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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models

European journal of pharmacology, 2006-12, Vol.553 (1-3), p.109-119

2006

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Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist

British journal of pharmacology, 2000-08, Vol.130 (7), p.1606-1612

2000

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Characterization of [125I]‐SB‐258585 binding to human recombinant and native 5‐HT6 receptors in rat, pig and human brain tissue

British journal of pharmacology, 2000-08, Vol.130 (7), p.1597-1605

2000

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Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4867-4871

2005

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Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (18), p.4014-4018

2005

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Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists : Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (1), p.55-58

2001

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Novel C-2 Substituted Carbapenem Derivatives: Part IV. Synthesis and Biological Activity of Five Membered Heteroaromatic Derivatives

The Journal of Antibiotics, 1998/02/25, Vol.51(2), pp.210-220

1998

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5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046) : A potent, selective, and orally bioavailable 5-HT6 receptor antagonist

Journal of medicinal chemistry, 1999-01, Vol.42 (2), p.202-205

1999

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5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT6 Receptor Antagonist

Journal of medicinal chemistry, 1999-01, Vol.42 (2), p.202-205

1999

Volltextzugriff (PDF)

Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT 6 receptor antagonists

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4867-4871

2005

Volltextzugriff (PDF)

Characterization of [ 125 I]‐SB‐258585 binding to human recombinant and native 5‐HT 6 receptors in rat, pig and human brain tissue

British journal of pharmacology, 2009-01, Vol.130 (7), p.1597-1605

2009

Volltextzugriff (PDF)

Characterization of SB‐271046: A potent, selective and orally active 5‐HT 6 receptor antagonist

British journal of pharmacology, 2009-01, Vol.130 (7), p.1606-1612

2009

Volltextzugriff (PDF)

Novel C-2 Substituted Carbapenem Derivatives: Part II. Synthesis and Structure-activity Relationships of Isoxazolin-2-yl, Isoxazolidin-2-yl and 2-Pyrazolin-2-yl Carbapenems Generated Using 1, 3-Dipolar Cycloaddition Chemistry

The Journal of Antibiotics, 1996/12/25, Vol.49(12), pp.1266-1274

1996

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Novel C-2 Substituted Carbapenem Derivatives: Part III. Synthesis and Biological Activity of 2-(Functionalised Ethenyl, Oxyiminomethyl and α-[Hydroxy]benzyl)-Carbapenems

The Journal of Antibiotics, 1997/03/25, Vol.50(3), pp.237-245

1997

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Novel C-2 Substituted Carbapenem Derivatives Part III. Synthesis and Biological Activity of 2-(Functionalised Ethenyl, Oxyiminomethyl and .ALPHA.-(Hydroxy)benzyl)-Carbapenems

Journal of antibiotics, 1997, Vol.50 (3), p.237-245

1997

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Discovery of a potent and selective 5-ht 5A receptor antagonist by high-throughput chemistry

Bioorganic & medicinal chemistry letters, 2005, Vol.15 (18), p.4014-4018

2005

Volltextzugriff (PDF)

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT(6) receptor

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (21), p.2843-2846

2001

Volltextzugriff (PDF)

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (21), p.2843-2846

2001

Volltextzugriff (PDF)

SB-399885 is a potent, selective 5-HT 6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models

European journal of pharmacology, 2006, Vol.553 (1), p.109-119

2006

Volltextzugriff (PDF)

WITHDRAWN: Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists

Bioorganic & medicinal chemistry, 2005-07

2005

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An Expedient Synthesis of Allylic Polyprenyl Phosphates

Synthetic communications, 1999-08, Vol.29 (15), p.2639-2644

1999

Volltextzugriff (PDF)

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT 6 receptor

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (21), p.2843-2846

2001

Volltextzugriff (PDF)

Phenyl benzenesulfonamides are novel and selective 5-HT 6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

Bioorganic & medicinal chemistry letters, 2001, Vol.11 (1), p.55-58

2001

Volltextzugriff (PDF)

5-Chloro- N -(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT 6 Receptor Antagonist

Journal of medicinal chemistry, 1999-01, Vol.42 (2), p.202-205

1999

Volltextzugriff (PDF)

Synthesis of annelated 1,3,4,6-thiatriazepines from dichlorodiazabutadienes and cyclic thioureas

Journal of the Chemical Society. Chemical communications, 1980 (4), p.156

1980

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SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models

Characterization of SB‐271046: A potent, selective and orally active 5‐HT6 receptor antagonist

Characterization of [125I]‐SB‐258585 binding to human recombinant and native 5‐HT6 receptors in rat, pig and human brain tissue

Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists

Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry

Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists : Identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

Novel C-2 Substituted Carbapenem Derivatives: Part IV. Synthesis and Biological Activity of Five Membered Heteroaromatic Derivatives

5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046) : A potent, selective, and orally bioavailable 5-HT6 receptor antagonist

5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT6 Receptor Antagonist

Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT 6 receptor antagonists

Characterization of [ 125 I]‐SB‐258585 binding to human recombinant and native 5‐HT 6 receptors in rat, pig and human brain tissue

Characterization of SB‐271046: A potent, selective and orally active 5‐HT 6 receptor antagonist

Novel C-2 Substituted Carbapenem Derivatives: Part II. Synthesis and Structure-activity Relationships of Isoxazolin-2-yl, Isoxazolidin-2-yl and 2-Pyrazolin-2-yl Carbapenems Generated Using 1, 3-Dipolar Cycloaddition Chemistry

Novel C-2 Substituted Carbapenem Derivatives: Part III. Synthesis and Biological Activity of 2-(Functionalised Ethenyl, Oxyiminomethyl and α-[Hydroxy]benzyl)-Carbapenems

Novel C-2 Substituted Carbapenem Derivatives Part III. Synthesis and Biological Activity of 2-(Functionalised Ethenyl, Oxyiminomethyl and .ALPHA.-(Hydroxy)benzyl)-Carbapenems

Discovery of a potent and selective 5-ht 5A receptor antagonist by high-throughput chemistry

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT(6) receptor

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT6 receptor

SB-399885 is a potent, selective 5-HT 6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models

WITHDRAWN: Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists

An Expedient Synthesis of Allylic Polyprenyl Phosphates

Novel (4-piperazin-1-ylquinolin-6-yl) arylsulfonamides with high affinity and selectivity for the 5-HT 6 receptor

Phenyl benzenesulfonamides are novel and selective 5-HT 6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134)

5-Chloro- N -(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT 6 Receptor Antagonist

Synthesis of annelated 1,3,4,6-thiatriazepines from dichlorodiazabutadienes and cyclic thioureas

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