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p62 in Cancer: Signaling Adaptor Beyond Autophagy

Cell, 2016-10, Vol.167 (3), p.606-609

2016

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Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis

Cancer cell, 2014-07, Vol.26 (1), p.121-135

2014

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p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

Cell, 2009-06, Vol.137 (6), p.1001-1004

2009

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The Dual Roles of the Atypical Protein Kinase Cs in Cancer

Cancer cell, 2019-09, Vol.36 (3), p.218-235

2019

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p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

Cancer cell, 2016-06, Vol.29 (6), p.935-948

2016

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p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer

Cancer cell, 2016-10, Vol.30 (4), p.595-609

2016

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p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

Molecular cell, 2011-10, Vol.44 (1), p.134-146

2011

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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

Nature communications, 2021-05, Vol.12 (1), p.2876-13, Article 2876

2021

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NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly

Journal of hepatology, 2020-06, Vol.72 (6), p.1182-1195

2020

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K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells

Molecular cell, 2013-08, Vol.51 (3), p.283-296

2013

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Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

Developmental cell, 2021-01, Vol.56 (1), p.95-110.e10

2021

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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas

Cancer cell, 2017-12, Vol.32 (6), p.824-839.e8

2017

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ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma

Cell metabolism, 2017-12, Vol.26 (6), p.817-829.e6

2017

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ZZ-dependent regulation of p62/SQSTM1 in autophagy

Nature communications, 2018-10, Vol.9 (1), p.4373-11, Article 4373

2018

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Fructose stimulated de novo lipogenesis is promoted by inflammation

Nature metabolism, 2020-10, Vol.2 (10), p.1034-1045

2020

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miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3

Cancer research (Chicago, Ill.), 2016-10, Vol.76 (19), p.5777-5787

2016

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Metabolic reprogramming of the tumor microenvironment by p62 and its partners

Biochimica et biophysica acta. Reviews on cancer, 2018-08, Vol.1870 (1), p.88-95

2018

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Immunosurveillance, interferon, and autophagic networking in cancer: the PRKCI-ULK2 paradigm

Autophagy, 2022-01, Vol.18 (1), p.226-227

2022

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p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors

Cancer cell, 2019-01, Vol.35 (1), p.46-63.e10

2019

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Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade

Cell reports (Cambridge), 2015-08, Vol.12 (8), p.1339-1352

2015

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SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity

PloS one, 2013-09, Vol.8 (9), p.e76016-e76016

2013

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Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

Immunity (Cambridge, Mass.), 2018-12, Vol.49 (6), p.1132-1147.e7

2018

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The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer

Cell reports (Cambridge), 2018-04, Vol.23 (4), p.1178-1191

2018

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Cell Signaling and Function Organized by PB1 Domain Interactions

Molecular cell, 2006-09, Vol.23 (5), p.631-640

2006

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p62 in Cancer: Signaling Adaptor Beyond Autophagy

Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

The Dual Roles of the Atypical Protein Kinase Cs in Cancer

p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells

p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ

NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly

K63 Polyubiquitination and Activation of mTOR by the p62-TRAF6 Complex in Nutrient-Activated Cells

Stromal SOX2 Upregulation Promotes Tumorigenesis through the Generation of a SFRP1/2-Expressing Cancer-Associated Fibroblast Population

Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas

ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma

The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation

ZZ-dependent regulation of p62/SQSTM1 in autophagy

Fructose stimulated de novo lipogenesis is promoted by inflammation

miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3

Metabolic reprogramming of the tumor microenvironment by p62 and its partners

Immunosurveillance, interferon, and autophagic networking in cancer: the PRKCI-ULK2 paradigm

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors

Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity

Simultaneous Loss of Both Atypical Protein Kinase C Genes in the Intestinal Epithelium Drives Serrated Intestinal Cancer by Impairing Immunosurveillance

The Secretion of miR-200s by a PKCζ/ADAR2 Signaling Axis Promotes Liver Metastasis in Colorectal Cancer

Cell Signaling and Function Organized by PB1 Domain Interactions

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