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Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation

Developmental cell, 2012-08, Vol.23 (2), p.280-291

2012

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De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects

PLoS genetics, 2016-04, Vol.12 (4), p.e1005963-e1005963

2016

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Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development

PLoS genetics, 2019-05, Vol.15 (5), p.e1007711-e1007711

2019

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Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription

Nature structural & molecular biology, 2017-07, Vol.24 (7), p.596

2017

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Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease

Human molecular genetics, 2012-07, Vol.21 (14), p.3255-3263

2012

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The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation

Developmental cell, 2016-02, Vol.36 (3), p.262-275

2016

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Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (8), p.E1422-E1431

2017

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A promoter interaction map for cardiovascular disease genetics

eLife, 2018-07, Vol.7

2018

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A common genetic variant within SCN10A modulates cardiac SCN5A expression

The Journal of clinical investigation, 2014-04, Vol.124 (4), p.1844-1852

2014

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A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human

Nature communications, 2018-10, Vol.9 (1), p.4237-18, Article 4237

2018

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Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation

Nature communications, 2023-08, Vol.14 (1), p.4999-4999, Article 4999

2023

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Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

Cell reports (Cambridge), 2024-06, Vol.43 (6), p.114284-114284, Article 114284

2024

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Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation

PLoS genetics, 2014-10, Vol.10 (10), p.e1004604-e1004604

2014

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Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (52), p.19836-19841

2006

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Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects

PloS one, 2011-06, Vol.6 (6), p.e20803-e20803

2011

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Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq

PLoS computational biology, 2020-02, Vol.16 (2), p.e1007119-e1007119

2020

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sonic hedgehog is required in pulmonary endoderm for atrial septation

Development (Cambridge), 2009-05, Vol.136 (10), p.1761-1770

2009

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Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

eLife, 2021-10, Vol.10

2021

Volltextzugriff (PDF)

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction

Journal of molecular and cellular cardiology, 2012-03, Vol.52 (3), p.638-649

2012

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ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

Cell reports (Cambridge), 2023-06, Vol.42 (6), p.112665-112665, Article 112665

2023

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A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice

eLife, 2019-03, Vol.8

2019

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The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system

Development (Cambridge), 2004-08, Vol.131 (16), p.4107-4116

2004

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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

Developmental cell, 2020-03, Vol.52 (6), p.699-713.e11

2020

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Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.E2020-E2029

2015

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Tbx5-Hedgehog Molecular Networks Are Essential in the Second Heart Field for Atrial Septation

De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects

Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development

Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription

Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease

The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation

Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation

A promoter interaction map for cardiovascular disease genetics

A common genetic variant within SCN10A modulates cardiac SCN5A expression

A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human

Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation

Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice

Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation

Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis

Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects

Chromatin-enriched RNAs mark active and repressive cis-regulation: An analysis of nuclear RNA-seq

sonic hedgehog is required in pulmonary endoderm for atrial septation

Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development

Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction

ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice

The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system

Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm

Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development

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