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Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?

Molecular medicine (Cambridge, Mass.), 2020-08, Vol.26 (1), p.1-80, Article 80

2020

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Galanin 2 Receptor: A Novel Target for a Subset of Pancreatic Ductal Adenocarcinoma

International journal of molecular sciences, 2023-06, Vol.24 (12), p.10193

2023

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Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

Nature communications, 2017-11, Vol.8 (1), p.1500-10, Article 1500

2017

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Genetically Encoded Libraries of Constrained Peptides

Chembiochem : a European journal of chemical biology, 2019-07, Vol.20 (14), p.1754-1758

2019

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Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models

Peptides (New York, N.Y. : 1980), 2019-02, Vol.112, p.78-84

2019

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Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist

The Journal of pathology, 2011-12, Vol.225 (4), p.618-627

2011

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Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer

European journal of pharmacology, 2024-09, Vol.978, p.176772, Article 176772

Moll, Gert N.

2024

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High-Throughput Screening for Substrate Specificity-Adapted Mutants of the Nisin Dehydratase NisB

ACS synthetic biology, 2020-06, Vol.9 (6), p.1468-1478

2020

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Requirements of the Engineered Leader Peptide of Nisin for Inducing Modification, Export, and Cleavage

Applied and Environmental Microbiology, 2011-01, Vol.77 (2), p.604-611

2011

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Mechanistic aspects of lanthipeptide leaders

Current protein & peptide science, 2013-03, Vol.14 (2), p.85-96

2013

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Discovery, Production and Modification of Five Novel Lantibiotics Using the Promiscuous Nisin Modification Machinery

ACS synthetic biology, 2016-10, Vol.5 (10), p.1146-1154

2016

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Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog

The Journal of pharmacology and experimental therapeutics, 2009-03, Vol.328 (3), p.849-854

2009

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Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis

Science (American Association for the Advancement of Science), 2006-03, Vol.311 (5766), p.1464-1467

2006

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Determining sites of interaction between prenisin and its modification enzymes NisB and NisC

Molecular microbiology, 2011-11, Vol.82 (3), p.706-718

2011

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Dissection and Modulation of the Four Distinct Activities of Nisin by Mutagenesis of Rings A and B and by C-Terminal Truncation

Applied and Environmental Microbiology, 2007-09, Vol.73 (18), p.5809-5816

2007

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Mutagenesis of nisin’s leader peptide proline strongly modulates export of precursor nisin

Antonie van Leeuwenhoek, 2017-03, Vol.110 (3), p.321-330

2017

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Substrate Recognition and Specificity of the NisB Protein, the Lantibiotic Dehydratase Involved in Nisin Biosynthesis

The Journal of biological chemistry, 2011-09, Vol.286 (35), p.30552-30560

2011

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Production of a Class II Two-Component Lantibiotic of Streptococcus pneumoniae Using the Class I Nisin Synthetic Machinery and Leader Sequence

Antimicrobial Agents and Chemotherapy, 2010-04, Vol.54 (4), p.1498-1505

2010

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Bacterial Display and Screening of Posttranslationally Thioether-Stabilized Peptides

Applied and Environmental Microbiology, 2011-10, Vol.77 (19), p.6794-6801

2011

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An Engineered Double Lipid II Binding Motifs-Containing Lantibiotic Displays Potent and Selective Antimicrobial Activity against Enterococcus faecium

Antimicrobial agents and chemotherapy, 2020-05, Vol.64 (6)

2020

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Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides

Antonie van Leeuwenhoek, 2010-05, Vol.97 (4), p.319-333

2010

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AT2 receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung remodelling

Peptides (New York, N.Y. : 1980), 2023-12, Vol.170, p.171106-171106, Article 171106

2023

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Post-translational Modification of Therapeutic Peptides By NisB, the Dehydratase of the Lantibiotic Nisin

Biochemistry (Easton), 2005-09, Vol.44 (38), p.12827-12834

2005

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Evolving views on the first two ligands of the angiotensin II type 2 receptor. From putative antagonists to potential agonists?

European journal of pharmacology, 2023-12, Vol.961, p.176189-176189, Article 176189

2023

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LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study

Peptides (New York, N.Y. : 1980), 2021-02, Vol.136, p.170468, Article 170468

2021

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Does activation of the protective Renin-Angiotensin System have therapeutic potential in COVID-19?

Galanin 2 Receptor: A Novel Target for a Subset of Pancreatic Ductal Adenocarcinoma

Phage display and selection of lanthipeptides on the carboxy-terminus of the gene-3 minor coat protein

Genetically Encoded Libraries of Constrained Peptides

Efficacy of lanthionine-stabilized angiotensin-(1-7) in type I and type II diabetes mouse models

Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist

Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer

High-Throughput Screening for Substrate Specificity-Adapted Mutants of the Nisin Dehydratase NisB

Requirements of the Engineered Leader Peptide of Nisin for Inducing Modification, Export, and Cleavage

Mechanistic aspects of lanthipeptide leaders

Discovery, Production and Modification of Five Novel Lantibiotics Using the Promiscuous Nisin Modification Machinery

Angiotensin-(1-7) with thioether bridge: an angiotensin-converting enzyme-resistant, potent angiotensin-(1-7) analog

Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis

Determining sites of interaction between prenisin and its modification enzymes NisB and NisC

Dissection and Modulation of the Four Distinct Activities of Nisin by Mutagenesis of Rings A and B and by C-Terminal Truncation

Mutagenesis of nisin’s leader peptide proline strongly modulates export of precursor nisin

Substrate Recognition and Specificity of the NisB Protein, the Lantibiotic Dehydratase Involved in Nisin Biosynthesis

Production of a Class II Two-Component Lantibiotic of Streptococcus pneumoniae Using the Class I Nisin Synthetic Machinery and Leader Sequence

Bacterial Display and Screening of Posttranslationally Thioether-Stabilized Peptides

An Engineered Double Lipid II Binding Motifs-Containing Lantibiotic Displays Potent and Selective Antimicrobial Activity against Enterococcus faecium

Microbial engineering of dehydro-amino acids and lanthionines in non-lantibiotic peptides

AT2 receptor agonist LP2 restores respiratory function in a rat model of bleomycin-induced lung remodelling

Post-translational Modification of Therapeutic Peptides By NisB, the Dehydratase of the Lantibiotic Nisin

Evolving views on the first two ligands of the angiotensin II type 2 receptor. From putative antagonists to potential agonists?

LP2, the first lanthipeptide GPCR agonist in a human pharmacokinetics and safety study

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