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Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

The Journal of clinical investigation, 2014-05, Vol.124 (5), p.2023-2036

2014

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Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Cerebral cortex (New York, N.Y. 1991), 2016-01, Vol.26 (1), p.414-426

2016

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Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases

Neuropharmacology, 2018-07, Vol.136 (Pt C), p.449-458

2018

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M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

The Journal of clinical investigation, 2017-02, Vol.127 (2), p.487-499

2017

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TRPV3 in Drug Development

Pharmaceuticals (Basel, Switzerland), 2016-09, Vol.9 (3), p.55

2016

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Discovery of α‑Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein

ACS medicinal chemistry letters, 2024-04, Vol.15 (4), p.501-509

2024

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Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

Nature chemical biology, 2020-03, Vol.16 (3), p.240

2020

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Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

Molecular pharmacology, 2018-06, Vol.93 (6), p.645-656

2018

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Bitopic Binding Mode of an M 1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

Molecular pharmacology, 2018-06, Vol.93 (6), p.645-656

2018

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Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors

British journal of pharmacology, 2019-01, Vol.176 (1), p.110-126

2019

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Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

Psychopharmacology, 2014-03, Vol.231 (6), p.1105-1124

2014

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Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M 1 receptors

British journal of pharmacology, 2019-01, Vol.176 (1), p.110-126

2019

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Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH‐SY5Y cells: contribution of voltage‐operated Ca2+ channels and Ca2+ stores

Journal of neurochemistry, 2002-05, Vol.81 (3), p.606-614

2002

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Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors

Molecular pharmacology, 2008-06, Vol.73 (6), p.1838-1843

2008

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Pharmacological profiling of the TRPV3 channel in recombinant and native assays

British journal of pharmacology, 2014-05, Vol.171 (10), p.2631-2644

2014

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Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum

The Journal of pharmacology and experimental therapeutics, 2002-07, Vol.302 (1), p.197

2002

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Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes

Pharmacology research & perspectives, 2015-12, Vol.3 (6), p.e00191-n/a

2015

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Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

European journal of pharmacology, 2000-03, Vol.393 (1), p.51-58

2000

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The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain

European journal of pharmacology, 2010-09, Vol.643 (2), p.218-224

2010

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TRP channels as emerging targets for pain therapeutics

Expert opinion on therapeutic targets, 2009-01, Vol.13 (1), p.69-81

2009

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Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380

Neuropharmacology, 2004-11, Vol.47 (6), p.848-859

2004

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Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

Neuropsychopharmacology (New York, N.Y.), 2010-03, Vol.35 (4), p.855-869

2010

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An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

The Journal of biological chemistry, 2016-04, Vol.291 (17), p.8862-8875

2016

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Gain and Loss of Function of P2X7 Receptors: Mechanisms, Pharmacology and Relevance to Diabetic Neuropathic Pain

Molecular pain, 2014-06, Vol.10 (1), p.37-37

2014

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Discovery of two novel, selective agonist radioligands as PET imaging agents for the M1 muscarinic acetylcholine receptor

The Journal of nuclear medicine (1978), 2017-05, Vol.58, p.546

2017

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Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss

TRPV3 in Drug Development

Discovery of α‑Amidobenzylboronates as Highly Potent Covalent Inhibitors of Plasma Kallikrein

Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs

Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

Bitopic Binding Mode of an M 1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M1 receptors

Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

Identification and pharmacological profile of SPP1, a potent, functionally selective and brain penetrant agonist at muscarinic M 1 receptors

Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH‐SY5Y cells: contribution of voltage‐operated Ca2+ channels and Ca2+ stores

Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors

Pharmacological profiling of the TRPV3 channel in recombinant and native assays

Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum

Activation of transient receptor potential ankyrin 1 induces CGRP release from spinal cord synaptosomes

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum

The subtype-selective nicotinic acetylcholine receptor positive allosteric potentiator 2087101 differentially facilitates neurotransmission in the brain

TRP channels as emerging targets for pain therapeutics

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380

Molecular Mechanisms of Action and In Vivo Validation of an M4 Muscarinic Acetylcholine Receptor Allosteric Modulator with Potential Antipsychotic Properties

An Antibody Biosensor Establishes the Activation of the M1 Muscarinic Acetylcholine Receptor during Learning and Memory

Gain and Loss of Function of P2X7 Receptors: Mechanisms, Pharmacology and Relevance to Diabetic Neuropathic Pain

Discovery of two novel, selective agonist radioligands as PET imaging agents for the M1 muscarinic acetylcholine receptor

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