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Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review

RSC advances, 2020-08, Vol.1 (52), p.31139-31155

2020

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Novel quinoxaline derivatives as dual EGFR and COX-2 inhibitors: synthesis, molecular docking and biological evaluation as potential anticancer and anti-inflammatory agents

RSC advances, 2022-09, Vol.12 (39), p.2524-25216

2022

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Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4 H )-Oxazolone-Based Sulfonamides

Molecules (Basel, Switzerland), 2022-01, Vol.27 (3), p.671

2022

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Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

RSC advances, 2020-07, Vol.1 (45), p.26895-26916

2020

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Isolation and characterization of novel acetylcholinesterase inhibitors from Ficus benghalensis L. leaves

RSC advances, 2020-10, Vol.10 (60), p.36920-36929

2020

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Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1177

2021

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Targeting 3CLpro and SARS-CoV-2 RdRp by Amphimedon sp. Metabolites: A Computational Study

Molecules (Basel, Switzerland), 2021-06, Vol.26 (12), p.3775

2021

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Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1067-1078

2021

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Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Applied sciences, 2021-08, Vol.11 (15), p.6847

2021

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In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3125

2020

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Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors

European journal of medicinal chemistry, 2021-01, Vol.209, p.112904, Article 112904

2021

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EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules

Bioorganic chemistry, 2019-08, Vol.89, p.102997-102997, Article 102997

2019

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Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production

European journal of medicinal chemistry, 2018-02, Vol.146, p.260-273

2018

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Targeting endoplasmic reticulum stress, Nrf-2/HO-1, and NF-κB by myristicin and its role in attenuation of ulcerative colitis in rats

Life sciences (1973), 2022-12, Vol.311 (Pt B), p.121187, Article 121187

2022

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Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives

Synthetic communications, 2020-10, Vol.50 (19), p.2924-2940

2020

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Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV

Bioorganic chemistry, 2021-07, Vol.112, p.104920, Article 104920

2021

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Chemistry and Applications of Functionalized 2,4‐Thiazolidinediones

European journal of organic chemistry, 2023-05, Vol.26 (19), p.n/a

2023

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Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities

Bioorganic chemistry, 2022-12, Vol.129, p.106171-106171, Article 106171

2022

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Novel pyrrol-2(3H)-ones and pyridazin-3(2H)-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors

Bioorganic chemistry, 2018-10, Vol.80, p.151-163

2018

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Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors

Bioorganic chemistry, 2020-12, Vol.105, p.104439, Article 104439

2020

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Synthesis, antimicrobial studies, and molecular docking of some new dihydro-1,3,4-thiadiazole and pyrazole derivatives derived from dithiocarbazates

Synthetic communications, 2021-02, Vol.51 (4), p.570-584

2021

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Optimization of the synthesis of het/aryl-amidoximes using an efficient green chemistry

Synthetic communications, 2020-04, Vol.50 (8), p.1217-1231

2020

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Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors

Bioorganic chemistry, 2022-02, Vol.119, p.105564-105564, Article 105564

2022

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Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies

Bioorganic chemistry, 2019-04, Vol.85, p.577-584

2019

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Antiproliferative activity of new pentacyclic triterpene and a saponin from Gladiolus segetum Ker-Gawl corms supported by molecular docking study

RSC advances, 2020-06, Vol.10 (38), p.22730-22741

2020

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Molecular targets and anticancer activity of quinoline-chalcone hybrids: literature review

Novel quinoxaline derivatives as dual EGFR and COX-2 inhibitors: synthesis, molecular docking and biological evaluation as potential anticancer and anti-inflammatory agents

Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4 H )-Oxazolone-Based Sulfonamides

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Isolation and characterization of novel acetylcholinesterase inhibitors from Ficus benghalensis L. leaves

Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors

Targeting 3CLpro and SARS-CoV-2 RdRp by Amphimedon sp. Metabolites: A Computational Study

Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction

Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors

Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors

EGFR inhibitors and apoptotic inducers: Design, synthesis, anticancer activity and docking studies of novel xanthine derivatives carrying chalcone moiety as hybrid molecules

Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production

Targeting endoplasmic reticulum stress, Nrf-2/HO-1, and NF-κB by myristicin and its role in attenuation of ulcerative colitis in rats

Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives

Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV

Chemistry and Applications of Functionalized 2,4‐Thiazolidinediones

Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities

Novel pyrrol-2(3H)-ones and pyridazin-3(2H)-ones carrying quinoline scaffold as anti-proliferative tubulin polymerization inhibitors

Design, synthesis and molecular modeling of novel aryl carboximidamides and 3-aryl-1,2,4-oxadiazoles derived from indomethacin as potent anti-inflammatory iNOS/PGE2 inhibitors

Synthesis, antimicrobial studies, and molecular docking of some new dihydro-1,3,4-thiadiazole and pyrazole derivatives derived from dithiocarbazates

Optimization of the synthesis of het/aryl-amidoximes using an efficient green chemistry

Utilization of cyanopyridine in design and synthesis of first-in-class anticancer dual acting PIM-1 kinase/HDAC inhibitors

Novel aryl carboximidamide and 3-aryl-1,2,4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies

Antiproliferative activity of new pentacyclic triterpene and a saponin from Gladiolus segetum Ker-Gawl corms supported by molecular docking study

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