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Deciphering and Reversing Tumor Immune Suppression
Immunity (Cambridge, Mass.), 2013-07, Vol.39 (1), p.61-73
2013
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BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity
PloS one, 2022-05, Vol.17 (5), p.e0266980-e0266980
2022
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T-cell and NK-cell infiltration into solid tumors: a key limiting factor for efficacious cancer immunotherapy
Cancer discovery, 2014-05, Vol.4 (5), p.522-526
2014
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NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease
The Journal of immunology (1950), 2012-05, Vol.188 (9), p.4468-4475
2012
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NKG2D Mediates NK Cell Hyperresponsiveness and Influenza-Induced Pathologies in a Mouse Model of COPD
The Journal of immunology (1950), 2012-03, Vol.188 (9), p.4468-4475
2012
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Abstract 4985: Expression of FasL on the tumor endothelium establishes a selective immune barrier in ovarian cancer
Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.4985-4985
2013
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Abstract 2184: BOXR1030: A first-in-class CAR T-cell therapy co-expressing GOT2 enhances T-cell metabolic function for the treatment of GPC3-positive solid tumors
Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2184-2184
2020
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A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer
Journal of translational medicine, 2013-06, Vol.11 (1), p.149-149
2013
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Preliminary Clinical Results of a Phase 1 Study Evaluating the Safety and Anti-Tumor Activity of ACTR707 in Combination with Rituximab in Subjects with Relapsed or Refractory CD20+ B-Cell Lymphoma
Blood, 2018-11, Vol.132 (Supplement 1), p.2966-2966
2018
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Abstract 3762: Superior T cell activity of a membrane-proximal binding antibody when targeting Glypican-3 with an antibody-coupled T-cell receptor (ACTR) armed T cell
Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3762-3762
2017
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Adaptability of Antibody-Coupled T Cell Receptor (ACTR) Engineered Autologous T Cells in Combination with Daratumumab over CAR-Based Approaches
Blood, 2017-12, Vol.130, p.3189-3189
2017
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Abstract A163: Effective targeting of HER2-amplified cancers with trastuzumab in combination with T cells expressing a novel Antibody-Coupled T-cell Receptor (ACTR)
Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.A163-A163
2018
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Actr Platform As an Adaptable, Universal T Cell Therapy That Can Target Multiple Tumor Antigens to Overcome Antigen Escape
Blood, 2016-12, Vol.128 (22), p.3362-3362
2016
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Abstract B105: ACTR707: a novel T-cell therapy for the treatment of relapsed or refractory CD20+ B cell lymphoma in combination with rituximab
Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B105-B105
2018
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Abstract A003: Safety and preliminary efficacy of ACTR707, autologous T lymphocytes expressing an antibody-coupled T-cell receptor, in combination with rituximab in subjects with relapsed or refractory CD20-positive B-cell lymphoma
Cancer immunology research, 2019-02, Vol.7 (2_Supplement), p.A003-A003
2019
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