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Translocation of Sphingosine Kinase 1 to the Plasma Membrane Is Mediated by Calcium- and Integrin-binding Protein 1

The Journal of biological chemistry, 2010-01, Vol.285 (1), p.483-492

2010

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The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism

Scientific reports, 2022-01, Vol.12 (1), p.454-454, Article 454

2022

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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Blood, 2017-02, Vol.129 (6), p.771-782

2017

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Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma

Oncogene, 2019-02, Vol.38 (8), p.1151-1165

2019

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CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4823-4834

2017

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A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis

Developmental cell, 2015-12, Vol.35 (6), p.759-774

2015

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Eukaryotic Elongation Factor 1A Interacts with Sphingosine Kinase and Directly Enhances Its Catalytic Activity

The Journal of biological chemistry, 2008-04, Vol.283 (15), p.9606-9614

2008

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The Calmodulin-binding Site of Sphingosine Kinase and Its Role in Agonist-dependent Translocation of Sphingosine Kinase 1 to the Plasma Membrane

The Journal of biological chemistry, 2006-04, Vol.281 (17), p.11693-11701

2006

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Deactivation of Sphingosine Kinase 1 by Protein Phosphatase 2A

The Journal of biological chemistry, 2008-12, Vol.283 (50), p.34994-35002

2008

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Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody

EMBO reports, 2022-04, Vol.23 (4), p.e52904-n/a

2022

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Sphingosine 1‐phosphate is a ligand for peroxisome proliferator‐activated receptor‐γ that regulates neoangiogenesis

The FASEB journal, 2015-09, Vol.29 (9), p.3638-3653

2015

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Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1

Biochemical journal, 2019-11, Vol.476 (21), p.3211-3226

2019

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Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

Oncotarget, 2017-07, Vol.8 (27), p.43602-43616

2017

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Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3′ AU-rich mRNA destabilizing elements

BioTechniques, 2008-08, Vol.45 (2), p.155-162

2008

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A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties

Oncotarget, 2015-03, Vol.6 (9), p.7065-7083

2015

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An oncogenic role for sphingosine kinase 2

Oncotarget, 2016-10, Vol.7 (40), p.64886-64899

2016

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A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1

The international journal of biochemistry & cell biology, 2011-03, Vol.43 (3), p.342-347

2011

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The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1

The international journal of biochemistry & cell biology, 2009-04, Vol.41 (4), p.822-827

2009

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Over-Expression of Sphingosine Kinase-1 Enhances a Progenitor Phenotype in Human Endothelial Cells

Microcirculation (New York, N.Y. 1994), 2011-10, Vol.18 (7), p.583-597

2011

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The Nucleotide-binding Site of Human Sphingosine Kinase 1

The Journal of biological chemistry, 2002-12, Vol.277 (51), p.49545-49553

2002

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CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1

Oncogene, 2017-05, Vol.36 (18), p.2619-2627

2017

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Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

The EMBO journal, 2003-10, Vol.22 (20), p.5491-5500

2003

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Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

The Journal of experimental medicine, 2005-01, Vol.201 (1), p.49-54

2005

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Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling

The Journal of biological chemistry, 2002-03, Vol.277 (10), p.7996-8003

2002

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Translocation of Sphingosine Kinase 1 to the Plasma Membrane Is Mediated by Calcium- and Integrin-binding Protein 1

The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma

CIB2 Negatively Regulates Oncogenic Signaling in Ovarian Cancer via Sphingosine Kinase 1

A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis

Eukaryotic Elongation Factor 1A Interacts with Sphingosine Kinase and Directly Enhances Its Catalytic Activity

The Calmodulin-binding Site of Sphingosine Kinase and Its Role in Agonist-dependent Translocation of Sphingosine Kinase 1 to the Plasma Membrane

Deactivation of Sphingosine Kinase 1 by Protein Phosphatase 2A

Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody

Sphingosine 1‐phosphate is a ligand for peroxisome proliferator‐activated receptor‐γ that regulates neoangiogenesis

Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

Attenuation of leakiness in doxycycline-inducible expression via incorporation of 3′ AU-rich mRNA destabilizing elements

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties

An oncogenic role for sphingosine kinase 2

A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1

The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1

Over-Expression of Sphingosine Kinase-1 Enhances a Progenitor Phenotype in Human Endothelial Cells

The Nucleotide-binding Site of Human Sphingosine Kinase 1

CIB1 contributes to oncogenic signalling by Ras via modulating the subcellular localisation of sphingosine kinase 1

Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation

Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signalling

Sphingosine Kinase Interacts with TRAF2 and Dissects Tumor Necrosis Factor-α Signaling

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