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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Nature immunology, 2016-03, Vol.17 (3), p.250-258

2016

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Sulfatides are endogenous ligands for the TLR4–MD-2 complex

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30), p.1-12

2021

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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.E884-E893

2016

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N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization

Nature communications, 2021-03, Vol.12 (1), p.1379-12, Article 1379

2021

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IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1196-E1204

2017

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HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3263-3277

2017

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Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Journal of medicinal chemistry, 2019-03, Vol.62 (6), p.2938-2949

2019

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Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9

Immunity (Cambridge, Mass.), 2011-04, Vol.34 (4), p.453-455

2011

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OVOL2 sustains postnatal thymic epithelial cell identity

Nature communications, 2023-11, Vol.14 (1), p.7786-7786, Article 7786

2023

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Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

Science (American Association for the Advancement of Science), 2008-05, Vol.320 (5879), p.1088-1092

2008

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Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

Nature communications, 2022-07, Vol.13 (1), p.4136-4136, Article 4136

2022

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LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6440)

2019

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Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

Nature communications, 2023-06, Vol.14 (1), p.3652-13, Article 3652

2023

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Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Journal of the American Chemical Society, 2018-10, Vol.140 (43), p.14440-14454

2018

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Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.12931-12942

2020

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Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Nature communications, 2018-01, Vol.9 (1), p.441-10, Article 441

2018

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Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11380-11389

2019

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De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (47), p.1-7

2021

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E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration

Scientific reports, 2024-02, Vol.14 (1), p.3010-3010, Article 3010

2024

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Real-time resolution of point mutations that cause phenovariance in mice

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (5), p.E440-E449

2015

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Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (15), p.8563-8572

2020

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Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40

Nature immunology, 2019-10, Vol.20 (10), p.1322-1334

2019

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Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (28), p.1-11

2021

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Toll-like receptors

Current biology, 2011-07, Vol.21 (13), p.R488-R493

2011

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The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

Disease models & mechanisms, 2023-09, Vol.16 (9)

2023

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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Sulfatides are endogenous ligands for the TLR4–MD-2 complex

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization

IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections

Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9

OVOL2 sustains postnatal thymic epithelial cell identity

Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration

Real-time resolution of point mutations that cause phenovariance in mice

Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40

Thousands of induced germline mutations affecting immune cells identified by automated meiotic mapping coupled with machine learning

Toll-like receptors

The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation

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