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Applying a weight of evidence approach to the evaluation of developmental toxicity of biopharmaceuticals

Regulatory toxicology and pharmacology, 2018-10, Vol.98, p.69-79

2018

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Current Topics in Postnatal Behavioral Testing

International journal of toxicology, 2016-09, Vol.35 (5), p.499-520

2016

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Interactions of dopamine D1 and D2 receptor antagonists with D-methamphetamine-induced hyperthermia and striatal dopamine and serotonin reductions

Synapse (New York, N.Y.), 2005-05, Vol.56 (2), p.84-93

2005

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3,4-Methylenedioxymethamphetamine (Ecstasy)-Induced Learning and Memory Impairments Depend on the Age of Exposure during Early Development

The Journal of neuroscience, 2001-05, Vol.21 (9), p.3228-3235

2001

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Preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals: strategy, challenges, current practices

Birth defects research. Part B. Developmental and reproductive toxicology, 2011-08, Vol.92 (4), p.359-380

2011

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Developmental D-methamphetamine treatment selectively induces spatial navigation impairments in reference memory in the Morris water maze while sparing working memory

Synapse (New York, N.Y.), 2003-06, Vol.48 (3), p.138-148

2003

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Hazard Identification and Predictability of Children's Health Risk from Animal Data

Environmental health perspectives, 2004-02, Vol.112 (2), p.266-271

2004

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Periadolescent rats (P41–50) exhibit increased susceptibility to d-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21–30 or P31–40) or adult rats (P51–60)

Neurotoxicology and teratology, 2005-01, Vol.27 (1), p.117-134

2005

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Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response

Brain research. Developmental brain research, 1997-11, Vol.103 (2), p.155-162

1997

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Effects of prenatal cocaine on Morris and Barnes maze tests of spatial learning and memory in the offspring of C57BL/6J mice

Neurotoxicology and teratology, 2000-07, Vol.22 (4), p.547-557

2000

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Evaluation of neonatal exposure to cocaine on learning, activity, startle, scent marking, immobility, and plasma cocaine concentrations

Neurotoxicology and teratology, 2000-03, Vol.22 (2), p.255-265

2000

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Adult Learning Deficits after Neonatal Exposure tod-Methamphetamine: Selective Effects on Spatial Navigation and Memory

The Journal of neuroscience, 2000-06, Vol.20 (12), p.4732-4739

2000

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Interactions of dopamine D 1 and D 2 receptor antagonists with D‐methamphetamine‐induced hyperthermia and striatal dopamine and serotonin reductions

Synapse (New York, N.Y.), 2005-05, Vol.56 (2), p.84-93

2005

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Enhancement of Cocaine-Induced Hyperthermia Fails to Elicit Neurotoxicity11Reviewed through the Neurochemistry Section, James P. O’Callaghan, Ph.D., Section Editor

Neurotoxicology and teratology, 1998-09, Vol.20 (5), p.531-535

1998

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Developmental 3,4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection stress

Brain research, 2003-04, Vol.968 (1), p.89-101

2003

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Adult Learning Deficits after Neonatal Exposure to D-Methamphetamine: Selective Effects on Spatial Navigation and Memory

The Journal of neuroscience, 2000-06, Vol.20 (12), p.4732-4739

2000

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Preweaning treatment with methamphetamine induces increases in both corticosterone and ACTH in rats

Neurotoxicology and teratology, 2000-09, Vol.22 (5), p.751-759

2000

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Administration of d,l-fenfluramine to rats produces learning deficits in the Cincinnati water maze but not the Morris water maze: relationship to adrenal cortical output

Neurotoxicology and teratology, 2002-11, Vol.24 (6), p.783-796

2002

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Prenatal Phenytoin Exposure and Spatial Navigation in Offspring: Effects on Reference and Working Memory and on Discrimination Learning

Neurotoxicology and teratology, 1999-09, Vol.21 (5), p.567-578

1999

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Enhancement of Cocaine-Induced Hyperthermia Fails to Elicit Neurotoxicity

Neurotoxicology and teratology, 1998-09, Vol.20 (5), p.531-535

1998

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Elevations in plasmatic titers of corticosterone and aldosterone, in the absence of changes in ACTH, testosterone, or glial fibrillary acidic protein, 72 h following d,l-fenfluramine or d-fenfluramine administration to rats

