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Integrins as therapeutic targets: lessons and opportunities

Nature reviews. Drug discovery, 2010-10, Vol.9 (10), p.804-820

2010

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COVID-19 induces a hyperactive phenotype in circulating platelets

PLoS biology, 2021-02, Vol.19 (2), p.e3001109-e3001109

2021

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Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene

Molecular cancer, 2012-02, Vol.11 (1), p.6-6, Article 6

2012

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Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

PloS one, 2019-01, Vol.14 (1), p.e0210337-e0210337

2019

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Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction

PloS one, 2013-02, Vol.8 (2), p.e57491-e57491

2013

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Peptides derived from cadherin juxtamembrane region inhibit platelet function

Royal Society open science, 2018-10, Vol.5 (10), p.172347-172347

2018

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The Non-Thrombotic Role of Platelets in Health and Disease

2015

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Case Report: Hypergranular Platelets in Vaccine-Induced Thrombotic Thrombocytopenia After ChAdOx1 nCov-19 Vaccination

Frontiers in cardiovascular medicine, 2022-02, Vol.9, p.824601

2022

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Poly(Ethylene glycol)-based backbones with high peptide loading capacities

Molecules (Basel, Switzerland), 2014-10, Vol.19 (11), p.17559-17577

2014

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Bioinformatic discovery of novel bioactive peptides

Nature chemical biology, 2007-02, Vol.3 (2), p.108-112

2007

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Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies

PLoS computational biology, 2015-04, Vol.11 (4), p.e1004119-e1004119

2015

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Cell Adhesion Molecules: Therapeutic Targets for Inhibition of Inflammatory States

Seminars in thrombosis and hemostasis, 2015-09, Vol.41 (6), p.563-571

2015

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A novel and essential role for FcγRIIa in cancer cell–induced platelet activation

Blood, 2014-01, Vol.123 (2), p.249-260

2014

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797: The effect of cigarette smoking on platelet function in early pregnancy

American journal of obstetrics and gynecology, 2020-01, Vol.222 (1), p.S504-S504

2020

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The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance

Cancers, 2017-10, Vol.9 (10), p.142

2017

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A Sequence within the Cytoplasmic Tail of GpIIb Independently Activates Platelet Aggregation and Thromboxane Synthesis

The Journal of biological chemistry, 1998-08, Vol.273 (32), p.20317-20322

1998

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089The Effects of Discrimination and Perceptions of Ageism on Community Participation among Older Adults

Age and ageing, 2017-09, Vol.46 (Suppl_3), p.iii1-iii12

2017

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Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging

Chemical communications (Cambridge, England), 2008-01 (42), p.5307-5309

2008

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Novel integrin-specific targets for anti-platelet therapies

Current pharmaceutical design, 2004-01, Vol.10 (14), p.1603-1609

2004

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Omega-3 index and blood pressure responses to eating foods naturally enriched with omega-3 polyunsaturated fatty acids: a randomized controlled trial

Scientific reports, 2020-09, Vol.10 (1), p.15444-15444, Article 15444

2020

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RGD Labeled Ru(II) Polypyridyl Conjugates for Platelet Integrin αIIbβ3 Recognition and as Reporters of Integrin Conformation

Bioconjugate chemistry, 2014-05, Vol.25 (5), p.928-944

2014

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Fibrinogen Motif Discriminates Platelet and Cell Capture in Peptide-Modified Gold Micropore Arrays

Langmuir, 2018-01, Vol.34 (2), p.715-725

2018

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A Novel Hemizygous Bernard-Soulier Syndrome (BSS) Mutation in the Amino Terminal Domain of Glycoprotein (GP)Ibβ- Platelet Characterization and Transfection Studies

Thrombosis and haemostasis, 2002-12, Vol.88 (12), p.1026-1032

2002

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Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα

Redox biology, 2015-12, Vol.6, p.640-647

2015

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Platelet Glycoprotein Gpiib-Iiia Complex - Metabolism
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Integrins as therapeutic targets: lessons and opportunities

COVID-19 induces a hyperactive phenotype in circulating platelets

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene

Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction

Peptides derived from cadherin juxtamembrane region inhibit platelet function

The Non-Thrombotic Role of Platelets in Health and Disease

Case Report: Hypergranular Platelets in Vaccine-Induced Thrombotic Thrombocytopenia After ChAdOx1 nCov-19 Vaccination

Poly(Ethylene glycol)-based backbones with high peptide loading capacities

Bioinformatic discovery of novel bioactive peptides

Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies

Cell Adhesion Molecules: Therapeutic Targets for Inhibition of Inflammatory States

A novel and essential role for FcγRIIa in cancer cell–induced platelet activation

797: The effect of cigarette smoking on platelet function in early pregnancy

The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance

A Sequence within the Cytoplasmic Tail of GpIIb Independently Activates Platelet Aggregation and Thromboxane Synthesis

089The Effects of Discrimination and Perceptions of Ageism on Community Participation among Older Adults

Ruthenium polypyridyl peptide conjugates: membrane permeable probes for cellular imaging

Novel integrin-specific targets for anti-platelet therapies

Omega-3 index and blood pressure responses to eating foods naturally enriched with omega-3 polyunsaturated fatty acids: a randomized controlled trial

RGD Labeled Ru(II) Polypyridyl Conjugates for Platelet Integrin αIIbβ3 Recognition and as Reporters of Integrin Conformation

Fibrinogen Motif Discriminates Platelet and Cell Capture in Peptide-Modified Gold Micropore Arrays

A Novel Hemizygous Bernard-Soulier Syndrome (BSS) Mutation in the Amino Terminal Domain of Glycoprotein (GP)Ibβ- Platelet Characterization and Transfection Studies

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα

‘On-treatment platelet reactivity’ under both high and low shear stress conditions and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis: Results from the HaEmostasis In carotid STenosis(HEIST) study. (P1.3-066)

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