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Bayesian modeling and simulation to inform rare disease drug development early decision-making: Application to Duchenne muscular dystrophy

PloS one, 2022-04, Vol.17 (4), p.e0247286-e0247286

2022

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Integration of modeling and simulation into hospital-based decision support systems guiding pediatric pharmacotherapy

BMC medical informatics and decision making, 2008-01, Vol.8 (1), p.6-6, Article 6

2008

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Population Pharmacokinetic-Pharmacodynamic Modeling of Variable Wear Times for a Dextroamphetamine Transdermal System

CNS spectrums, 2023-04, Vol.28 (2), p.246-246

2023

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Latent process model of the 6-minute walk test in Duchenne muscular dystrophy: A Bayesian approach to quantifying rare disease progression

Journal of pharmacokinetics and pharmacodynamics, 2020-02, Vol.47 (1), p.91-104

2020

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Delayed Small Bowel Transit in Children With Cystic Fibrosis and Pancreatic Insufficiency

Journal of pediatric gastroenterology and nutrition, 2013-07, Vol.57 (1), p.81-84

2013

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Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults

Cancer chemotherapy and pharmacology, 2009, Vol.63 (2), p.229-238

2009

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Diagnosing malabsorption with systemic lipid profiling: pharmacokinetics of pentadecanoic acid and triheptadecanoic acid following oral administration in healthy subjects and subjects with cystic fibrosis

International journal of clinical pharmacology and therapeutics, 2013-04, Vol.51 (4), p.263-273

2013

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Population pharmacokinetics of ketorolac in neonates and young infants

American journal of therapeutics, 2009-03, Vol.16 (2), p.143-146

2009

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Plasma topiramate concentrations resulting from doses associated with neuroprotection against white matter injury and stroke in two strains of rat pups

Pediatric research, 2013-03, Vol.73 (3), p.317-324

2013

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Safety, Tolerability, Pharmacokinetics, and Time Course of Pharmacologic Response of the Active Metabolite of Roxifiban, XV459, a Glycoprotein IIb/IIIa Antagonist, following Oral Administration in Healthy Volunteers

Journal of clinical pharmacology, 2002-07, Vol.42 (7), p.738-753

2002

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Population pharmacokinetics of milrinone in neonates with hypoplastic left heart syndrome undergoing stage I reconstruction

Anesthesia and analgesia, 2006-04, Vol.102 (4), p.1062-1069

2006

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Population Pharmacokinetic Investigation of Actinomycin-D in Children and Young Adults

Journal of clinical pharmacology, 2008-01, Vol.48 (1), p.35-42

2008

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Population pharmacokinetics of intravenous ondansetron in oncology and surgical patients aged 1−48 months

European journal of clinical pharmacology, 2010, Vol.66 (1), p.77-86

2010

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Model-based drug development applied to oncology

Expert opinion on drug discovery, 2007-02, Vol.2 (2), p.185-209

2007

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An Informatics Approach to Assess Pediatric Pharmacotherapy: Design and Implementation of a Hospital Drug Utilization System

Journal of clinical pharmacology, 2007-09, Vol.47 (9), p.1172-1180

2007

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3.1 Population Pharmacokinetic-Pharmacodynamic Modeling of Variable Wear Times for a Dextroamphetamine Transdermal System

Journal of the American Academy of Child and Adolescent Psychiatry, 2022-10, Vol.61 (10), p.S228-S228

2022

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Drug Utilization in the Pediatric Intensive Care Unit: Monitoring Prescribing Trends and Establishing Prioritization of Pharmacotherapeutic Evaluation of Critically Ill Children

Journal of clinical pharmacology, 2005-11, Vol.45 (11), p.1305-1312

2005

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Latent process model of the 6-minute walk test in Duchenne muscular dystrophy

Journal of pharmacokinetics and pharmacodynamics, 2020-02, Vol.47 (1), p.91-104

2020

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Immunogenicity of cipaglucosidase alfa/miglustat versus alglucosidase alfa/placebo in late-onset Pompe disease (LOPD): A phase III, randomized study (PROPEL)

Molecular genetics and metabolism, 2022-02, Vol.135 (2), p.S30-S30

2022

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Population pharmacokinetics of the selective serotonin 5-HT1A receptor partial agonist piclozotan

