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Murine Models of Sepsis and Trauma: Can We Bridge the Gap?

ILAR journal, 2017-07, Vol.58 (1), p.90-105

2017

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Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome

Critical care medicine, 2017-02, Vol.45 (2), p.253-262

2017

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Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)

Critical care medicine, 2019-05, Vol.47 (5), p.632-642

2019

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Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Frontiers in immunology, 2018-07, Vol.9, p.1511-1511

2018

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Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Intensive care medicine, 2019-10, Vol.45 (10), p.1360-1371

2019

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Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Critical care (London, England), 2019-11, Vol.23 (1), p.355-355, Article 355

2019

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Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients

The journal of trauma and acute care surgery, 2018-02, Vol.84 (2), p.342-349

2018

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Persistent Inflammation, Immunosuppression and Catabolism Syndrome

Critical care clinics, 2017-04, Vol.33 (2), p.245-258

2017

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Mice are not men

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (4), p.E345-E345

2015

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Unique transcriptomic response to sepsis is observed among patients of different age groups

PloS one, 2017-09, Vol.12 (9), p.e0184159-e0184159

2017

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Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

Frontiers in immunology, 2018-04, Vol.9, p.595-595

2018

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The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients

The journal of trauma and acute care surgery, 2018-08, Vol.85 (2), p.247-255

2018

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Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection

Clinical science (1979), 2023-06, Vol.137 (12), p.963-978

2023

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Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

Critical care (London, England), 2020-05, Vol.24 (1), p.203-203, Article 203

2020

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Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study

Critical care (London, England), 2023-07, Vol.27 (1), p.292-292, Article 292

2023

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HMGB1 as a therapeutic target for sepsis: it's all in the timing

Expert opinion on therapeutic targets, 2014-03, Vol.18 (3), p.243-245

2014

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DAMPs, PAMPs, and the origins of SIRS in bacterial sepsis

Shock (Augusta, Ga.), 2013-01, Vol.39 (1), p.113-114

2013

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Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial

Annals of intensive care, 2023-03, Vol.13 (1), p.17-17, Article 17

2023

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Apoptosis in sepsis: a new target for therapeutic exploration

The FASEB journal, 2001-04, Vol.15 (6), p.879-892

2001

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Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis

Journal of Perinatology, 2009-02, Vol.29 (2), p.79-88

2009

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B cells enhance early innate immune responses during bacterial sepsis

The Journal of experimental medicine, 2011-08, Vol.208 (8), p.1673-1682

2011

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Sepsis syndromes : Understanding the role of innate and acquired immunity

Shock (Augusta, Ga.), 2001-08, Vol.16 (2), p.83-96

2001

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The impact of sarcopenia and acute muscle mass loss on long‐term outcomes in critically ill patients with intra‐abdominal sepsis

Journal of cachexia, sarcopenia and muscle, 2021-10, Vol.12 (5), p.1203-1213

2021

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Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis

Frontiers in immunology, 2021-12, Vol.12, p.792448-792448

2021

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Cytokine signaling-regulation of the immune response in normal and critically ill states

Critical care medicine, 2000-04, Vol.28 (4 Suppl), p.N3-N12

2000

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Murine Models of Sepsis and Trauma: Can We Bridge the Gap?

Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome

Immune Checkpoint Inhibition in Sepsis: A Phase 1b Randomized, Placebo-Controlled, Single Ascending Dose Study of Antiprogrammed Cell Death-Ligand 1 Antibody (BMS-936559)

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Immune checkpoint inhibition in sepsis: a Phase 1b randomized study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of nivolumab

Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients

Persistent Inflammation, Immunosuppression and Catabolism Syndrome

Mice are not men

Unique transcriptomic response to sepsis is observed among patients of different age groups

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients

Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection

Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study

HMGB1 as a therapeutic target for sepsis: it's all in the timing

DAMPs, PAMPs, and the origins of SIRS in bacterial sepsis

Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial

Apoptosis in sepsis: a new target for therapeutic exploration

Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis

B cells enhance early innate immune responses during bacterial sepsis

Sepsis syndromes : Understanding the role of innate and acquired immunity

The impact of sarcopenia and acute muscle mass loss on long‐term outcomes in critically ill patients with intra‐abdominal sepsis

Overlapping but Disparate Inflammatory and Immunosuppressive Responses to SARS-CoV-2 and Bacterial Sepsis: An Immunological Time Course Analysis

Cytokine signaling-regulation of the immune response in normal and critically ill states

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