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Identification of Novel Ligands for the Gabapentin Binding Site on the α2δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1838-1845

1998

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A hydrogen-bonded, double-helical macrocycle

Journal of the American Chemical Society, 1993-01, Vol.115 (2), p.813-814

1993

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The generation and reactivity of oxygen centered radicals from the photolysis of derivatives of N-hydroxy-2-thiopyridone

Tetrahedron letters, 1991-01, Vol.32 (3), p.311-314

1991

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Solid-phase compound library synthesis in drug design and development

Current opinion in drug discovery & development, 2002-07, Vol.5 (4), p.594

2002

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Chapter 3 - High Throughput Reaction Screening

New Synthetic Technologies in Medicinal Chemistry, 2012, p.42-62

Morrell, Andrew I.

2012

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Investigation into the preferred conformation of gabapentin for interaction with its binding site on the α2δ subunit of a calcium channel

Bioorganic & medicinal chemistry letters, 1997-10, Vol.7 (19), p.2481-2484

1997

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The design and synthesis of non-peptide ligands with affinity and selectivity for tachykinin receptors

Bioorganic & medicinal chemistry letters, 1996-01, Vol.6 (2), p.165-166

1996

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Cyclobutylcarbinyl radical cleavage in the bicyclo[3.2.0]heptanone ring system

Tetrahedron letters, 1995-01, Vol.36 (3), p.459-460

1995

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Identification of Novel Ligands for the Gabapentin Binding Site on the α 2 δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1838-1845

1998

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Formation of the oxatricyclo[3.2.1.0 3,6]octane ring system via an intramolecular bromoetherification

Tetrahedron letters, 1994-04, Vol.35 (14), p.2221-2222

1994

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Solid-Phase Compound Library Synthesis in Drug Design and Development

ChemInform, 2003-09, Vol.34 (35), p.no-no

2003

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Responsive cortical stimulation for the treatment of medically intractable partial epilepsy

Neurology, 2011-09, Vol.77 (13), p.1295-1304

Morrell, Martha J

2011

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Haplotype-resolved powdery mildew resistance loci reveal the impact of heterozygous structural variation on NLR genes in Muscadinia rotundifolia

G3 : genes - genomes - genetics, 2022-07, Vol.12 (8)

2022

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MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension

Circulation research, 2015-10, Vol.117 (10), p.870-883

2015

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Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2017-01, Vol.135 (5), p.460-475

2017

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Long-term safety and efficacy of imatinib in pulmonary arterial hypertension

The Journal of heart and lung transplantation, 2015-11, Vol.34 (11), p.1366-1375

2015

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HIF2α–arginase axis is essential for the development of pulmonary hypertension

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (31), p.8801-8806

2016

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Myocardin regulates vascular smooth muscle cell inflammatory activation and disease

Arteriosclerosis, thrombosis, and vascular biology, 2015-04, Vol.35 (4), p.817-828

2015

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Microfluidic encapsulation of photosynthetic cyanobacteria in hydrogel microparticles augments oxygen delivery to rescue ischemic myocardium

Journal of bioscience and bioengineering, 2023-06, Vol.135 (6), p.493-499

2023

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Caveolae protect endothelial cells from membrane rupture during increased cardiac output

The Journal of cell biology, 2015-10, Vol.211 (1), p.53-61

2015

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Barley whole exome capture: a tool for genomic research in the genus Hordeum and beyond

The Plant journal : for cell and molecular biology, 2013-11, Vol.76 (3), p.494-505

2013

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Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

Arteriosclerosis, thrombosis, and vascular biology, 2010-04, Vol.30 (4), p.716-723

2010

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Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial

Epilepsia (Copenhagen), 2014-03, Vol.55 (3), p.432-441

2014

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Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial

The lancet respiratory medicine, 2014-10, Vol.2 (10), p.804-812

2014

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Identification of Novel Ligands for the Gabapentin Binding Site on the α2δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

A hydrogen-bonded, double-helical macrocycle

The generation and reactivity of oxygen centered radicals from the photolysis of derivatives of N-hydroxy-2-thiopyridone

Solid-phase compound library synthesis in drug design and development

Chapter 3 - High Throughput Reaction Screening

Investigation into the preferred conformation of gabapentin for interaction with its binding site on the α2δ subunit of a calcium channel

The design and synthesis of non-peptide ligands with affinity and selectivity for tachykinin receptors

Cyclobutylcarbinyl radical cleavage in the bicyclo[3.2.0]heptanone ring system

Identification of Novel Ligands for the Gabapentin Binding Site on the α 2 δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

Formation of the oxatricyclo[3.2.1.0 3,6]octane ring system via an intramolecular bromoetherification

Solid-Phase Compound Library Synthesis in Drug Design and Development

Responsive cortical stimulation for the treatment of medically intractable partial epilepsy

Haplotype-resolved powdery mildew resistance loci reveal the impact of heterozygous structural variation on NLR genes in Muscadinia rotundifolia

MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension

Luminous Type II Short-Plateau Supernovae 2006Y, 2006ai, and 2016egz: A Transitional Class from Stripped Massive Red Supergiants

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension

Long-term safety and efficacy of imatinib in pulmonary arterial hypertension

HIF2α–arginase axis is essential for the development of pulmonary hypertension

Myocardin regulates vascular smooth muscle cell inflammatory activation and disease

Microfluidic encapsulation of photosynthetic cyanobacteria in hydrogel microparticles augments oxygen delivery to rescue ischemic myocardium

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

Barley whole exome capture: a tool for genomic research in the genus Hordeum and beyond

Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial

Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial

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