frontiers in neuroscience, 2018, Vol.12, p.668

2018

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Phosphorylation of hnRNP K controls cytosolic accumulation of TDP-43

Molecular neurodegeneration, 2013-09, Vol.8 (Suppl 1), p.P46-P46

2013

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Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. e67433

PloS one, 2013-06, Vol.8 (6)

2013

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Cotargeting BCL-2 and MCL-1 in high-risk B-ALL

Blood advances, 2020-06, Vol.4 (12), p.2762-2767

2020

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Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia

Blood, 2018-11, Vol.132 (Supplement 1), p.567-567

2018

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IDENTIFICATION OF POTENT BH3-MIMETIC COMBINATIONS TARGETING PRO-SURVIVAL PATHWAYS IN HUMAN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

Experimental hematology, 2019-08, Vol.76, p.S79-S80

2019

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TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-κB Dependent Induction of cFLIPL

PloS one, 2010-01, Vol.5 (1), p.e8620

2010

Volltextzugriff (PDF)

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Cell Death
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Proteins
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Cell Line, Tumor
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Phosphorylation
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Amyotrophic Lateral Sclerosis
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Amyotrophic Lateral Sclerosis - Genetics
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Dna-Binding Proteins - Metabolism
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Molecular mechanisms of cell death in neurological diseases

Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

CuII(atsm) Attenuates Neuroinflammation

The PKA paradox: Is Bim the answer?

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Metabolic Plasticity of Glioblastoma Cells in Response to DHODH Inhibitor BAY2402234 Treatment

Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

Effect of Structural Modifications to Glyoxal-bis(thiosemicarbazonato)copper(II) Complexes on Cellular Copper Uptake, Copper-Mediated ATP7A Trafficking, and P‑Glycoprotein Mediated Efflux

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

Proinflammatory microenvironment promotes lymphoma progression in mice with high megakaryocyte and TPO levels

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling

Cu II (atsm) Attenuates Neuroinflammation

Phosphorylation of hnRNP K controls cytosolic accumulation of TDP-43

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress. e67433

Cotargeting BCL-2 and MCL-1 in high-risk B-ALL

Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia

IDENTIFICATION OF POTENT BH3-MIMETIC COMBINATIONS TARGETING PRO-SURVIVAL PATHWAYS IN HUMAN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA

TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-κB Dependent Induction of cFLIPL

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