American journal of therapeutics, 2009-03, Vol.16 (2), p.106-115

2009

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Safety, Tolerability, Pharmacokinetics, and Time Course of Pharmacologic Response of the Active Metabolite of Roxifiban, XV459, a Glycoprotein IIb/IIIa Antagonist, following Oral Administration in Healthy Volunteers

Journal of clinical pharmacology, 2002-07, Vol.42 (7), p.738-753

2002

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Pedlatric Knowledgebase (PKB) – A Hospital-based, Decision Support System to Guide Pharmacotherapy: 41

Journal of clinical pharmacology, 2008-09, Vol.48 (9), p.1108-1108

2008

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Population Pharmacokinetics of Palivizumab, a Humanized Anti-Respiratory Syncytial Virus Monoclonal Antibody, in Adults and Children

Antimicrobial Agents and Chemotherapy, 2012-09, Vol.56 (9), p.4927-4936

2012

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Population pharmacokinetics of total and unbound valemetostat and platelet dynamics in healthy volunteers and patients with non‐Hodgkin lymphoma

CPT: pharmacometrics and systems pharmacology, 2024-10, Vol.13 (10), p.1641-1654

2024

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Bayesian estimation in NONMEM

CPT: pharmacometrics and systems pharmacology, 2024-02, Vol.13 (2), p.192-207

2024

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Bayesian modeling and simulation to inform rare disease drug development early decision-making: Application to Duchenne muscular dystrophy

Integration of modeling and simulation into hospital-based decision support systems guiding pediatric pharmacotherapy

Population Pharmacokinetic-Pharmacodynamic Modeling of Variable Wear Times for a Dextroamphetamine Transdermal System

Latent process model of the 6-minute walk test in Duchenne muscular dystrophy: A Bayesian approach to quantifying rare disease progression

Delayed Small Bowel Transit in Children With Cystic Fibrosis and Pancreatic Insufficiency

Population pharmacokinetics of imatinib mesylate and its metabolite in children and young adults

Diagnosing malabsorption with systemic lipid profiling: pharmacokinetics of pentadecanoic acid and triheptadecanoic acid following oral administration in healthy subjects and subjects with cystic fibrosis

Population pharmacokinetics of ketorolac in neonates and young infants

Plasma topiramate concentrations resulting from doses associated with neuroprotection against white matter injury and stroke in two strains of rat pups

Safety, Tolerability, Pharmacokinetics, and Time Course of Pharmacologic Response of the Active Metabolite of Roxifiban, XV459, a Glycoprotein IIb/IIIa Antagonist, following Oral Administration in Healthy Volunteers

Population pharmacokinetics of milrinone in neonates with hypoplastic left heart syndrome undergoing stage I reconstruction

Population Pharmacokinetic Investigation of Actinomycin-D in Children and Young Adults

Population pharmacokinetics of intravenous ondansetron in oncology and surgical patients aged 1−48 months

Model-based drug development applied to oncology

An Informatics Approach to Assess Pediatric Pharmacotherapy: Design and Implementation of a Hospital Drug Utilization System

3.1 Population Pharmacokinetic-Pharmacodynamic Modeling of Variable Wear Times for a Dextroamphetamine Transdermal System

Drug Utilization in the Pediatric Intensive Care Unit: Monitoring Prescribing Trends and Establishing Prioritization of Pharmacotherapeutic Evaluation of Critically Ill Children

Latent process model of the 6-minute walk test in Duchenne muscular dystrophy

Immunogenicity of cipaglucosidase alfa/miglustat versus alglucosidase alfa/placebo in late-onset Pompe disease (LOPD): A phase III, randomized study (PROPEL)

Population pharmacokinetics of the selective serotonin 5-HT1A receptor partial agonist piclozotan

Safety, Tolerability, Pharmacokinetics, and Time Course of Pharmacologic Response of the Active Metabolite of Roxifiban, XV459, a Glycoprotein IIb/IIIa Antagonist, following Oral Administration in Healthy Volunteers

Pedlatric Knowledgebase (PKB) – A Hospital-based, Decision Support System to Guide Pharmacotherapy: 41

Population Pharmacokinetics of Palivizumab, a Humanized Anti-Respiratory Syncytial Virus Monoclonal Antibody, in Adults and Children

Population pharmacokinetics of total and unbound valemetostat and platelet dynamics in healthy volunteers and patients with non‐Hodgkin lymphoma

Bayesian estimation in NONMEM

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