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Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases

Neurobiology of disease, 2017-09, Vol.105, p.273-282

2017

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Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease

Brain (London, England : 1878), 2012-07, Vol.135 (Pt 7), p.2058-2073

2012

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Axonal Transport Defects in Neurodegenerative Diseases

The Journal of neuroscience, 2009-10, Vol.29 (41), p.12776-12786

2009

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Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features

Journal of neurochemistry, 2010-06, Vol.113 (5), p.1073-1091

2010

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Tau: A Signaling Hub Protein

Frontiers in molecular neuroscience, 2021-03, Vol.14, p.647054-647054

2021

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Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

Nature neuroscience, 2009-07, Vol.12 (7), p.864-871

2009

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Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

Human molecular genetics, 2015-09, Vol.24 (18), p.5285-5298

2015

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Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase

PloS one, 2013-06, Vol.8 (6), p.e65235

2013

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Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

PloS one, 2017-12, Vol.12 (12), p.e0188340

2017

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Neuropathogenic Forms of Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport

Neuron (Cambridge, Mass.), 2003-09, Vol.40 (1), p.41-52

2003

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Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited

The Journal of neuroscience, 2005-03, Vol.25 (9), p.2386-2395

2005

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Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system

Experimental neurology, 2013-08, Vol.246, p.44-53

2013

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Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

The Journal of neuroscience, 2011-07, Vol.31 (27), p.9858-9868

2011

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Toxic effects of mutant huntingtin in axons are mediated by its proline-rich domain

Brain (London, England : 1878), 2024-06, Vol.147 (6), p.2098-2113

2024

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Phosphoregulation of Tau modulates inhibition of kinesin-1 motility

Molecular biology of the cell, 2017-04, Vol.28 (8), p.1079-1087

2017

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Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism

The Journal of neuroscience, 2021-11, Vol.41 (45), p.9431-9451

2021

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EGF Treatment Improves Motor Behavior and Cortical GABAergic Function in the R6/2 Mouse Model of Huntington’s Disease

Molecular neurobiology, 2019-11, Vol.56 (11), p.7708-7718

2019

Volltextzugriff (PDF)

Impairments in Fast Axonal Transport and Motor Neuron Deficits in Transgenic Mice Expressing Familial Alzheimer's Disease-Linked Mutant Presenilin 1

The Journal of neuroscience, 2007-06, Vol.27 (26), p.7011-7020

2007

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Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease

Journal of Parkinson's disease, 2016-01, Vol.6 (1), p.77

2016

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Regulation of Axonal Transport by Kinesin Phosphorylation at S176

Biophysical journal, 2012-01, Vol.102 (3), p.370a-370a

2012

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Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system: Axonal degeneration

Experimental neurology, 2013, Vol.246, p.44-53

2013

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Measuring Tau's Effect on Kinesin Motility in Model Systems for Axonal Transport

Biophysical journal, 2011-02, Vol.100 (3), p.449a-449a

2011

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Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

Nature neuroscience, 2009-07, Vol.12 (7), p.874

2009

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Chapter 7 - Intracellular Trafficking

Basic Neurochemistry, p.119-145

Volltextzugriff (PDF)

Chapter 8 - Axonal Transport

Basic Neurochemistry, p.146-164

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Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease

Axonal Transport Defects in Neurodegenerative Diseases

Differential vulnerability of neurons in Huntington's disease: the role of cell type-specific features

Tau: A Signaling Hub Protein

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease

Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase

Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

Neuropathogenic Forms of Huntingtin and Androgen Receptor Inhibit Fast Axonal Transport

Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited

Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

Toxic effects of mutant huntingtin in axons are mediated by its proline-rich domain

Phosphoregulation of Tau modulates inhibition of kinesin-1 motility

Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism

EGF Treatment Improves Motor Behavior and Cortical GABAergic Function in the R6/2 Mouse Model of Huntington’s Disease

Impairments in Fast Axonal Transport and Motor Neuron Deficits in Transgenic Mice Expressing Familial Alzheimer's Disease-Linked Mutant Presenilin 1

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease

Regulation of Axonal Transport by Kinesin Phosphorylation at S176

Axonal degeneration in Alzheimer's disease: When signaling abnormalities meet the axonal transport system: Axonal degeneration

Measuring Tau's Effect on Kinesin Motility in Model Systems for Axonal Transport

Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin

Chapter 7 - Intracellular Trafficking

Chapter 8 - Axonal Transport

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