Neurotoxicology and teratology, 2001, Vol.23 (1), p.23-32

2001

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Prenatal Phenytoin Exposure and Spatial Navigation in Offspring

Neurotoxicology and teratology, 1999-09, Vol.21 (5), p.567-578

1999

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Evaluation of neonatal exposure to cocaine on learning, activity, startle, scent marking, immobility, and plasma cocaine concentrations☆☆This manuscript was reviewed through the Developmental Neurotoxicology section, Charles F. Mactutus, Ph.D., Guest Editor

Neurotoxicology and teratology, 2000-03, Vol.22 (2), p.255-265

2000

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Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug

Behavioral and brain functions, 2011-10, Vol.7 (1), p.41-41

2011

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Rethinking developmental toxicity testing: Evolution or revolution?

Birth defects research, 2018-06, Vol.110 (10), p.840-850

2018

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Applying a weight of evidence approach to the evaluation of developmental toxicity of biopharmaceuticals

Current Topics in Postnatal Behavioral Testing

Interactions of dopamine D1 and D2 receptor antagonists with D-methamphetamine-induced hyperthermia and striatal dopamine and serotonin reductions

3,4-Methylenedioxymethamphetamine (Ecstasy)-Induced Learning and Memory Impairments Depend on the Age of Exposure during Early Development

Preclinical safety evaluations supporting pediatric drug development with biopharmaceuticals: strategy, challenges, current practices

Developmental D-methamphetamine treatment selectively induces spatial navigation impairments in reference memory in the Morris water maze while sparing working memory

Hazard Identification and Predictability of Children's Health Risk from Animal Data

Periadolescent rats (P41–50) exhibit increased susceptibility to d-methamphetamine-induced long-term spatial and sequential learning deficits compared to juvenile (P21–30 or P31–40) or adult rats (P51–60)

Ontogeny of methamphetamine-induced neurotoxicity and associated hyperthermic response

Effects of prenatal cocaine on Morris and Barnes maze tests of spatial learning and memory in the offspring of C57BL/6J mice

Evaluation of neonatal exposure to cocaine on learning, activity, startle, scent marking, immobility, and plasma cocaine concentrations

Adult Learning Deficits after Neonatal Exposure tod-Methamphetamine: Selective Effects on Spatial Navigation and Memory

Interactions of dopamine D 1 and D 2 receptor antagonists with D‐methamphetamine‐induced hyperthermia and striatal dopamine and serotonin reductions

Enhancement of Cocaine-Induced Hyperthermia Fails to Elicit Neurotoxicity11Reviewed through the Neurochemistry Section, James P. O’Callaghan, Ph.D., Section Editor

Developmental 3,4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection stress

Adult Learning Deficits after Neonatal Exposure to D-Methamphetamine: Selective Effects on Spatial Navigation and Memory

Preweaning treatment with methamphetamine induces increases in both corticosterone and ACTH in rats

Administration of d,l-fenfluramine to rats produces learning deficits in the Cincinnati water maze but not the Morris water maze: relationship to adrenal cortical output

Prenatal Phenytoin Exposure and Spatial Navigation in Offspring: Effects on Reference and Working Memory and on Discrimination Learning

Enhancement of Cocaine-Induced Hyperthermia Fails to Elicit Neurotoxicity

Elevations in plasmatic titers of corticosterone and aldosterone, in the absence of changes in ACTH, testosterone, or glial fibrillary acidic protein, 72 h following d,l-fenfluramine or d-fenfluramine administration to rats

Prenatal Phenytoin Exposure and Spatial Navigation in Offspring

Evaluation of neonatal exposure to cocaine on learning, activity, startle, scent marking, immobility, and plasma cocaine concentrations☆☆This manuscript was reviewed through the Developmental Neurotoxicology section, Charles F. Mactutus, Ph.D., Guest Editor

Effects of periadolescent fluoxetine and paroxetine on elevated plus-maze, acoustic startle, and swimming immobility in rats while on and off-drug

Rethinking developmental toxicity testing: Evolution or revolution?

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