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Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect

Neuroscience and biobehavioral reviews, 2011-10, Vol.35 (9), p.1831-1836

2011

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GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

Neuropsychopharmacology (New York, N.Y.), 2013-04, Vol.38 (5), p.729-742

2013

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Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent

Journal of psychiatric practice, 2015-03, Vol.21 (2), p.140-149

2015

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GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

Expert opinion on investigational drugs, 2014-02, Vol.23 (2), p.243-254

2014

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Neurobiology of 50-kHz ultrasonic vocalizations in rats: Electrode mapping, lesion, and pharmacology studies

Behavioural brain research, 2007-09, Vol.182 (2), p.274-283

2007

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Ultrasonic Vocalizations of Rats (Rattus norvegicus) During Mating, Play, and Aggression: Behavioral Concomitants, Relationship to Reward, and Self-Administration of Playback

Journal of comparative psychology (1983), 2008-11, Vol.122 (4), p.357-367

2008

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A prefrontal cortex alpha/delta switch controls the transition from positive to negative affective states

Discover Mental Health, 2023-10, Vol.3 (1), p.19-19, Article 19

2023

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The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant

Current neuropharmacology, 2017-01, Vol.15 (1), p.47-56

2017

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Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like Effects

The international journal of neuropsychopharmacology, 2019-03, Vol.22 (3), p.247-259

2019

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NMDAR activation regulates the daily rhythms of sleep and mood

Sleep (New York, N.Y.), 2019-10, Vol.42 (10), p.1

2019

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A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism

Neuroscience and biobehavioral reviews, 2011-10, Vol.35 (9), p.1982-1988

2011

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Effect of a Novel NMDA Receptor Modulator, Rapastinel (Formerly GLYX-13), in OCD: Proof of Concept

The American journal of psychiatry, 2016-12, Vol.173 (12), p.1239-1241

2016

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Social, communication, and cortical structural impairments in Epac2-deficient mice

The Journal of neuroscience, 2012-08, Vol.32 (34), p.11864-11878

2012

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Insulin-Like Growth Factor I Produces an Antidepressant-Like Effect and Elicits N-Methyl-D-Aspartate Receptor Independent Long-Term Potentiation of Synaptic Transmission in Medial Prefrontal Cortex and Hippocampus

The international journal of neuropsychopharmacology, 2015-09, Vol.19 (2), p.pyv101

2015

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The concept of “aldehyde load” in neurodegenerative mechanisms: Cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line

Brain research, 2007-05, Vol.1145, p.150-156

2007

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Overexpression of ST6GalNAcV, a ganglioside-specific α2,6-sialyltransferase, inhibits glioma growth in vivo

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (28), p.12646-12651

2010

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Integrated Transcriptomic and Glycomic Profiling of Glioma Stem Cell Xenografts

Journal of proteome research, 2015-09, Vol.14 (9), p.3932-3939

2015

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Focused microarray analysis of glyco-gene expression in human glioblastomas

Journal of neurochemistry, 2007-11, Vol.103 (s1), p.14-24

2007

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An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome

Molecular psychiatry, 2023-03, Vol.28 (3), p.1101-1111

2023

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The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats

Developmental psychobiology, 2009-01, Vol.51 (1), p.34-46

2009

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From emotional arousal to executive action. Role of the prefrontal cortex

Brain structure & function, 2024-08

2024

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GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice

Behavioural brain research, 2016-02, Vol.299, p.105-110

2016

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Zelquistinel acts at an extracellular binding domain to modulate intracellular calcium inactivation of N-methyl-d-aspartate receptors

Neuropharmacology, 2024-11, Vol.259, p.110100, Article 110100

2024

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Rough-and-tumble play induces resilience to stress in rats

Neuroreport, 2017-12, Vol.28 (17), p.1122-1126

2017

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Glycomic and Transcriptomic Response of GSC11 Glioblastoma Stem Cells to STAT3 Phosphorylation Inhibition and Serum-Induced Differentiation

Journal of proteome research, 2010-05, Vol.9 (5), p.2098-2108

2010

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Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect

GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects

Randomized proof of concept trial of GLYX-13, an N-methyl-D-aspartate receptor glycine site partial agonist, in major depressive disorder nonresponsive to a previous antidepressant agent

GLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonists

Neurobiology of 50-kHz ultrasonic vocalizations in rats: Electrode mapping, lesion, and pharmacology studies

Ultrasonic Vocalizations of Rats (Rattus norvegicus) During Mating, Play, and Aggression: Behavioral Concomitants, Relationship to Reward, and Self-Administration of Playback

A prefrontal cortex alpha/delta switch controls the transition from positive to negative affective states

The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant

Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like Effects

NMDAR activation regulates the daily rhythms of sleep and mood

A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism

Effect of a Novel NMDA Receptor Modulator, Rapastinel (Formerly GLYX-13), in OCD: Proof of Concept

Social, communication, and cortical structural impairments in Epac2-deficient mice

Insulin-Like Growth Factor I Produces an Antidepressant-Like Effect and Elicits N-Methyl-D-Aspartate Receptor Independent Long-Term Potentiation of Synaptic Transmission in Medial Prefrontal Cortex and Hippocampus

The concept of “aldehyde load” in neurodegenerative mechanisms: Cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell line

Overexpression of ST6GalNAcV, a ganglioside-specific α2,6-sialyltransferase, inhibits glioma growth in vivo

Integrated Transcriptomic and Glycomic Profiling of Glioma Stem Cell Xenografts

Focused microarray analysis of glyco-gene expression in human glioblastomas

An IGFBP2-derived peptide promotes neuroplasticity and rescues deficits in a mouse model of Phelan-McDermid syndrome

The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats

From emotional arousal to executive action. Role of the prefrontal cortex

GLYX-13 (rapastinel) ameliorates subchronic phencyclidine- and ketamine-induced declarative memory deficits in mice

Zelquistinel acts at an extracellular binding domain to modulate intracellular calcium inactivation of N-methyl-d-aspartate receptors

Rough-and-tumble play induces resilience to stress in rats

Glycomic and Transcriptomic Response of GSC11 Glioblastoma Stem Cells to STAT3 Phosphorylation Inhibition and Serum-Induced Differentiation

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