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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR

Cellular and molecular life sciences : CMLS, 2021-12, Vol.78 (23), p.7813-7829

2021

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Order in Disorder as Observed by the “Hydrophobic Cluster Analysis” of Protein Sequences

Proteomics (Weinheim), 2018-11, Vol.18 (21-22), p.e1800054-n/a

2018

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Combining theoretical and experimental data to decipher CFTR 3D structures and functions

Cellular and molecular life sciences : CMLS, 2018-10, Vol.75 (20), p.3829-3855

2018

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Molecular models of the open and closed states of the whole human CFTR protein

Cellular and molecular life sciences : CMLS, 2009-11, Vol.66 (21), p.3469-3486

2009

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Cis variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules

Human mutation, 2018-04, Vol.39 (4), p.506-514

2018

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Digging into the 3D Structure Predictions of AlphaFold2 with Low Confidence: Disorder and Beyond

Biomolecules (Basel, Switzerland), 2022-10, Vol.12 (10), p.1467

2022

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The respective roles of polar/nonpolar binary patterns and amino acid composition in protein regular secondary structures explored exhaustively using hydrophobic cluster analysis

Proteins, structure, function, and bioinformatics, 2016-05, Vol.84 (5), p.624-638

2016

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Structure-Function Analysis of the Human Ferroportin Iron Exporter (SLC40A1): Effect of Hemochromatosis Type 4 Disease Mutations and Identification of Critical Residues

Human mutation, 2013-10, Vol.34 (10), p.1371-1380

2013

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Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants

International journal of molecular sciences, 2022-12, Vol.23 (24), p.16225

2022

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Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Frontiers in pharmacology, 2020-03, Vol.11, p.295-295

2020

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Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family

Nucleic acids research, 2002-08, Vol.30 (16), p.3592-3601

2002

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Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation

Scientific reports, 2021-09, Vol.11 (1), p.18709-18709, Article 18709

2021

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Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes

BMC genomics, 2005-07, Vol.6 (1), p.100-100, Article 100

2005

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Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics

Cellular and molecular life sciences : CMLS, 2015-04, Vol.72 (7), p.1377-1403

2015

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The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Nature cell biology, 2005-07, Vol.7 (7), p.698-705

2005

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Molecular modelling and molecular dynamics of CFTR

Cellular and molecular life sciences : CMLS, 2017-01, Vol.74 (1), p.3-22

2017

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Isolated ZP-N domains constitute the N-terminal extensions of Zona Pellucida proteins

Bioinformatics, 2007-08, Vol.23 (15), p.1871-1874

2007

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The implications of CFTR structural studies for cystic fibrosis drug development

Current opinion in pharmacology, 2017-06, Vol.34, p.112-118

2017

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Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF

The Journal of biological chemistry, 2010-08, Vol.285 (34), p.26475-26483

2010

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The Ig-like Structure of the C-Terminal Domain of Lamin A/C, Mutated in Muscular Dystrophies, Cardiomyopathy, and Partial Lipodystrophy

Structure (London), 2002-06, Vol.10 (6), p.811-823

2002

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A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family

Bioinformatics, 2009-05, Vol.25 (10), p.1219-1222

2009

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LOTUS, a new domain associated with small RNA pathways in the germline

Bioinformatics, 2010-05, Vol.26 (9), p.1140-1144

2010

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Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity

Molecular and Cellular Biology, 2007-07, Vol.27 (13), p.4774-4783

2007

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Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode

Acta crystallographica. Section D, Biological crystallography., 2004-03, Vol.60 (3), p.453-462

2004

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Protein secondary structure assignment through Voronoï tessellation

Proteins, structure, function, and bioinformatics, 2004-05, Vol.55 (3), p.519-528

2004

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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR

Order in Disorder as Observed by the “Hydrophobic Cluster Analysis” of Protein Sequences

Combining theoretical and experimental data to decipher CFTR 3D structures and functions

Molecular models of the open and closed states of the whole human CFTR protein

Cis variants identified in F508del complex alleles modulate CFTR channel rescue by small molecules

Digging into the 3D Structure Predictions of AlphaFold2 with Low Confidence: Disorder and Beyond

The respective roles of polar/nonpolar binary patterns and amino acid composition in protein regular secondary structures explored exhaustively using hydrophobic cluster analysis

Structure-Function Analysis of the Human Ferroportin Iron Exporter (SLC40A1): Effect of Hemochromatosis Type 4 Disease Mutations and Identification of Critical Residues

Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants

Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Metallo-beta-lactamase fold within nucleic acids processing enzymes: the beta-CASP family

Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation

Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes

Full-open and closed CFTR channels, with lateral tunnels from the cytoplasm and an alternative position of the F508 region, as revealed by molecular dynamics

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Molecular modelling and molecular dynamics of CFTR

Isolated ZP-N domains constitute the N-terminal extensions of Zona Pellucida proteins

The implications of CFTR structural studies for cystic fibrosis drug development

Delineation of the Xrcc4-interacting Region in the Globular Head Domain of Cernunnos/XLF

The Ig-like Structure of the C-Terminal Domain of Lamin A/C, Mutated in Muscular Dystrophies, Cardiomyopathy, and Partial Lipodystrophy

A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family

LOTUS, a new domain associated with small RNA pathways in the germline

Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity

Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode

Protein secondary structure assignment through Voronoï tessellation

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