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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Nature immunology, 2016-03, Vol.17 (3), p.250

2016

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Sulfatides are endogenous ligands for the TLR4-MD-2 complex

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (30)

2021

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TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.E884-E893

2016

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N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization

Nature communications, 2021-03, Vol.12 (1), p.1379-12, Article 1379

2021

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Essential requirement for IER3IP1 in B cell development

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (46), p.e2312810120-e2312810120

2023

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OVOL2 sustains postnatal thymic epithelial cell identity

Nature communications, 2023-11, Vol.14 (1), p.7786-7786, Article 7786

2023

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Viable mutations of mouse midnolin suppress B cell malignancies

The Journal of experimental medicine, 2024-06, Vol.221 (6)

2024

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Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Journal of medicinal chemistry, 2019-03, Vol.62 (6), p.2938-2949

2019

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Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

Nature communications, 2023-06, Vol.14 (1), p.3652-13, Article 3652

2023

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IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.E1196-E1204

2017

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LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6440)

2019

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Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

Science (American Association for the Advancement of Science), 2008-05, Vol.320 (5879), p.1088-1092

2008

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Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice

Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.E8698-E8706

2018

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MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

Science (American Association for the Advancement of Science), 2014-12, Vol.346 (6216), p.1486-1492

2014

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Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

Nature communications, 2022-07, Vol.13 (1), p.4136-4136, Article 4136

2022

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SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity

Science (American Association for the Advancement of Science), 2021-05, Vol.372 (6543)

2021

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Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Journal of the American Chemical Society, 2018-10, Vol.140 (43), p.14440-14454

2018

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Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.12931-12942

2020

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Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis

Proceedings of the National Academy of Sciences - PNAS, 2023-12, Vol.120 (50), p.e2314429120-e2314429120

2023

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Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11380-11389

2019

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De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (47), p.1

2021

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Going forward with genetics: recent technological advances and forward genetics in mice

The American journal of pathology, 2013-05, Vol.182 (5), p.1462-1473

2013

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Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Nature communications, 2018-01, Vol.9 (1), p.441-10, Article 441

2018

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Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40

Nature immunology, 2019-10, Vol.20 (10), p.1322

2019

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HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections

The Journal of experimental medicine, 2017-11, Vol.214 (11), p.3263-3277

2017

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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

Sulfatides are endogenous ligands for the TLR4-MD-2 complex

TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS

N4BP1 negatively regulates NF-κB by binding and inhibiting NEMO oligomerization

Essential requirement for IER3IP1 in B cell development

OVOL2 sustains postnatal thymic epithelial cell identity

Viable mutations of mouse midnolin suppress B cell malignancies

Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim

Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation

IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency

Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti–PD-L1 to eliminate melanoma in mice

MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses

Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity

SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity

Diprovocims: A New and Exceptionally Potent Class of Toll-like Receptor Agonists

Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice

Essential role of MFSD1-GLMP-GIMAP5 in lymphocyte survival and liver homeostasis

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

Going forward with genetics: recent technological advances and forward genetics in mice

Probability of phenotypically detectable protein damage by ENU-induced mutations in the Mutagenetix database

Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40

HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections

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