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Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

American journal of physiology. Lung cellular and molecular physiology, 2015-02, Vol.308 (4), p.L344-L357

2015

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TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression

American Journal of Physiology: Cell Physiology, 2017-03, Vol.312 (3), p.C277-C285

2017

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Determination of gastric emptying in nonobese diabetic mice

American journal of physiology: Gastrointestinal and liver physiology, 2007-11, Vol.293 (5), p.G1039-G1045

2007

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Vascular dysfunction in aged mice contributes to persistent lung fibrosis

Aging cell, 2020-08, Vol.19 (8), p.e13196-n/a

2020

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GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7

Journal of cellular physiology, 2021-11, Vol.236 (11), p.7759-7774

2021

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Heme Oxygenase-1 Protects Interstitial Cells of Cajal From Oxidative Stress and Reverses Diabetic Gastroparesis

Gastroenterology (New York, N.Y. 1943), 2008-12, Vol.135 (6), p.2055-2064.e2

2008

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RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation

Journal of cell science, 2018-05, Vol.131 (10), p.jcs209932-jcs209932

2018

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Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying

Gastroenterology (New York, N.Y. 1943), 2017-08, Vol.153 (2), p.521-535.e20

2017

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Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis

PloS one, 2017-11, Vol.12 (11), p.e0187772-e0187772

2017

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Non‐canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells

Physiological reports, 2024-04, Vol.12 (7), p.e15999-n/a

2024

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Comparison of the epidemiology and injury profile among injured patients involved in special purpose vehicle-related incidents in South Korea

Archives of environmental & occupational health, 2021, Vol.76 (1), p.23-30

2021

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Carbon monoxide reverses diabetic gastroparesis in NOD mice

American journal of physiology: Gastrointestinal and liver physiology, 2010-06, Vol.298 (6), p.G1013-G1019

2010

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Effects of aspirin & simvastatin and aspirin, simvastatin, & lipoic acid on heme oxygenase‐1 in healthy human subjects

Neurogastroenterology and motility, 2014-10, Vol.26 (10), p.1437-1442

2014

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Human airway organoid engineering as a step toward lung regeneration and disease modeling

Biomaterials, 2017-01, Vol.113, p.118-132

2017

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Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice

Cellular and molecular gastroenterology and hepatology, 2016-07, Vol.2 (4), p.454-467

2016

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Aging and anatomical variations in lung tissue stiffness

American journal of physiology. Lung cellular and molecular physiology, 2018-06, Vol.314 (6), p.L946-L955

2018

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Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

Science translational medicine, 2019-10, Vol.11 (516)

2019

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Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2

American journal of physiology. Lung cellular and molecular physiology, 2017-09, Vol.313 (3), p.L628-L647

2017

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TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

American journal of physiology. Lung cellular and molecular physiology, 2020-05, Vol.318 (5), p.L852-L863

2020

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Combined control of the fibroblast contractile program by YAP and TAZ

American journal of physiology. Lung cellular and molecular physiology, 2022-01, Vol.322 (1), p.L23-L32

2022

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CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice

Gastroenterology (New York, N.Y. 1943), 2010-06, Vol.138 (7), p.2399-2409.e1

2010

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Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1

Gastroenterology (New York, N.Y. 1943), 2015-08, Vol.149 (2), p.420-432.e16

2015

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CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis

JCI insight, 2019-06, Vol.5 (12)

2019

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Effects of hemin on heme oxygenase‐1, gastric emptying, and symptoms in diabetic gastroparesis

Neurogastroenterology and motility, 2016-11, Vol.28 (11), p.1731-1740

2016

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First-in-Human Study Demonstrating Pharmacological Activation of Heme Oxygenase-1 in Humans

Clinical pharmacology and therapeutics, 2010-02, Vol.87 (2), p.187-190

2010

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Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression

Determination of gastric emptying in nonobese diabetic mice

Vascular dysfunction in aged mice contributes to persistent lung fibrosis

GPCR‐mediated YAP/TAZ inactivation in fibroblasts via EPAC1/2, RAP2C, and MAP4K7

Heme Oxygenase-1 Protects Interstitial Cells of Cajal From Oxidative Stress and Reverses Diabetic Gastroparesis

RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation

Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying

Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis

Non‐canonical IKB kinases regulate YAP/TAZ and pathological vascular remodeling behaviors in pulmonary artery smooth muscle cells

Comparison of the epidemiology and injury profile among injured patients involved in special purpose vehicle-related incidents in South Korea

Carbon monoxide reverses diabetic gastroparesis in NOD mice

Effects of aspirin & simvastatin and aspirin, simvastatin, & lipoic acid on heme oxygenase‐1 in healthy human subjects

Human airway organoid engineering as a step toward lung regeneration and disease modeling

Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice

Aging and anatomical variations in lung tissue stiffness

Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis

Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2

TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation

Combined control of the fibroblast contractile program by YAP and TAZ

CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice

Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1

CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis

Effects of hemin on heme oxygenase‐1, gastric emptying, and symptoms in diabetic gastroparesis

First-in-Human Study Demonstrating Pharmacological Activation of Heme Oxygenase-1 in Humans

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