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Role of monocarboxylate transporters in drug delivery to the brain

Current pharmaceutical design, 2014-03, Vol.20 (10), p.1487

2014

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Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease

Pharmacological reviews, 2020-04, Vol.72 (2), p.466-485

2020

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SLC and ABC Transporters: Expression, Localization, and Species Differences at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers

The AAPS journal, 2017-09, Vol.19 (5), p.1317-1331

2017

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Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration

The AAPS journal, 2012-09, Vol.14 (3), p.559-570

2012

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Novel high/low solubility classification methods for new molecular entities

International journal of pharmaceutics, 2016-09, Vol.511 (1), p.111-126

2016

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MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

Molecular pharmacology, 2009-06, Vol.75 (6), p.1374-1379

2009

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Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators

Drug metabolism and disposition, 2005-11, Vol.33 (11), p.1666

2005

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Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism

Toxicology in vitro, 2006-03, Vol.20 (2), p.187-210

2006

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Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport

Drug metabolism and disposition, 2014-09, Vol.42 (9), p.1357

2014

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The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin efflux

Drug metabolism and disposition, 2011-03, Vol.39 (3), p.426

2011

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Development and validation of a liquid chromatography tandem mass spectrometry assay for AZD3965 in mouse plasma and tumor tissue: Application to pharmacokinetic and breast tumor xenograft studies

Journal of pharmaceutical and biomedical analysis, 2018-06, Vol.155, p.270-275

2018

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Increased megalin expression in early type 2 diabetes: role of insulin-signaling pathways

American journal of physiology. Renal physiology, 2018-11, Vol.315 (5), p.F1191-F1207

2018

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Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

The Journal of pharmacology and experimental therapeutics, 2003-03, Vol.304 (3), p.1258

2003

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Flavonoids Are Inhibitors of Breast Cancer Resistance Protein (ABCG2)-Mediated Transport

Molecular pharmacology, 2004-05, Vol.65 (5), p.1208-1216

2004

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Quercetin pharmacokinetics in humans

Biopharmaceutics & drug disposition, 2008-05, Vol.29 (4), p.205-217

2008

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Commentary on global graduate programs in the pharmaceutical sciences

Journal of pharmaceutical sciences, 2022-12, Vol.111 (12), p.3195-3195

Morris, Marilyn E

2022

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Toxicokinetic/Toxicodynamic Interaction Studies in Rats between the Drugs of Abuse γ-Hydroxybutyric Acid and Ketamine and Treatment Strategies for Overdose

Pharmaceutics, 2021-05, Vol.13 (5), p.741

2021

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Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2

Drug metabolism and disposition, 2007-02, Vol.35 (2), p.268

2007

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Pharmacokinetics and Pharmacodynamics of Phenethyl Isothiocyanate: Implications in Breast Cancer Prevention

The AAPS journal, 2014-07, Vol.16 (4), p.705-713

2014

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Targeting the Choroid Plexuses for Protein Drug Delivery

Pharmaceutics, 2020-10, Vol.12 (10), p.963

2020

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Monocarboxylate Transporter 6-Mediated Interactions with Prostaglandin F2α: In Vitro and In Vivo Evidence Utilizing a Knockout Mouse Model

Pharmaceutics, 2020-02, Vol.12 (3), p.201

2020

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Untargeted metabolomics identifies the potential role of monocarboxylate transporter 6 (MCT6/SLC16A5) in lipid and amino acid metabolism pathways

Pharmacology research & perspectives, 2022-06, Vol.10 (3), p.e00944-n/a

2022

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HPLC analysis of mitoxantrone in mouse plasma and tissues: Application in a pharmacokinetic study

Journal of pharmaceutical and biomedical analysis, 2010-02, Vol.51 (3), p.750-753

2010

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An Extended Minimal Physiologically Based Pharmacokinetic Model: Evaluation of Type II Diabetes Mellitus and Diabetic Nephropathy on Human IgG Pharmacokinetics in Rats

The AAPS journal, 2015-11, Vol.17 (6), p.1464-1474

2015

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Simulation-Based Analysis of the Impact of Renal Impairment on the Pharmacokinetics of Highly Metabolized Compounds

Pharmaceutics, 2019-03, Vol.11 (3), p.105

2019

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Role of monocarboxylate transporters in drug delivery to the brain

Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease

SLC and ABC Transporters: Expression, Localization, and Species Differences at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers

Mechanistic Determinants of Biotherapeutics Absorption Following SC Administration

Novel high/low solubility classification methods for new molecular entities

MicroRNA-328 Negatively Regulates the Expression of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Cancer Cells

Flavonoids as a novel class of human organic anion-transporting polypeptide OATP1B1 (OATP-C) modulators

Dietary flavonoids: Effects on xenobiotic and carcinogen metabolism

Flavonoids are inhibitors of human organic anion transporter 1 (OAT1)-mediated transport

The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin efflux

Development and validation of a liquid chromatography tandem mass spectrometry assay for AZD3965 in mouse plasma and tumor tissue: Application to pharmacokinetic and breast tumor xenograft studies

Increased megalin expression in early type 2 diabetes: role of insulin-signaling pathways

Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

Flavonoids Are Inhibitors of Breast Cancer Resistance Protein (ABCG2)-Mediated Transport

Quercetin pharmacokinetics in humans

Commentary on global graduate programs in the pharmaceutical sciences

Toxicokinetic/Toxicodynamic Interaction Studies in Rats between the Drugs of Abuse γ-Hydroxybutyric Acid and Ketamine and Treatment Strategies for Overdose

Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2

Pharmacokinetics and Pharmacodynamics of Phenethyl Isothiocyanate: Implications in Breast Cancer Prevention

Targeting the Choroid Plexuses for Protein Drug Delivery

Monocarboxylate Transporter 6-Mediated Interactions with Prostaglandin F2α: In Vitro and In Vivo Evidence Utilizing a Knockout Mouse Model

Untargeted metabolomics identifies the potential role of monocarboxylate transporter 6 (MCT6/SLC16A5) in lipid and amino acid metabolism pathways

HPLC analysis of mitoxantrone in mouse plasma and tissues: Application in a pharmacokinetic study

An Extended Minimal Physiologically Based Pharmacokinetic Model: Evaluation of Type II Diabetes Mellitus and Diabetic Nephropathy on Human IgG Pharmacokinetics in Rats

Simulation-Based Analysis of the Impact of Renal Impairment on the Pharmacokinetics of Highly Metabolized Compounds

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