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INTERLEUKIN-10 AND THE INTERLEUKIN-10 RECEPTOR

Annual review of immunology, 2001-01, Vol.19 (1), p.683-765

2001

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FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein

PloS one, 2013-04, Vol.8 (4), p.e61432

2013

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Differential IL-10R1 Expression Plays a Critical Role in IL-10-Mediated Immune Regulation

The Journal of immunology (1950), 2001-12, Vol.167 (12), p.6884-6892

2001

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Up-Regulation of IL-10R1 Expression Is Required to Render Human Neutrophils Fully Responsive to IL-10

The Journal of immunology (1950), 2001-08, Vol.167 (4), p.2312-2322

2001

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A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

The Journal of immunology (1950), 2002-06, Vol.168 (11), p.5699-5708

2002

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Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Immunity (Cambridge, Mass.), 2000-11, Vol.13 (5), p.715-725

2000

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Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains

Nature biotechnology, 2005-12, Vol.23 (12), p.1556-1561

2005

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Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

Science (American Association for the Advancement of Science), 1990-06, Vol.248 (4960), p.1230-1234

1990

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Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1

Science (American Association for the Advancement of Science), 1990-11, Vol.250 (4982), p.830-832

1990

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3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues: High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1807-1822

2004

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4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

Journal of medicinal chemistry, 1992-05, Vol.35 (11), p.1954-1968

1992

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Selective, Orally Active γ-Aminobutyric AcidA α5 Receptor Inverse Agonists as Cognition Enhancers

Journal of medicinal chemistry, 2004-04, Vol.47 (9), p.2176-2179

2004

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Pillars article: homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science. 1990. 248: 1230-1234

The Journal of immunology (1950), 2012-09, Vol.189 (5), p.2072-2076

2012

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Lymphotactin: A Cytokine That Represents a New Class of Chemokine

Science (American Association for the Advancement of Science), 1994-11, Vol.266 (5189), p.1395-1399

1994

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Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABAA Receptor Agonists at the α3 Subunit

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1367-1383

2005

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Synthesis and Biological Evaluation of 3-Heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and Analogues as Subtype-Selective Inverse Agonists for the GABAAα5 Benzodiazepine Binding Site

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3642-3657

2004

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Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1243-1252

1991

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Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain

The Journal of biological chemistry, 1996-11, Vol.271 (44), p.27954-27961

1996

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IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-18

The Journal of immunology (1950), 2000-11, Vol.165 (9), p.4950-4956

2000

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A Receptor for Interleukin 10 is Related to Interferon Receptors

Proceedings of the National Academy of Sciences - PNAS, 1993-12, Vol.90 (23), p.11267-11271

1993

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2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: Functionally selective GABAA α3-subtype agonists

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3550-3554

2006

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Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation

Journal of interferon & cytokine research, 2006-05, Vol.26 (5), p.281-290

2006

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2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor

Bioorganic & medicinal chemistry letters, 2004-07, Vol.14 (13), p.3441-3444

2004

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1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D4 Receptor with Excellent Selectivity over Ion Channels

Journal of medicinal chemistry, 1999-07, Vol.42 (14), p.2706-2715

1999

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INTERLEUKIN-10 AND THE INTERLEUKIN-10 RECEPTOR

FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein

Differential IL-10R1 Expression Plays a Critical Role in IL-10-Mediated Immune Regulation

Up-Regulation of IL-10R1 Expression Is Required to Render Human Neutrophils Fully Responsive to IL-10

A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12

Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains

Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI

Expression of Interleukin-10 Activity by Epstein-Barr Virus Protein BCRF1

3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues: High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2, α3, and α5-Subtype Binding Selectivity over α1

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

Selective, Orally Active γ-Aminobutyric AcidA α5 Receptor Inverse Agonists as Cognition Enhancers

Pillars article: homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science. 1990. 248: 1230-1234

Lymphotactin: A Cytokine That Represents a New Class of Chemokine

Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABAA Receptor Agonists at the α3 Subunit

Synthesis and Biological Evaluation of 3-Heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazines and Analogues as Subtype-Selective Inverse Agonists for the GABAAα5 Benzodiazepine Binding Site

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4- triazol-3-ylmethoxy)-3-(2-fluorophenyl)- 1,2,4-triazolo[4,3-b]pyridazine: A Functionally Selective γ-Aminobutyric AcidA (GABAA) α2/α3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models

Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain

IL-18 Receptors, Their Role in Ligand Binding and Function: Anti-IL-1RAcPL Antibody, a Potent Antagonist of IL-18

A Receptor for Interleukin 10 is Related to Interferon Receptors

2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: Functionally selective GABAA α3-subtype agonists

Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation

2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one: A Selective High-Affinity Antagonist for the Human Dopamine D4 Receptor with Excellent Selectivity over Ion Channels

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