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Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.1649-1654

2017

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Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

The Journal of biological chemistry, 2014-02, Vol.289 (7), p.4432-4443

2014

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Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

mBio, 2017-04, Vol.8 (2)

2017

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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Nature chemical biology, 2016-04, Vol.12 (4), p.218-225

2016

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.17010-17015

2012

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.17016-17021

2012

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Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

The Journal of biological chemistry, 2014-07, Vol.289 (30), p.20583-20593

2014

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Discovery of a Neuroprotective Chemical, (S)‑N‑(3-(3,6-Dibromo‑9H‑carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved Druglike Properties

Journal of medicinal chemistry, 2014-05, Vol.57 (9), p.3746-3754

2014

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Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors

Journal of medicinal chemistry, 2017-02, Vol.60 (3), p.1142-1150

2017

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Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9728-9733

2013

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Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)

Journal of medicinal chemistry, 2019-05, Vol.62 (10), p.5217-5241

2019

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Discovery and Optimization of N‑Arylated Tetracyclic Dicarboximides That Target Primary Glioma Stem-like Cells

Journal of medicinal chemistry, 2024-05, Vol.67 (11), p.9277-9301

2024

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Development of Proneurogenic, Neuroprotective Small Molecules

Journal of the American Chemical Society, 2011-02, Vol.133 (5), p.1428-1437

2011

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A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma

Science translational medicine, 2012-06, Vol.4 (137), p.137ra75

2012

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Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243

Investigative ophthalmology & visual science, 2014-12, Vol.55 (12), p.8330-8341

2014

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Development of a triazole class of highly potent Porcn inhibitors

Bioorganic & medicinal chemistry letters, 2016-12, Vol.26 (24), p.5891-5895

2016

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Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

Cell metabolism, 2015-01, Vol.21 (1), p.117-125

2015

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Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9

EBioMedicine, 2019-01, Vol.39, p.145-158

2019

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Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxyp y ridin-2-amine [(-)-P7C3-S243], with Improved Druglike Properties

Journal of medicinal chemistry, 2014-04, Vol.57 (9), p.3746-3754

2014

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Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease

NPJ Parkinson's Disease, 2015-01, Vol.1 (1), p.15010, Article 15010

2015

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Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9Research in the context

EBioMedicine, 2019-01, Vol.39, p.145-158

2019

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Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain [alpha]-ketoacid dehydrogenase kinase

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9728

2013

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Reliability and Factorial Validity of the Student Development Inventory

Educational and psychological measurement, 1985-09, Vol.45 (3), p.671-677

1985

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Preference Scaling of Titles in English Composition

The Journal of educational research (Washington, D.C.), 1968-05, Vol.61 (9), p.395-397

Jackson, Lorraine Morlock

1968

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Available Research Methods to Study Gender Role in Communication

Women's studies in communication, 1984-10, Vol.7 (2), p.86-90

Jackson, Lorraine Morlock

1984

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Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Benzothiophene Carboxylate Derivatives as Novel Allosteric Inhibitors of Branched-chain α-Ketoacid Dehydrogenase Kinase

Discovery of a Neuroprotective Chemical, (S)‑N‑(3-(3,6-Dibromo‑9H‑carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(−)-P7C3-S243], with Improved Druglike Properties

Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors

Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase

Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC)

Discovery and Optimization of N‑Arylated Tetracyclic Dicarboximides That Target Primary Glioma Stem-like Cells

Development of Proneurogenic, Neuroprotective Small Molecules

A validated tumorgraft model reveals activity of dovitinib against renal cell carcinoma

Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243

Development of a triazole class of highly potent Porcn inhibitors

Diet-Induced Unresolved ER Stress Hinders KRAS-Driven Lung Tumorigenesis

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9

Discovery of a Neuroprotective Chemical, (S)-N-(3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxyp y ridin-2-amine [(-)-P7C3-S243], with Improved Druglike Properties

Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease

Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9Research in the context

Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain [alpha]-ketoacid dehydrogenase kinase

Reliability and Factorial Validity of the Student Development Inventory

Preference Scaling of Titles in English Composition

Available Research Methods to Study Gender Role in Communication

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