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Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: a novel strategy to treat renal fibrosis

The Journal of pharmacology and experimental therapeutics, 2006-10, Vol.319 (1), p.8-19

2006

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Renal-selective delivery and angiotensin-converting enzyme inhibition by subcutaneously administered captopril-lysozyme

Drug metabolism and disposition, 2005-05, Vol.33 (5), p.683-688

2005

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Bioanalysis and pharmacokinetics of the p38 MAPkinase inhibitor SB202190 in rats

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-11, Vol.826 (1), p.220-225

2005

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Bioanalysis of captopril: two sensitive high-performance liquid chromatographic methods with pre- or postcolumn fluorescent labeling

Journal of chromatography. B, Biomedical sciences and applications, 1997-05, Vol.693 (1), p.181-189

1997

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Novel Therapeutic Targets for the Treatment of Tubulointerstitial Fibrosis

Current signal transduction therapy, 2008-05, Vol.3 (2), p.97-111

2008

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Inhibition of Renal Rho Kinase Attenuates Ischemia/ Reperfusion-Induced Injury

Journal of the American Society of Nephrology, 2008-11, Vol.19 (11), p.2086-2097

2008

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Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis

Pharmaceutical research, 2008-10, Vol.25 (10), p.2427-2439

2008

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Urine collection in the freely moving rat: Reliability for measurement of short-term renal effects

Journal of pharmacological and toxicological methods, 1997-09, Vol.38 (1), p.47-51

1997

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Basic understanding of pharmacokinetics that every doctor should know

Nederlands tijdschrift voor geneeskunde, 2009-01, Vol.153 (4), p.148

2009

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Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis : Targets in fibrotic disorders

Pharmaceutical research, 2008, Vol.25 (10), p.2427-2439

2008

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Specific drug delivery to the kidney

Cardiovascular drugs and therapy, 2002-12, Vol.16 (6), p.489-496

2002

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Bioavailability of morphine from suppositories

International journal of pharmaceutics, 1988-07, Vol.45 (1), p.161-164

1988

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Drug-targeting to the kidney: Renal delivery and degradation of a naproxen-lysozyme conjugate in vivo

Kidney international, 1997-12, Vol.52 (6), p.1693-1699

1997

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Renal targeting of captopril using captopril-lysozyme conjugate enhances its antiproteinuric effect in adriamycin-induced nephrosis

Journal of the renin-angiotensin-aldosterone system, 2004-12, Vol.5 (4), p.197-202

2004

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Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats

British journal of pharmacology, 2002-08, Vol.136 (8), p.1107-1116

2002

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Effects of anti-proteinuric therapy with angiotensin-converting-enzyme inhibition on renal protein catabolism in the adriamycin-induced nephrotic rat

Clinical science (1979), 2003-07, Vol.105 (1), p.51-57

2003

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Absorption rate and bioavailability of promethazine from rectal and oral dosage forms

International journal of pharmaceutics, 1981-01, Vol.9 (4), p.353-357

1981

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Targeting of Doxorubicin to the Urinary Bladder of the Rat Shows Increased Cytotoxicity in the Bladder Urine Combined With An Absence of Renal Toxicity

Journal of drug targeting, 2002, Vol.10 (1), p.81-89

2002

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POTENTIALS AND LIMITATIONS OF THE LOW-MOLECULAR-WEIGHT PROTEIN LYSOZYME AS A CARRIER FOR RENAL DRUG TARGETING

Renal failure, 2001-01, Vol.23 (3-4), p.397-409

2001

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Hepatic endocytosis of various types of mannose-terminated albumins. What is important, sugar recognition, net charge, or the combination of these features

The Journal of biological chemistry, 1991-02, Vol.266 (5), p.3343-3348

1991

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Renal targeting of a non-steroidal anti-inflammatory drug: effects on renal prostaglandin synthesis in the rat

Clinical science (1979), 1998-11, Vol.95 (5), p.603-609

1998

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Drug targeting to the kidney with low-molecular-weight proteins

Advanced drug delivery reviews, 1994-04, Vol.14 (1), p.67-88

1994

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Drug Delivery to the Kidneys and the Bladder with the Low Molecular Weight Protein Lysozyme

Renal failure, 1998-01, Vol.20 (2), p.211-217

1998

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Determination of dopaminergic prodrugs by high-performance liquid chromatography followed by post-column ion-pair extraction

Journal of chromatography. B, Biomedical sciences and applications, 1997-06, Vol.693 (2), p.484-488

1997

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Low-molecular-weight proteins as carriers for renal drug targeting. Preparation of drug-protein conjugates and drug-spacer derivatives and their catabolism in renal cortex homogenates and lysosomal lysates

Journal of medicinal chemistry, 1992-04, Vol.35 (7), p.1246-1259

1992

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Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: a novel strategy to treat renal fibrosis

Renal-selective delivery and angiotensin-converting enzyme inhibition by subcutaneously administered captopril-lysozyme

Bioanalysis and pharmacokinetics of the p38 MAPkinase inhibitor SB202190 in rats

Bioanalysis of captopril: two sensitive high-performance liquid chromatographic methods with pre- or postcolumn fluorescent labeling

Novel Therapeutic Targets for the Treatment of Tubulointerstitial Fibrosis

Inhibition of Renal Rho Kinase Attenuates Ischemia/ Reperfusion-Induced Injury

Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis

Urine collection in the freely moving rat: Reliability for measurement of short-term renal effects

Basic understanding of pharmacokinetics that every doctor should know

Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis : Targets in fibrotic disorders

Specific drug delivery to the kidney

Bioavailability of morphine from suppositories

Drug-targeting to the kidney: Renal delivery and degradation of a naproxen-lysozyme conjugate in vivo

Renal targeting of captopril using captopril-lysozyme conjugate enhances its antiproteinuric effect in adriamycin-induced nephrosis

Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats

Effects of anti-proteinuric therapy with angiotensin-converting-enzyme inhibition on renal protein catabolism in the adriamycin-induced nephrotic rat

Absorption rate and bioavailability of promethazine from rectal and oral dosage forms

Targeting of Doxorubicin to the Urinary Bladder of the Rat Shows Increased Cytotoxicity in the Bladder Urine Combined With An Absence of Renal Toxicity

POTENTIALS AND LIMITATIONS OF THE LOW-MOLECULAR-WEIGHT PROTEIN LYSOZYME AS A CARRIER FOR RENAL DRUG TARGETING

Hepatic endocytosis of various types of mannose-terminated albumins. What is important, sugar recognition, net charge, or the combination of these features

Renal targeting of a non-steroidal anti-inflammatory drug: effects on renal prostaglandin synthesis in the rat

Drug targeting to the kidney with low-molecular-weight proteins

Drug Delivery to the Kidneys and the Bladder with the Low Molecular Weight Protein Lysozyme

Determination of dopaminergic prodrugs by high-performance liquid chromatography followed by post-column ion-pair extraction

Low-molecular-weight proteins as carriers for renal drug targeting. Preparation of drug-protein conjugates and drug-spacer derivatives and their catabolism in renal cortex homogenates and lysosomal lysates

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