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Cell Size Determines the Strength of the Spindle Assembly Checkpoint during Embryonic Development

Developmental cell, 2016-02, Vol.36 (3), p.344-352

2016

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Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex

Molecular cell, 2016-10, Vol.64 (1), p.12-23

2016

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Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

Molecular cell, 2020-12, Vol.80 (6), p.1092-1103.e4

2020

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The APC/C Subunit Mnd2/Apc15 Promotes Cdc20 Autoubiquitination and Spindle Assembly Checkpoint Inactivation

Molecular cell, 2012-09, Vol.47 (6), p.921-932

2012

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Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

Molecular cell, 2011-06, Vol.42 (5), p.610-623

2011

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Structural basis of human separase regulation by securin and CDK1-cyclin B1

Nature (London), 2021-08, Vol.596 (7870), p.138-142

2021

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Polyanions provide selective control of APC/C interactions with the activator subunit

Nature communications, 2019-12, Vol.10 (1), p.5807-12, Article 5807

2019

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Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C

Nature communications, 2022-01, Vol.13 (1), p.341-341, Article 341

2022

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Cdk1-Dependent Destruction of Eco1 Prevents Cohesion Establishment after S Phase

Molecular cell, 2011-05, Vol.42 (3), p.378-389

2011

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Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction

Current biology, 2017-09, Vol.27 (18), p.2849-2855.e2

2017

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Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates

Nature, 2005-03, Vol.434 (7029), p.104-108

2005

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Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (5), p.1442-1447

2008

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Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC

Nature medicine, 2007-07, Vol.13 (7), p.820-827

2007

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CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors

Annual review of cell and developmental biology, 1997-01, Vol.13 (1), p.261-291

Morgan, David O

1997

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Activation of the APC/C Ubiquitin Ligase by Enhanced E2 Efficiency

Current biology, 2014-07, Vol.24 (13), p.1556-1562

2014

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Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site

Nature communications, 2019-11, Vol.10 (1), p.5189-10, Article 5189

2019

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Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

The Journal of cell biology, 2014-10, Vol.207 (1), p.23-39

2014

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Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis

Journal of cell science, 2014-03, Vol.127 (Pt 5), p.1128-1137

2014

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Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase

Nature cell biology, 2007-01, Vol.9 (1), p.106-112

2007

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The D Box Meets Its Match

Molecular cell, 2013-06, Vol.50 (5), p.609-610

Morgan, David O.

2013

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Targets of the cyclin-dependent kinase Cdk1

Nature, 2003-10, Vol.425 (6960), p.859-864

2003

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Regulation of the APC and the exit from mitosis

Nature cell biology, 1999-06, Vol.1 (2), p.E47-E53

Morgan, David O

1999

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Ubiquitination of Cdc20 by the APC Occurs through an Intramolecular Mechanism

Current biology, 2011-11, Vol.21 (22), p.1870-1877

2011

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Control of mitosis by changes in the subcellular location of cyclin-B1–Cdk1 and Cdc25C

Current Opinion in Cell Biology, 2000-12, Vol.12 (6), p.658-665

2000

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The molecular mechanisms of human separase regulation

Biochemical Society transactions, 2023-06, Vol.51 (3), p.1225-1233

2023

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Cell Size Determines the Strength of the Spindle Assembly Checkpoint during Embryonic Development

Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex

Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions

The APC/C Subunit Mnd2/Apc15 Promotes Cdc20 Autoubiquitination and Spindle Assembly Checkpoint Inactivation

Dynamics of Cdk1 Substrate Specificity during the Cell Cycle

Structural basis of human separase regulation by securin and CDK1-cyclin B1

Polyanions provide selective control of APC/C interactions with the activator subunit

Single-molecule analysis of specificity and multivalency in binding of short linear substrate motifs to the APC/C

Cdk1-Dependent Destruction of Eco1 Prevents Cohesion Establishment after S Phase

Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction

Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates

Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC

CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors

Activation of the APC/C Ubiquitin Ligase by Enhanced E2 Efficiency

Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site

Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

Cdk1-dependent phosphorylation of Iqg1 governs actomyosin ring assembly prior to cytokinesis

Cdk and APC activities limit the spindle-stabilizing function of Fin1 to anaphase

The D Box Meets Its Match

Targets of the cyclin-dependent kinase Cdk1

Regulation of the APC and the exit from mitosis

Ubiquitination of Cdc20 by the APC Occurs through an Intramolecular Mechanism

Control of mitosis by changes in the subcellular location of cyclin-B1–Cdk1 and Cdc25C

The molecular mechanisms of human separase regulation

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