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Higher-order G-quadruplexes in promoters are untapped drug targets

Frontiers in chemistry, 2023-06, Vol.11, p.1211512-1211512

Monsen, Robert C

2023

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The hTERT core promoter forms three parallel G-quadruplexes

Nucleic acids research, 2020-06, Vol.48 (10), p.5720-5734

2020

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Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

PloS one, 2022-06, Vol.17 (6), p.e0270165-e0270165

2022

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POT1 stability and binding measured by fluorescence thermal shift assays

PloS one, 2021-03, Vol.16 (3), p.e0245675

2021

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Outcome after VAC® Therapy for Infected Bypass Grafts in the Lower Limb

European journal of vascular and endovascular surgery, 2012-09, Vol.44 (3), p.294-299

2012

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G‑quadruplex DNA: A Longer Story

Accounts of chemical research, 2022-11, Vol.55 (22), p.3242-3252

2022

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G-quadruplex virtual drug screening: A review

Biochimie, 2018-09, Vol.152, p.134-148

2018

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A randomised study of NPWT closure versus alginate dressings in peri-vascular groin infections: quality of life, pain and cost

Journal of wound care, 2015-06, Vol.24 (6), p.252, 254-260

2015

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Predictors for Outcome after Vacuum Assisted Closure Therapy of Peri-vascular Surgical Site Infections in the Groin

European journal of vascular and endovascular surgery, 2008-07, Vol.36 (1), p.84-89

2008

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The solution structures of higher-order human telomere G-quadruplex multimers

Nucleic acids research, 2021-02, Vol.49 (3), p.1749-1768

2021

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Outcome after VAC® Therapy for Infected Bypass Grafts in the Lower Limb

Journal of vascular surgery, 2012-09, Vol.56 (3), p.879-879

2012

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Strategy for modeling higher-order G-quadruplex structures recalcitrant to NMR determination

Methods (San Diego, Calif.), 2024-10, Vol.230, p.9-20

2024

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Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences

Nucleic acids research, 2022-04, Vol.50 (7), p.4127-4147

2022

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Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM

Nucleic acids research, 2023-02, Vol.51 (4), p.1943-1959

2023

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Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.2035, p.87

2019

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Angiographic progression of coronary artery disease and the development of myocardial infarction

Journal of the American College of Cardiology, 1988-07, Vol.12 (1), p.56-62

1988

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Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

PloS one, 2022-01, Vol.17 (6), p.e0270165

2022

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Structural characterization and targeting of higher-order promoter G-quadruplexes

Acta crystallographica. Section A, Foundations and advances, 2023-07, Vol.79 (a1), p.a216-a216

2023

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Angiographic demonstration of a common link between unstable angina pectoris and non-Q wave acute myocardial infarction

The American journal of cardiology, 1988-02, Vol.61 (4), p.244-247

1988

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Adjunctive thrombolytic therapy for angioplasty in ischemic rest angina: Results of a double-blind randomized pilot study

Journal of the American College of Cardiology, 1992-11, Vol.20 (5), p.1197-1204

1992

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Long-term clinical outcome of rescue balloon angioplasty compared with rescue stenting after failed thrombolysis

Heart disease (Hagerstown, Md.), 2001-07, Vol.3 (4), p.217-220

2001

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Angiographic patterns of balloon inflation during percutaneous transluminal coronary angioplasty: Role of pressure-diameter curves in studying distensibility and elasticity of the stenotic lesion and the mechanism of dilation

Journal of the American College of Cardiology, 1990-09, Vol.16 (3), p.569-575

1990

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The effects of off-normal hours, age, and gender for coronary angioplasty on hospital mortality in patients undergoing coronary angioplasty for acute myocardial infarction

The American journal of cardiology, 2004-03, Vol.93 (6), p.763-764

2004

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Comparison of frequency of left ventricular thrombi in patients with anterior wall versus non–anterior wall acute myocardial infarction treated with antithrombotic and antiplatelet therapy with or without coronary revascularization

The American journal of cardiology, 2004-06, Vol.93 (12), p.1529-1530

2004

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Adjunctive thrombolytic therapy during angioplasty for ischemic rest angina. Results of the TAUSA Trial. TAUSA Investigators. Thrombolysis and Angioplasty in Unstable Angina trial

Circulation (New York, N.Y.), 1994-07, Vol.90 (1), p.69-77

1994

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Higher-order G-quadruplexes in promoters are untapped drug targets

The hTERT core promoter forms three parallel G-quadruplexes

Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

POT1 stability and binding measured by fluorescence thermal shift assays

Outcome after VAC® Therapy for Infected Bypass Grafts in the Lower Limb

G‑quadruplex DNA: A Longer Story

G-quadruplex virtual drug screening: A review

A randomised study of NPWT closure versus alginate dressings in peri-vascular groin infections: quality of life, pain and cost

Predictors for Outcome after Vacuum Assisted Closure Therapy of Peri-vascular Surgical Site Infections in the Groin

The solution structures of higher-order human telomere G-quadruplex multimers

Outcome after VAC® Therapy for Infected Bypass Grafts in the Lower Limb

Strategy for modeling higher-order G-quadruplex structures recalcitrant to NMR determination

Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences

Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM

Putting a New Spin of G-Quadruplex Structure and Binding by Analytical Ultracentrifugation

Angiographic progression of coronary artery disease and the development of myocardial infarction

Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

Structural characterization and targeting of higher-order promoter G-quadruplexes

Angiographic demonstration of a common link between unstable angina pectoris and non-Q wave acute myocardial infarction

Adjunctive thrombolytic therapy for angioplasty in ischemic rest angina: Results of a double-blind randomized pilot study

Long-term clinical outcome of rescue balloon angioplasty compared with rescue stenting after failed thrombolysis

Angiographic patterns of balloon inflation during percutaneous transluminal coronary angioplasty: Role of pressure-diameter curves in studying distensibility and elasticity of the stenotic lesion and the mechanism of dilation

The effects of off-normal hours, age, and gender for coronary angioplasty on hospital mortality in patients undergoing coronary angioplasty for acute myocardial infarction

Comparison of frequency of left ventricular thrombi in patients with anterior wall versus non–anterior wall acute myocardial infarction treated with antithrombotic and antiplatelet therapy with or without coronary revascularization

Adjunctive thrombolytic therapy during angioplasty for ischemic rest angina. Results of the TAUSA Trial. TAUSA Investigators. Thrombolysis and Angioplasty in Unstable Angina trial

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