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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

PloS one, 2015-05, Vol.10 (5), p.e0126350

2015

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Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3865-3870

2014

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Efflux-Mediated Antifungal Drug Resistance

Clinical Microbiology Reviews, 2009-04, Vol.22 (2), p.291-321

2009

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Outwitting Multidrug Resistance to Antifungals

Science (American Association for the Advancement of Science), 2008-07, Vol.321 (5887), p.367-369

2008

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Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

PloS one, 2016-12, Vol.11 (12), p.e0167485-e0167485

2016

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The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida albicans and Candida glabrata Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2012-03, Vol.56 (3), p.1508-1515

2012

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Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target

Journal of fungi (Basel), 2022-11, Vol.8 (12), p.1256

2022

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Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Journal of fungi (Basel), 2021-01, Vol.7 (2), p.67

2021

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Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery

Journal of fungi (Basel), 2023-01, Vol.9 (2), p.168

2023

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ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates

Antimicrobial Agents and Chemotherapy, 2008-11, Vol.52 (11), p.3851-3862

2008

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[Fe₂L₃]⁴⁺ cylinders derived from bis(bidentate) 2-pyridyl-1,2,3-triazole "click" ligands: synthesis, structures and exploration of biological activity

Molecules (Basel, Switzerland), 2013-05, Vol.18 (6), p.6383-6407

2013

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Pantoea peritonitis in peritoneal dialysis: a report of two cases and literature review

Renal replacement therapy, 2024-09, Vol.10 (1), p.55-7, Article 55

2024

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Protein content of molar–incisor hypomineralisation enamel

Journal of dentistry, 2010-07, Vol.38 (7), p.591-596

2010

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Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p

Analytical biochemistry, 2009-11, Vol.394 (1), p.87-91

2009

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Fungal PDR transporters: Phylogeny, topology, motifs and function

Fungal genetics and biology, 2010-02, Vol.47 (2), p.127-142

2010

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Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Journal of fungi (Basel), 2021-11, Vol.7 (12), p.1011

2021

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Characterization of Three Classes of Membrane Proteins Involved in Fungal Azole Resistance by Functional Hyperexpression in Saccharomyces cerevisiae

Eukaryotic Cell, 2007-07, Vol.6 (7), p.1150-1165

2007

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Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

Journal of fungi (Basel), 2021-01, Vol.7 (2), p.68

2021

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Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

Journal of fungi (Basel), 2022-01, Vol.8 (1), p.69

2022

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Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Journal of fungi (Basel), 2023-06, Vol.9 (6), p.663

2023

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Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d-octapeptide derivative inhibitor

Molecular microbiology, 2012-08, Vol.85 (4), p.747-767

2012

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Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Biochimica et biophysica acta. Proteins and proteomics, 2020-03, Vol.1868 (3), p.140206, Article 140206

2020

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Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Journal of fungi (Basel), 2021-10, Vol.7 (11), p.897

2021

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Highlighting membrane protein structure and function: A celebration of the Protein Data Bank

The Journal of biological chemistry, 2021-01, Vol.296, p.100557-100557, Article 100557

2021

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Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric

Scientific reports, 2016-06, Vol.6 (1), p.27132, Article 27132

2016

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Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

Efflux-Mediated Antifungal Drug Resistance

Outwitting Multidrug Resistance to Antifungals

Structural and Functional Elucidation of Yeast Lanosterol 14α-Demethylase in Complex with Agrochemical Antifungals

The Monoamine Oxidase A Inhibitor Clorgyline Is a Broad-Spectrum Inhibitor of Fungal ABC and MFS Transporter Efflux Pump Activities Which Reverses the Azole Resistance of Candida albicans and Candida glabrata Clinical Isolates

Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target

Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases

Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery

ABC Transporter Cdr1p Contributes More than Cdr2p Does to Fluconazole Efflux in Fluconazole-Resistant Candida albicans Clinical Isolates

[Fe₂L₃]⁴⁺ cylinders derived from bis(bidentate) 2-pyridyl-1,2,3-triazole "click" ligands: synthesis, structures and exploration of biological activity

Pantoea peritonitis in peritoneal dialysis: a report of two cases and literature review

Protein content of molar–incisor hypomineralisation enamel

Identification of Nile red as a fluorescent substrate of the Candida albicans ATP-binding cassette transporters Cdr1p and Cdr2p and the major facilitator superfamily transporter Mdr1p

Fungal PDR transporters: Phylogeny, topology, motifs and function

Correction: Monk, B.C.; Keniya, M.V. Roles for Structural Biology in the Discovery of Drugs and Agrochemicals Targeting Sterol 14α-Demethylases. J. Fungi 2021, 7 , 67

Characterization of Three Classes of Membrane Proteins Involved in Fungal Azole Resistance by Functional Hyperexpression in Saccharomyces cerevisiae

Directed Mutational Strategies Reveal Drug Binding and Transport by the MDR Transporters of Candida albicans

Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host

Clorgyline Analogs Synergize with Azoles against Drug Efflux in Candida auris

Specific interactions between the Candida albicans ABC transporter Cdr1p ectodomain and a d-octapeptide derivative inhibitor

Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design

Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate

Highlighting membrane protein structure and function: A celebration of the Protein Data Bank

Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric

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