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Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability

Clinical pharmacokinetics, 2021-08, Vol.60 (8), p.971-984

2021

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A single post‐exposure oxime RS194B treatment rapidly reactivates acetylcholinesterase and reverses acute symptoms in macaques exposed to diethylphosphorothioate parathion and chlorpyrifos insecticides

Journal of neurochemistry, 2024-04, Vol.168 (4), p.370-380

2024

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Non-invasive skin sampling detects systemically administered drugs in humans

PloS one, 2022-07, Vol.17 (7), p.e0271794-e0271794

2022

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The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

Clinical pharmacology and therapeutics, 2020-07, Vol.108 (1), p.40-53

2020

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Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis

Cell chemical biology, 2023-09, Vol.30 (9), p.1090-1103.e7

2023

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Brief Report: Pharmacokinetics of Bictegravir and Tenofovir in Combination With Darunavir/Cobicistat in Treatment-Experienced Persons With HIV

Journal of acquired immune deficiency syndromes (1999), 2021-12, Vol.88 (4), p.389

2021

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Clinical lactation studies and the role of pharmacokinetic modeling and simulation in predicting drug exposures in breastfed infants

Journal of pharmacokinetics and pharmacodynamics, 2020-08, Vol.47 (4), p.295-304

2020

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Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial

The Lancet (British edition), 2021-04, Vol.397 (10281), p.1276-1292

2021

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Consensus Recommendations for Systematic Evaluation of Drug–Drug Interaction Evidence for Clinical Decision Support

Drug safety, 2015-02, Vol.38 (2), p.197-206

2015

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Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats

Psychopharmacology, 2020-05, Vol.237 (5), p.1545-1555

2020

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Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1609-1625

2019

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Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir

Journal of clinical pharmacology, 2020-02, Vol.60 (2), p.240-255

2020

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Elvitegravir/cobicistat pharmacokinetics in pregnant and postpartum women with HIV

AIDS (London), 2018-11, Vol.32 (17), p.2507-2516

2018

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Translating Clinical Pharmacology Data in Pregnancy to Evidence‐Based Guideline Recommendations: Perspectives From the HIV Field

Journal of clinical pharmacology, 2023-06, Vol.63 (S1), p.S188-S196

2023

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Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication

Expert opinion on drug metabolism & toxicology, 2018-06, Vol.14 (6), p.561-570

2018

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Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation

Clinical journal of the American Society of Nephrology, 2019-04, Vol.14 (4), p.540-548

2019

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Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin

Journal of the American Chemical Society, 2019-07, Vol.141 (30), p.11765-11769

2019

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Concentrations of remdesivir and GS-441524 in human milk from lactating individuals diagnosed with COVID-19

Pediatric research, 2024-02, Vol.96 (2), p.269-272

2024

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Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum

Journal of acquired immune deficiency syndromes (1999), 2023-12, Vol.94 (4), p.332

2023

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Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors

Journal of the American Chemical Society, 2018-09, Vol.140 (36), p.11424-11437

2018

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In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3

Nutrients, 2024-07, Vol.16 (14), p.2242

2024

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Pediatric and Adult Placebo Response Rates in Placebo‐Controlled Clinical Trials Submitted to the US Food and Drug Administration 2012–2020

Journal of clinical pharmacology, 2022-08, Vol.62 (8), p.970-982

2022

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Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV

Clinical pharmacokinetics, 2020-10, Vol.59 (10), p.1185-1194

2020

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Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning

Pharmaceutics, 2024-05, Vol.16 (5), p.592

2024

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Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques

Toxicology letters, 2018-09, Vol.293, p.229-234

2018

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Contribution of the Gut Microbiome to Drug Disposition, Pharmacokinetic and Pharmacodynamic Variability

A single post‐exposure oxime RS194B treatment rapidly reactivates acetylcholinesterase and reverses acute symptoms in macaques exposed to diethylphosphorothioate parathion and chlorpyrifos insecticides

Non-invasive skin sampling detects systemically administered drugs in humans

The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis

Brief Report: Pharmacokinetics of Bictegravir and Tenofovir in Combination With Darunavir/Cobicistat in Treatment-Experienced Persons With HIV

Clinical lactation studies and the role of pharmacokinetic modeling and simulation in predicting drug exposures in breastfed infants

Consensus Recommendations for Systematic Evaluation of Drug–Drug Interaction Evidence for Clinical Decision Support

Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats

Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir

Elvitegravir/cobicistat pharmacokinetics in pregnant and postpartum women with HIV

Translating Clinical Pharmacology Data in Pregnancy to Evidence‐Based Guideline Recommendations: Perspectives From the HIV Field

Developmental regulation of kidney and liver solute carrier and ATP-binding cassette drug transporters and drug metabolizing enzymes: the role of remote organ communication

Dynamics of Organic Anion Transporter-Mediated Tubular Secretion during Postnatal Human Kidney Development and Maturation

Antitumor Activity of 1,18-Octadecanedioic Acid-Paclitaxel Complexed with Human Serum Albumin

Concentrations of remdesivir and GS-441524 in human milk from lactating individuals diagnosed with COVID-19

Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum

Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors

In Vivo Regulation of Small Molecule Natural Products, Antioxidants, and Nutrients by OAT1 and OAT3

Pediatric and Adult Placebo Response Rates in Placebo‐Controlled Clinical Trials Submitted to the US Food and Drug Administration 2012–2020

Innovative Approaches for Pharmacology Studies in Pregnant and Lactating Women: A Viewpoint and Lessons from HIV

Distinguishing Molecular Properties of OAT, OATP, and MRP Drug Substrates by Machine Learning

Post-exposure treatment with the oxime RS194B rapidly reactivates and reverses advanced symptoms of lethal inhaled paraoxon in macaques

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