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Insights from a high-fat diet fed mouse model with a humanized liver

PloS one, 2022-05, Vol.17 (5), p.e0268260-e0268260

2022

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Impact of silencing hepatic SREBP-1 on insulin signaling

PloS one, 2018-05, Vol.13 (5), p.e0196704-e0196704

2018

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Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

The Journal of biological chemistry, 2014-02, Vol.289 (9), p.5510-5517

2014

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Role of non-coding RNAs on liver metabolism and NAFLD pathogenesis

Human molecular genetics, 2022-10, Vol.31 (R1), p.R4-R21

2022

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Aberrant gene expression induced by a high fat diet is linked to H3K9 acetylation in the promoter-proximal region

Biochimica et biophysica acta. Gene regulatory mechanisms, 2021-03, Vol.1864 (3), p.194691-194691, Article 194691

2021

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Sex- and age-associated factors drive the pathophysiology of MASLD

Hepatology communications, 2024-09, Vol.8 (9)

2024

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Novel targets and therapeutic strategies for type 2 diabetes

Trends in endocrinology and metabolism, 2003-05, Vol.14 (4), p.169-175

Morral, Núria

2003

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Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12816-12821

1999

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Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver

Journal of lipid research, 2007-07, Vol.48 (7), p.1499-1510

2007

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Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies

BMC research notes, 2011-01, Vol.4 (1), p.8-8, Article 8

2011

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Gene targets of mouse miR-709: regulation of distinct pools

Scientific reports, 2016-01, Vol.6 (1), p.18958-18958, Article 18958

2016

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Enhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice

American journal of physiology. Regulatory, integrative and comparative physiology, 2015-01, Vol.308 (2), p.R131-R137

2015

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Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers

Journal of lipid research, 2007-07, Vol.48 (7), p.1499-1510

2007

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Insights from a high-fat diet fed mouse model with a humanized liver

PloS one, 2022-01, Vol.17 (5)

2022

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Helper-dependent Adenovirus-mediated Short Hairpin RNA Expression in the Liver Activates the Interferon Response

The Journal of biological chemistry, 2008-01, Vol.283 (4), p.2120-2128

2008

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Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes

Human gene therapy, 2002-09, Vol.13 (13), p.1561-1570

2002

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Hepatic insulin expression improves glycemic control in type 1 diabetic rats

Diabetes research and clinical practice, 2001-06, Vol.52 (3), p.153-163

2001

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Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors

Human gene therapy, 2009-01, Vol.20 (1), p.87-94

2009

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Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors

Human gene therapy. Part B. Methods, 2013-02, Vol.24 (1), p.1-10

2013

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Gene therapy for inherited retinal and optic nerve degenerations

Expert opinion on biological therapy, 2018-01, Vol.18 (1), p.37-49

2018

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Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules

Human gene therapy, 2011-12, Vol.22 (12), p.1483-1497

2011

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Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

Nature genetics, 1998-02, Vol.18 (2), p.180-183

1998

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Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

The Journal of biological chemistry, 2017-06, Vol.292 (25), p.10455-10464

2017

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Gene therapy for age-related macular degeneration

Expert opinion on biological therapy, 2017-10, Vol.17 (10), p.1235-1244

2017

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Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

Human gene therapy, 2002-01, Vol.13 (1), p.143-154

2002

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Insights from a high-fat diet fed mouse model with a humanized liver

Impact of silencing hepatic SREBP-1 on insulin signaling

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver

Role of non-coding RNAs on liver metabolism and NAFLD pathogenesis

Aberrant gene expression induced by a high fat diet is linked to H3K9 acetylation in the promoter-proximal region

Sex- and age-associated factors drive the pathophysiology of MASLD

Novel targets and therapeutic strategies for type 2 diabetes

Administration of Helper-Dependent Adenoviral Vectors and Sequential Delivery of Different Vector Serotype for Long-Term Liver-Directed Gene Transfer in Baboons

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver

Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies

Gene targets of mouse miR-709: regulation of distinct pools

Enhancing hepatic mitochondrial fatty acid oxidation stimulates eating in food-deprived mice

Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the livers

Insights from a high-fat diet fed mouse model with a humanized liver

Helper-dependent Adenovirus-mediated Short Hairpin RNA Expression in the Liver Activates the Interferon Response

Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes

Hepatic insulin expression improves glycemic control in type 1 diabetic rats

Robust hepatic gene silencing for functional studies using helper-dependent adenoviral vectors

Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors

Gene therapy for inherited retinal and optic nerve degenerations

Constitutive expression of short hairpin RNA in vivo triggers buildup of mature hairpin molecules

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice

Gene therapy for age-related macular degeneration

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

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