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Susceptibility of Leishmania to novel pentavalent organometallics: Investigating impact on DNA and membrane integrity in antimony(III)‐sensitive and ‐resistant strains

Drug development research, 2024-05, Vol.85 (3), p.e22194-n/a

2024

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Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery

Genes, 2020-06, Vol.11 (7), p.722

2020

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Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs

Cell biology international, 2022-11, Vol.46 (11), p.1947-1958

2022

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Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone

Chemical biology & drug design, 2021-01, Vol.97 (1), p.41-50

2021

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Recent research brings hope for reshaping the co‐evolutionary arms race against parasitic infectious diseases

Drug development research, 2022-04, Vol.83 (2), p.219-221

2022

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Telomeric gene deletion and intrachromosomal amplification in antimony‐resistant Leishmania

Molecular microbiology, 2013-04, Vol.88 (1), p.189-202

2013

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Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis

PLoS neglected tropical diseases, 2011-05, Vol.5 (5), p.e1167

2011

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Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

Microbiology spectrum, 2021-10, Vol.9 (2), p.e0101821-e0101821

2021

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Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

Biomedicine & pharmacotherapy, 2021-01, Vol.133, p.111049, Article 111049

2021

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Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

Frontiers in cellular and infection microbiology, 2022-08, Vol.12, p.954144-954144

2022

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Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

Microorganisms (Basel), 2023-04, Vol.11 (4), p.1043

2023

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Improved antileishmanial activity of Dppz through complexation with antimony(III) and bismuth(III): investigation of the role of the metal

Molecules (Basel, Switzerland), 2012-10, Vol.17 (11), p.12622-12635

2012

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Antimony resistance in Leishmania (Viannia) braziliensis clinical isolates from atypical lesions associates with increased ARM56/ARM58 transcripts and reduced drug uptake

Memórias do Instituto Oswaldo Cruz, 2019-01, Vol.114, p.e190111-e190111

2019

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Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

Parasites & vectors, 2021-08, Vol.14 (1), p.438-438, Article 438

2021

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Sex under pressure: stress facilitates Leishmania in vitro hybridization

Trends in parasitology, 2022-04, Vol.38 (4), p.274-276

2022

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Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice

Scientific reports, 2018-08, Vol.8 (1), p.11627-15, Article 11627

2018

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Comparison of diagnostic performance of RT-qPCR, RT-LAMP and IgM/IgG rapid tests for detection of SARS-CoV-2 among healthcare workers in Brazil

Journal of infection and public health, 2023-07, Vol.16 (7), p.1081-1088

2023

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Validation of a colorimetric LAMP to detect Loxosceles experimental envenomation

Toxicon (Oxford), 2022-09, Vol.216, p.50-56

2022

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The mutation G133D on Leishmania guyanensis AQP1 is highly destabilizing as revealed by molecular modeling and hypo-osmotic shock assay

Biochimica et biophysica acta. Biomembranes, 2021-10, Vol.1863 (10), p.183682-183682, Article 183682

2021

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Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania ( Viannia ) Subgenus

Frontiers in cell and developmental biology, 2017-01, Vol.5, p.24-24

2017

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Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions

Biomedicine & pharmacotherapy, 2018-12, Vol.108, p.1170-1180

2018

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Drug resistance analysis by next generation sequencing in Leishmania

International journal for parasitology -- drugs and drug resistance, 2015-04, Vol.5 (1), p.26-35

2015

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Molecular detection of omicron SARS-CoV-2 variant is achieved by RT-LAMP despite genomic mutations

Memórias do Instituto Oswaldo Cruz, 2022-01, Vol.117, p.e220050-e220050

2022

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Susceptibility of Leishmania to novel pentavalent organometallics: Investigating impact on DNA and membrane integrity in antimony(III)‐sensitive and ‐resistant strains

Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery

Leishmania amazonensis from distinct clinical forms/hosts has polymorphisms in Lipophosphoglycans, displays variations in immunomodulatory properties and, susceptibility to antileishmanial drugs

Anticancer and antileishmanial in vitro activity of gold(I) complexes with 1,3,4‐oxadiazole‐2(3H)‐thione ligands derived from δ‐D‐gluconolactone

Recent research brings hope for reshaping the co‐evolutionary arms race against parasitic infectious diseases

Telomeric gene deletion and intrachromosomal amplification in antimony‐resistant Leishmania

Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis

Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing

Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

Exploring direct and indirect targets of current antileishmanial drugs using a novel thermal proteomics profiling approach

Optimization and Clinical Validation of Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification, a Fast, Highly Sensitive and Specific COVID-19 Molecular Diagnostic Tool That Is Robust to Detect SARS-CoV-2 Variants of Concern

Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania

Improved antileishmanial activity of Dppz through complexation with antimony(III) and bismuth(III): investigation of the role of the metal

Antimony resistance in Leishmania (Viannia) braziliensis clinical isolates from atypical lesions associates with increased ARM56/ARM58 transcripts and reduced drug uptake

Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

Sex under pressure: stress facilitates Leishmania in vitro hybridization

Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice

Molecular characterization of a new SARS-CoV-2 recombinant cluster XAG identified in Brazil

Comparison of diagnostic performance of RT-qPCR, RT-LAMP and IgM/IgG rapid tests for detection of SARS-CoV-2 among healthcare workers in Brazil

Validation of a colorimetric LAMP to detect Loxosceles experimental envenomation

The mutation G133D on Leishmania guyanensis AQP1 is highly destabilizing as revealed by molecular modeling and hypo-osmotic shock assay

Biophysical and Pharmacological Characterization of Energy-Dependent Efflux of Sb in Laboratory-Selected Resistant Strains of Leishmania ( Viannia ) Subgenus

Intraspecies susceptibility of Leishmania (Viannia) braziliensis to antileishmanial drugs: Antimony resistance in human isolates from atypical lesions

Drug resistance analysis by next generation sequencing in Leishmania

Molecular detection of omicron SARS-CoV-2 variant is achieved by RT-LAMP despite genomic mutations

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