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Brain Distribution of a Panel of Epidermal Growth Factor Receptor Inhibitors Using Cassette Dosing in Wild-Type and Abcb1/Abcg2 -Deficient Mice

Drug metabolism and disposition, 2019-04, Vol.47 (4), p.393-404

2019

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Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (2), p.238-246

2017

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Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

Journal of Central Nervous System Disease, 2019, Vol.11, p.1179573519840652-1179573519840652

2019

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Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma

Scientific reports, 2020-04, Vol.10 (1), p.6524-6524, Article 6524

2020

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Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer

Clinical & experimental metastasis, 2016-04, Vol.33 (4), p.373-383

2016

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Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

BMC cancer, 2018-12, Vol.18 (1), p.1225-1225, Article 1225

2018

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Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases

Pharmacological research, 2018-06, Vol.132, p.47-68

2018

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A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior

Archives of neuroscience, 2017-04, Vol.4 (2)

2017

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Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer

Pharmaceutical research, 2018-02, Vol.35 (2), p.31-10, Article 31

2018

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Molecular determinants of blood-brain barrier permeation

Therapeutic delivery, 2015-08, Vol.6 (8), p.961-971

2015

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Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor

Drug metabolism and disposition, 2022-03, Vol.50 (3), p.277-286

2022

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Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.343-357

2021

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Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

The Journal of pharmacology and experimental therapeutics, 2019-03, Vol.368 (3), p.446-461

2019

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Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity

The Journal of pharmacology and experimental therapeutics, 2022-01, Vol.380 (1), p.34-46

2022

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Lisdexamfetamine Pharmacokinetic Comparison Between Patients Who Underwent Roux-en-Y Gastric Bypass and Nonsurgical Controls

Obesity surgery, 2021-10, Vol.31 (10), p.4289-4294

2021

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NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

BMC cancer, 2015-10, Vol.15 (1), p.685-685, Article 685

2015

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Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy

Journal of neuroscience methods, 2016-09, Vol.270, p.124-131

2016

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High-dose MTX110 (soluble panobinostat) safely administered into the fourth ventricle in a nonhuman primate model

Journal of neurosurgery. Pediatrics, 2020-08, Vol.26 (2), p.127-135

2020

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P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

Frontiers in pharmacology, 2013-01, Vol.4, p.136-136

2013

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A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier

Cancer prevention research (Philadelphia, Pa.), 2015-01, Vol.8 (1), p.68-76

2015

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Novel treatment strategies for brain tumors and metastases

Pharmaceutical patent analyst, 2014-05, Vol.3 (3), p.279-296

2014

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Abstract 1832: Bioluminescent pharmacokinetics of luciferin in preclinical brain metastases of breast cancer models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1832-1832

2017

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Abstract 4172: Radiation-induced blood-tumor barrier permeability in a preclinical model of lung cancer brain metastasis

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4172-4172

2018

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DDEL-09. HIGH DOSE MTX110 (SOLUBLE PANOBINOSTAT) SAFELY ADMINISTERED INTO THE FOURTH VENTRICLE IN A NON-HUMAN PRIMATE MODEL

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii285-iii285

2020

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Abstract 6276: Brain penetrant MDM2 inhibitor RG7388 extends survival benefit of radiation treatment in select glioblastoma patient-derived xenograft models

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6276-6276

2020

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Brain Distribution of a Panel of Epidermal Growth Factor Receptor Inhibitors Using Cassette Dosing in Wild-Type and Abcb1/Abcg2 -Deficient Mice

Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors

Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma

Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer

Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases

A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior

Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer

Molecular determinants of blood-brain barrier permeation

Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor

Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma

Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases

Central Nervous System Distribution of an Opioid Agonist Combination with Synergistic Activity

Lisdexamfetamine Pharmacokinetic Comparison Between Patients Who Underwent Roux-en-Y Gastric Bypass and Nonsurgical Controls

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

Semi-automated rapid quantification of brain vessel density utilizing fluorescent microscopy

High-dose MTX110 (soluble panobinostat) safely administered into the fourth ventricle in a nonhuman primate model

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier

Novel treatment strategies for brain tumors and metastases

Abstract 1832: Bioluminescent pharmacokinetics of luciferin in preclinical brain metastases of breast cancer models

Abstract 4172: Radiation-induced blood-tumor barrier permeability in a preclinical model of lung cancer brain metastasis

DDEL-09. HIGH DOSE MTX110 (SOLUBLE PANOBINOSTAT) SAFELY ADMINISTERED INTO THE FOURTH VENTRICLE IN A NON-HUMAN PRIMATE MODEL

Abstract 6276: Brain penetrant MDM2 inhibitor RG7388 extends survival benefit of radiation treatment in select glioblastoma patient-derived xenograft models

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