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Drug‐induced liver injury: Advances in mechanistic understanding that will inform risk management

Clinical pharmacology and therapeutics, 2017-04, Vol.101 (4), p.469-480

2017

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Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials

Clinical pharmacology and therapeutics, 2017-12, Vol.102 (6), p.961-969

2017

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Climate Change and Crop Exposure to Adverse Weather: Changes to Frost Risk and Grapevine Flowering Conditions

PloS one, 2015-10, Vol.10 (10), p.e0141218-e0141218

2015

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Climate change impacts and adaptive strategies: lessons from the grapevine

Global change biology, 2016-11, Vol.22 (11), p.3814-3828

2016

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Large eddy simulation using high-resolution and high-order methods

Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2009-07, Vol.367 (1899), p.2985-2997

2009

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Proteostasis is adaptive: Balancing chaperone holdases against foldases

PLoS computational biology, 2020-12, Vol.16 (12), p.e1008460-e1008460

2020

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The effectiveness of UK protected areas in preventing local extinctions

Conservation letters, 2023-11, Vol.16 (6), p.n/a

2023

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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis

PloS one, 2019-01, Vol.14 (1), p.e0208958-e0208958

2019

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Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Cell metabolism, 2008-01, Vol.7 (1), p.45-56

2008

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Granger Causality of Coupled Climate Processes: Ocean Feedback on the North Atlantic Oscillation

Journal of climate, 2006-04, Vol.19 (7), p.1182-1194

2006

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Moral Encounters in Tourism

1, 2014

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Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

Toxicological sciences, 2017-01, Vol.155 (1), p.61-74

2017

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Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

Food and chemical toxicology, 2015-02, Vol.76, p.19-26

2015

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What is the impact of flexicurity on the chances of entry into employment for people with low education and activity limitations due to health problems? A comparison of 21 European countries using Qualitative Comparative Analysis (QCA)

BMC public health, 2016-08, Vol.16 (1), p.842-842, Article 842

2016

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PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Journal of lipid research, 2013-02, Vol.54 (2), p.522-534

2013

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The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

Nature structural & molecular biology, 2005-09, Vol.12 (9), p.763-771

2005

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Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

The EMBO journal, 2011-02, Vol.30 (4), p.692-705

2011

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The Fanconi Anaemia Gene FANCC Promotes Homologous Recombination and Error-Prone DNA Repair

Molecular cell, 2004-08, Vol.15 (4), p.607-620

2004

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Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury

Toxicological sciences, 2019-02, Vol.167 (2), p.458-467

2019

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Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression

Journal of pharmaceutical sciences, 2021-01, Vol.110 (1), p.412-421

2021

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Mechanistic microclimate models and plant pest risk modelling

Journal of pest science, 2024-05

2024

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Bioprinted liver provides early insight into the role of Kupffer cells in TGF-[beta]1 and methotrexate-induced fibrogenesis

PloS one, 2019-01, Vol.14 (1), p.e0208958

2019

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Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa)

Toxicological sciences, 2018-02, Vol.161 (2), p.401-411

2018

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FANCE: the link between Fanconi anaemia complex assembly and activity

The EMBO journal, 2002-07, Vol.21 (13), p.3414-3423

2002

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Circulating levels of MCP-1 and eotaxin are not associated with presence of atherosclerosis or previous myocardial infarction

Atherosclerosis, 2005-12, Vol.183 (2), p.268-274

2005

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Drug‐induced liver injury: Advances in mechanistic understanding that will inform risk management

Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials

Climate Change and Crop Exposure to Adverse Weather: Changes to Frost Risk and Grapevine Flowering Conditions

Climate change impacts and adaptive strategies: lessons from the grapevine

Large eddy simulation using high-resolution and high-order methods

Proteostasis is adaptive: Balancing chaperone holdases against foldases

The effectiveness of UK protected areas in preventing local extinctions

Bioprinted liver provides early insight into the role of Kupffer cells in TGF-β1 and methotrexate-induced fibrogenesis

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Granger Causality of Coupled Climate Processes: Ocean Feedback on the North Atlantic Oscillation

Moral Encounters in Tourism

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

What is the impact of flexicurity on the chances of entry into employment for people with low education and activity limitations due to health problems? A comparison of 21 European countries using Qualitative Comparative Analysis (QCA)

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

The Fanconi Anaemia Gene FANCC Promotes Homologous Recombination and Error-Prone DNA Repair

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury

Pregnancy-Related Hormones Increase Nifedipine Metabolism in Human Hepatocytes by Inducing CYP3A4 Expression

Mechanistic microclimate models and plant pest risk modelling

Bioprinted liver provides early insight into the role of Kupffer cells in TGF-[beta]1 and methotrexate-induced fibrogenesis

Transient Changes in Hepatic Physiology That Alter Bilirubin and Bile Acid Transport May Explain Elevations in Liver Chemistries Observed in Clinical Trials of GGF2 (Cimaglermin Alfa)

FANCE: the link between Fanconi anaemia complex assembly and activity

Circulating levels of MCP-1 and eotaxin are not associated with presence of atherosclerosis or previous myocardial infarction

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