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Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Journal of medicinal chemistry, 1989-03, Vol.32 (3), p.715-720

1989

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The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development

The Journal of immunology (1950), 1998-07, Vol.161 (1), p.183-191

1998

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Peptide Binding Identifies an ERα Conformation That Generates Selective Activity in Multiple In Vitro Assays

SLAS discovery, 2005-09, Vol.10 (6), p.590-598

2005

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cis-4-Carboxy-6-(mercaptomethyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one, a potent inhibitor of mammalian dihydroorotase

Journal of medicinal chemistry, 1988-07, Vol.31 (7), p.1355-1359

1988

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Transient activation of topoisomerase I in leukotriene D4 signal transduction in human cells

Biochemical journal, 1990-01, Vol.265 (1), p.101-107

1990

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Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells

Cancer research (Chicago, Ill.), 1987-04, Vol.47 (7), p.1793-1798

1987

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Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds

Chemical research in toxicology, 1988-09, Vol.1 (5), p.258-268

1988

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Cellular pharmacology of mu-[1,2-bis(diphenylphosphino)ethane]bis[(1-thio-beta-D-gluco pyranosato-S)gold(I)]: a novel antitumor agent

Anti-cancer drug design, 1986-11, Vol.1 (3), p.223

1986

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Evidence for the participation of topoisomerases I and II in cadmium-induced metallothionein expression in Chinese hamster ovary cells

Anti-cancer drug design, 1989-08, Vol.4 (2), p.107

1989

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Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs

Journal of medicinal chemistry, 1989-02, Vol.32 (2), p.409-417

1989

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In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

Cancer research (Chicago, Ill.), 1989-05, Vol.49 (10), p.2578-2583

1989

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In vivo antitumor activity and in vitro cytotoxic properties of bis[1,2-bis(diphenylphosphino)ethane]gold(I) chloride

Cancer research (Chicago, Ill.), 1986-11, Vol.46 (11), p.5486-5493

1986

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The translation products of moloney murine sarcoma virus-124 RNA

Virology (New York, N.Y.), 1980-08, Vol.105 (1), p.60-70

1980

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APPLICATION OF A TISSUE CULTURE MICROTITER TEST FOR THE DETECTION OF CYTOTOXIC AGENTS FROM NATURAL PRODUCTS

The Journal of Antibiotics, 1985, Vol.38(6), pp.758-766

1985

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In vivo and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

Cancer research (Chicago, Ill.), 1989-01, Vol.49 (10), p.2578-2583

1989

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Leukotriene D4 receptor-mediated phosphoinositol hydrolysis and calcium mobilization in rat basophilic leukemic cells

The Journal of pharmacology and experimental therapeutics, 1988-11, Vol.247 (2), p.803

1988

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Synthesis and antineoplastic activity of alanyl-2-glycyl peptide derivatives of nocodazole

European journal of medicinal chemistry, 1989, Vol.24 (4), p.363-370

1989

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TRANSLATION PRODUCTS OF THE 124 STRAIN OF MOLONEY MURINE SARCOMA VIRUS (Mo-MuSV): CHARACTERIZATION OF A 23,000 DALTON CANDIDATE ‘src’ GENE PRODUCT

Animal Virus Genetics, 1980, p.643-655

1980

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Sex differences in sleep: impact of biological sex and sex steroids

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2016-02, Vol.371 (1688), p.20150110

2016

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Electrical Probes of the Non-Abelian Spin Liquid in Kitaev Materials

Physical review. X, 2020-07, Vol.10 (3), p.031014, Article 031014

2020

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Acute Kynurenine Challenge Disrupts Sleep–Wake Architecture and Impairs Contextual Memory in Adult Rats

Sleep (New York, N.Y.), 2017-11, Vol.40 (11)

2017

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DNA metabarcoding of insects and allies: an evaluation of primers and pipelines

Bulletin of entomological research, 2015-12, Vol.105 (6), p.717-727

2015

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A shift from drought to extreme rainfall drives a stable landslide to catastrophic failure

Scientific reports, 2019-02, Vol.9 (1), p.1569-1569, Article 1569

2019

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Quantized response and topology of magnetic insulators with inversion symmetry

Physical review. B, Condensed matter and materials physics, 2012-04, Vol.85 (16), Article 165120

2012

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Probing the lithospheric rheology across the eastern margin of the Tibetan Plateau

Earth and planetary science letters, 2014-06, Vol.396, p.88-96

2014

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Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

The cytoplasmic domain of CD8 beta regulates Lck kinase activation and CD8 T cell development

Peptide Binding Identifies an ERα Conformation That Generates Selective Activity in Multiple In Vitro Assays

cis-4-Carboxy-6-(mercaptomethyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one, a potent inhibitor of mammalian dihydroorotase

Transient activation of topoisomerase I in leukotriene D4 signal transduction in human cells

Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells

Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds

Cellular pharmacology of mu-[1,2-bis(diphenylphosphino)ethane]bis[(1-thio-beta-D-gluco pyranosato-S)gold(I)]: a novel antitumor agent

Evidence for the participation of topoisomerases I and II in cadmium-induced metallothionein expression in Chinese hamster ovary cells

Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs

In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

In vivo antitumor activity and in vitro cytotoxic properties of bis[1,2-bis(diphenylphosphino)ethane]gold(I) chloride

The translation products of moloney murine sarcoma virus-124 RNA

APPLICATION OF A TISSUE CULTURE MICROTITER TEST FOR THE DETECTION OF CYTOTOXIC AGENTS FROM NATURAL PRODUCTS

In vivo and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

Leukotriene D4 receptor-mediated phosphoinositol hydrolysis and calcium mobilization in rat basophilic leukemic cells

Synthesis and antineoplastic activity of alanyl-2-glycyl peptide derivatives of nocodazole

TRANSLATION PRODUCTS OF THE 124 STRAIN OF MOLONEY MURINE SARCOMA VIRUS (Mo-MuSV): CHARACTERIZATION OF A 23,000 DALTON CANDIDATE ‘src’ GENE PRODUCT

Sex differences in sleep: impact of biological sex and sex steroids

Electrical Probes of the Non-Abelian Spin Liquid in Kitaev Materials

Acute Kynurenine Challenge Disrupts Sleep–Wake Architecture and Impairs Contextual Memory in Adult Rats

DNA metabarcoding of insects and allies: an evaluation of primers and pipelines

A shift from drought to extreme rainfall drives a stable landslide to catastrophic failure

Quantized response and topology of magnetic insulators with inversion symmetry

Probing the lithospheric rheology across the eastern margin of the Tibetan Plateau

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